Beneficial Effects of Ethyl Pyruvate through Inhibiting High-Mobility Group Box 1 Expression and TLR4/NF-κB Pathway after Traumatic Brain Injury in the Rat

The biochemical basis for the anti-inflammatory and cytoprotective actions of ethyl pyruvate and related compounds

(2010) Kenneth K. Kao et al.   BIOCHEMICAL PHARMACOLOGY

Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the rat

(2010) Nobuhiro Moro et al.   EXPERIMENTAL NEUROLOGY

Pioglitazone attenuates mitochondrial dysfunction, cognitive impairment, cortical tissue loss, and inflammation following traumatic brain injury

(2010) Andrew Sauerbeck et al.   EXPERIMENTAL NEUROLOGY

Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage

(2010) Yu Zhou et al.   MEDIATORS OF INFLAMMATION

Disruption of Nrf2 Enhances the Upregulation of Nuclear Factor-kappaB Activity, Tumor Necrosis Factor-α, and Matrix Metalloproteinase-9 after Spinal Cord Injury in Mice

(2010) Lei Mao et al.   MEDIATORS OF INFLAMMATION

Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage

(2010) Bolin Cai et al.   MEDIATORS OF INFLAMMATION

High Mobility Group Box 1 Is Upregulated After Spinal Cord Injury and Is Associated With Neuronal Cell Apoptosis

(2010) Hideyuki Kawabata et al.   SPINE

Ethyl Pyruvate Attenuates Spinal Cord Ischemic Injury with a Wide Therapeutic Window through Inhibiting High-mobility Group Box 1 Release in Rabbits

(2009) Qiang Wang et al.   ANESTHESIOLOGY

Targeting HMGB1 in inflammation

(2009) Huan Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

What has inflammation to do with traumatic brain injury?

(2009) David Cederberg et al.   CHILDS NERVOUS SYSTEM

Simvastatin reduces secondary brain injury caused by cortical contusion in rats: Possible involvement of TLR4/NF-κB pathway

(2009) Gang Chen et al.   EXPERIMENTAL NEUROLOGY

Pathophysiology of traumatic brain injury

(2009) Mark W. Greve et al.   MOUNT SINAI JOURNAL OF MEDICINE

BENEFICIAL EFFECTS OF ETHYL PYRUVATE IN A MOUSE MODEL OF SPINAL CORD INJURY

(2009) Tiziana Genovese et al.   SHOCK

Ethyl pyruvate reduces the development of zymosan-induced generalized inflammation in mice

(2008) Rosanna Di Paola et al.   CRITICAL CARE MEDICINE

Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury

(2008) Wei Jin et al.   CYTOKINE

Induction and subcellular localization of high-mobility group box–1 (HMGB1) in the postischemic rat brain

(2007) Jung-Bin Kim et al.   JOURNAL OF NEUROSCIENCE RESEARCH