Article
Instruments & Instrumentation
Thomas Tice
Summary: Long-acting injectables have had a significant impact on clinical medicine, with contributions from various fields and pioneers who envisioned and implemented new drug delivery concepts over 50 years ago.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Nanoscience & Nanotechnology
Hong-Jyuan Jian, Anisha Anand, Jui-Yang Lai, Binesh Unnikrishnan, Huan-Tsung Chang, Scott G. Harroun, Chih-Ching Huang
Summary: Effective treatment of infectious keratitis requires the elimination of pathogens, reduction of inflammation, and prevention of corneal damage. A nanocomposite (Arg-CQDs/pCur) consisting of arginine-derived carbon quantum dots (Arg-CQDs) and polymeric curcumin (pCur) was prepared. The Arg-CQDs/pCur nanocomposite showed combined antibacterial, antioxidative, anti-inflammatory, and pro-proliferative properties, making it an effective treatment for bacterial keratitis.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Materials Science, Biomaterials
V Deineka, O. Sulaieva, N. Pernakov, J. Radwan-Praglowska, L. Janus, V Korniienko, Ye Husak, A. Yanovska, I Liubchak, A. Yusupova, M. Piatkowski, A. Zlatska, M. Pogorielov
Summary: Research has shown that new hemostatic materials based on chitosan have high hemostatic performance and biocompatibility, with electrospinning-made chitosan copolymers significantly improving in vivo biocompatibility and degradation. Chitosan aerogel has high antibacterial activity and is suitable for hemostatic patch development, but is not recommended for visceral application.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Materials Science, Biomaterials
Debasrita Bharatiya, Swapnita Patra, Biswajit Parhi, Sarat K. Swain
Summary: This review paper discusses the parameters influencing the biological activities of PNCs and explores the potential of PNCs in biomedical applications.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Adwaita S. R. Nair, Sudeepa Devi, Subhash Mandal, Upendra K. Tripathi, Debmalya Roy, N. Eswara Prasad
Summary: This study focused on the effect of different geometries of functional carbon nanofillers on the enzymatic degradation of hydrogels, as well as the noncovalent interactions between polymer and filler phases. The exposed surface of embedded nanomaterials in a polymeric matrix was critical for interactions with enzymes, leading to increased enzymatic degradation of nanocomposites. The research found that the structure-property studies of nanocomposite hydrogels for biodegradability could potentially guide the design of high-performance biomedical devices.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Engineering, Chemical
Samyar Zabihi, Sahar Jamshidian, Roozbeh Soltani, Rasool Pelalak, Zahra Heidari, Azam Marjani, Mahdi Ghadiri
Summary: Large-pore mesoporous silica FDU-12 was synthesized and functionalized with silane coupling agents bearing methacrylate and diamino groups. Diamino-functionalized FDU-12/polyamide 6 and methacrylate-functionalized FDU-12/poly(methyl methacrylate) nanocomposites were prepared via in situ polymerization approach. The synthesized nanocomposites showed acceptable performance for Cd2+ uptake, as demonstrated by experimental and computational results.
CHEMICAL ENGINEERING & TECHNOLOGY
(2021)
Article
Nanoscience & Nanotechnology
Minho Lee, Song- Han, Changkyu Kim, Subramaniam Velumani, Arum Han, Abdel Hadi Kassiba, Homero Castaneda
Summary: The ultrathin nanocomposite coatings of ZrO2/ZnO/TiO2 on stainless steel were found to provide excellent corrosion protection and antimicrobial activity. The coating exhibited significantly higher impedance values compared to uncoated steel, and promoted cell proliferation and effective bacterial killing efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Chemistry, Applied
Kara M. de la Harpe, Pierre P. D. Kondiah, Thashree Marimuthu, Yahya E. Choonara
Summary: Suture materials are a significant biomedical material group, with an annual global market of $1.3 billion and over 12 million procedures using them. While suture materials have evolved from basic strips of linen to advanced synthetic polymer sutures, the journey towards the ideal suture material is still ongoing. The use of natural, carbohydrate polymers in suture material applications represents a new era of improved safety and efficacy in this field.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Praveesuda L. Michael, Yuen Ting Lam, Juichien Hung, Richard P. Tan, Miguel Santos, Steven G. Wise
Summary: The study demonstrates the excellent tolerability and biosafety of plasma-polymerized nanoparticles (PPNs) in vivo and in vitro, showing superior performance compared to commercially available nanoparticles.
Article
Materials Science, Multidisciplinary
Yixuan Shi, Zhe Xue, Ping Li, Shuo Yang, Dawei Zhang, Shaoxiong Zhou, Zhenpeng Guan, Yageng Li, Lu-Ning Wang
Summary: Zinc, as a biodegradable metal, has shown promise in biomedical applications due to its moderate degradation profile and good biocompatibility. Surface modification techniques have been used to optimize the degradation behavior and biological activity of biodegradable zinc, with significant progress made in cytocompatibility, osteogenesis, antibacterial performance, and degradation control. Proper surface design of biodegradable zinc alloys holds great potential for various biomedical applications.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Polymer Science
Vasant Kumar, Rutika Sehgal, Reena Gupta
Summary: PHAs, as environmentally friendly biopolymers, have potential in improving production and quality, but face challenges in production and quality control. Further exploration of their chemical makeup in blending can enhance their characteristics and applications.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Environmental
Xinling Wang, Chunhui Zhang, Zong Liu, Bingxu Quan, Wenjing Lu, Xuezhi Li, Peidong Su, Yuanhui Tang, Yuanqing Bu, Rong Zhou
Summary: This study developed a modified conductive ceramic composite membrane by incorporating reduced graphene oxide (rGO) and carbon nanotubes (CNTs) into polypyrrole (PPy) through an oxidative polymerization-self-assembly method. The modified membrane exhibited excellent electrical conductivity and stability, effectively removing pollutants in wastewater and improving the pH of pickling wastewater. Furthermore, the membrane showed minimal flux decay after multiple runs and the electric field treatment effectively slowed membrane fouling. This approach provides a clean and effective technique for membrane contamination control.
ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY
(2023)
Article
Materials Science, Multidisciplinary
Pei Feng, Kai Wang, Yang Shuai, Shuping Peng, Yongbin Hu, Cijun Shuai
Summary: This paper presents a method to prevent the aggregation of carbon nanotubes (CNT) and hydroxyapatite (HA) in a biopolymer scaffold by in situ synthesizing HA nanoparticles on the surface of carboxyl multi-walled CNT. The results showed that the scaffold with 12% cCNT-HA content exhibited significantly improved tensile and compressive strength compared to the pure PCL scaffold. Additionally, the scaffold displayed good bioactivity for inducing the formation of apatite mineralization and demonstrated good cytocompatibility for cell attachment, growth, and proliferation.
MATERIALS TODAY ADVANCES
(2022)
Article
Chemistry, Physical
G. Gonzalez-Ulloa, M. Jimenez-Rosado, M. Rafii-El-Idrissi Benhnia, A. Romero, E. Ruiz-Mateos, F. J. Ostos, V. Perez-Puyana
Summary: In the field of regenerative medicine, hydrogels are widely recognized as a suitable option for tissue regeneration due to their elastic properties and high water absorption capacity. This study aimed to develop and characterize polymeric hydrogels based on collagen and gelatin, both of which are considered good candidates due to their biocompatibility. The results showed that hydrogels formed from the mixture of collagen and gelatin retained the viscoelastic properties of collagen while demonstrating low cytotoxicity and hemocompatibility similar to gelatin. However, further research is needed to address the suboptimal thermal characteristics for biomedical applications.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Energy & Fuels
Pengxiang Jiao, Cuiqin Fang, Dong Zhang
Summary: Organic/inorganic composite electrolytes are prepared via in-situ polymerization during cement hydration, effectively addressing the issues of low dosage and poor dispersion of polymers. The resulting composite electrolyte exhibits excellent ionic conductivity and mechanical properties, and can achieve high specific capacitance and energy density when combined with structural supercapacitors.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Biophysics
Vineeth M. Vijayan, Remya Komeri, Sunita P. Victor, Jayabalan Muthu
COLLOIDS AND SURFACES B-BIOINTERFACES
(2015)
Article
Biophysics
Shivaram Selvam, Madhav V. Pithapuram, Sunita P. Victor, Jayabalan Muthu
COLLOIDS AND SURFACES B-BIOINTERFACES
(2015)
Article
Biotechnology & Applied Microbiology
Sunita P. Victor, V. M. Vineeth, Remya Komeri, Shivaram Selvam, Jayabalan Muthu
JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS
(2015)
Article
Biophysics
Vineeth M. Vijayan, Sachin J. Shenoy, Sunita P. Victor, Jayabalan Muthu
COLLOIDS AND SURFACES B-BIOINTERFACES
(2016)
Article
Biophysics
Sunita Prem Victor, Willi Paul, V. M. Vineeth, Remya Komeri, Muthu Jayabalan, Chandra P. Sharma
COLLOIDS AND SURFACES B-BIOINTERFACES
(2016)
Article
Chemistry, Physical
Sunita Prem Victor, Chandra P. Sharma, K. Sreenivasan
APPLIED SURFACE SCIENCE
(2011)
Article
Biophysics
Sunita Prem Victor, Chandra P. Sharma
COLLOIDS AND SURFACES B-BIOINTERFACES
(2011)
Article
Biophysics
Sunita Prem Victor, Chandra P. Sharma
COLLOIDS AND SURFACES B-BIOINTERFACES
(2013)
Article
Biophysics
A. C. Jayalekshmi, Sunita Prem Victor, Chandra P. Sharma
COLLOIDS AND SURFACES B-BIOINTERFACES
(2013)
Article
Chemistry, Multidisciplinary
Sunita Prem Victor, Willi Paul, Muthu Jayabalan, Chandra P. Sharma
Article
Chemistry, Multidisciplinary
Sunita Prem Victor, Willi Paul, Muthu Jayabalan, Chandra P. Sharma
Article
Engineering, Biomedical
Sunita Prem Victor, Chandra P. Sharma
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2011)
Review
Cell & Tissue Engineering
Sunita Prem Victor, Chandra P. Sharma
JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING
(2012)
Proceedings Paper
Biochemical Research Methods
Sunita Prem Victor, Chandra P. Sharma
PROTEINS AT INTERFACES III: STATE OF THE ART
(2012)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
