Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients

Canadian Thoracic Society Asthma Management Continuum – 2010 Consensus Summary for Children Six Years of Age and Over, and Adults

(2016) M Diane Lougheed et al.   Canadian Respiratory Journal

In Vivo Characterization of GSK256066, a High-Affinity Inhaled Phosphodiesterase 4 Inhibitor

(2011) A. T. Nials et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Global Analysis of the Impact of Environmental Perturbation on cis-Regulation of Gene Expression

(2011) Elin Grundberg et al.   PLoS Genetics

Pharmacology of a potent and selective inhibitor of PDE4 for inhaled administration

(2010) Richard W. Chapman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The preclinical pharmacology of roflumilast – A selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease

(2010) Armin Hatzelmann et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene

(2009) Blanca E. Himes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Global patterns of cis variation in human cells revealed by high-density allelic expression analysis

(2009) Bing Ge et al.   NATURE GENETICS

Underpinning compartmentalised cAMP signalling through targeted cAMP breakdown

(2009) Miles D. Houslay   TRENDS IN BIOCHEMICAL SCIENCES

ARG1 Is a Novel Bronchodilator Response Gene: Screening and Replication in Four Asthma Cohorts

(2008) A. A. Litonjua et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

PDE4 inhibitors: current status

(2008) D Spina   BRITISH JOURNAL OF PHARMACOLOGY

Stroke Genetics – Focus on PDE4D Gene

(2008) Anjana Munshi et al.   International Journal of Stroke

A Major Functional Role for Phosphodiesterase 4D5 in Human Airway Smooth Muscle Cells

(2007) Charlotte K. Billington et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY