Toll-Like Receptor Signaling Pathways—Therapeutic Opportunities

Expression of toll-like receptor-9 is increased in poorly differentiated prostate tumors

(2010) Marja-Riitta Väisänen et al.   PROSTATE

Toll-like Receptors in Autoimmunity

(2009) Maria Fischer et al.   Annals of the New York Academy of Sciences

Regression of systemic lupus erythematosus after development of an acquired Toll-like receptor signaling defect and antibody deficiency

(2009) Marcella Visentini et al.   ARTHRITIS AND RHEUMATISM

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress

(2009) Luke A. J. O'Neill   IMMUNOLOGICAL REVIEWS

Selective up-regulation of CDK2 is critical for TLR9 signaling stimulated proliferation of human lung cancer cell

(2009) Lin Xu et al.   IMMUNOLOGY LETTERS

Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

(2009) Sotiria Tzima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased Inflammation, Impaired Bacterial Clearance, and Metabolic Disruption after Gram-Negative Sepsis in Mkp-1-Deficient Mice

(2009) W. J. Frazier et al.   JOURNAL OF IMMUNOLOGY

Critical Role of TLR2 and TLR4 in Autoantibody Production and Glomerulonephritis in lpr Mutation-Induced Mouse Lupus

(2009) A. Lartigue et al.   JOURNAL OF IMMUNOLOGY

The kinase activities of interleukin-1 receptor associated kinase (IRAK)-1 and 4 are redundant in the control of inflammatory cytokine expression in human cells

(2009) Kyung W. Song et al.   MOLECULAR IMMUNOLOGY

TLR9 Signaling Promotes Tumor Progression of Human Lung Cancer Cell In Vivo

(2009) Tao Ren et al.   PATHOLOGY & ONCOLOGY RESEARCH

Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus

(2009) C. O. Jacob et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and genetic evidence that the Mal/TIRAP allele variant 180L has been selected by providing protection against septic shock

(2009) B. Ferwerda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor 2 variants are associated with acute reactive arthritis

(2008) Florence W. L. Tsui et al.   ARTHRITIS AND RHEUMATISM

Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology

(2008) S. Baenziger et al.   BLOOD

Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk

(2008) Victoria L. Stevens et al.   INTERNATIONAL JOURNAL OF CANCER

Toll-Like Receptor-9 Expression Is Inversely Correlated with Estrogen Receptor Status in Breast Cancer

(2008) Arja Jukkola-Vuorinen et al.   Journal of Innate Immunity

Toll-like receptor 9 (TLR9) agonists in the treatment of cancer

(2008) A M Krieg   ONCOGENE

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Acetylation of MKP-1 and the Control of Inflammation

(2008) H. Chi et al.   Science Signaling