Article
Polymer Science
Hongyi Gan, Takumi Okada, Satoshi Kimura, Ken-ichi Kasuya, Tadahisa Iwata
Summary: This study utilized a simple melt-homogenizing method to produce microbeads from four biodegradable polyesters, which are commonly found in cosmetics and personal care products. The microbeads ranged in size from 25 to 200 μm, had smooth surfaces, and exhibited comparable compression strengths to conventional microbeads like polyethylene and polypropylene. Particularly, poly(butylene succinate adipate) and poly[(R)-3-hydroxybutyrate] microbeads showed high biodegradability and have the potential to replace conventional microbeads.
POLYMER DEGRADATION AND STABILITY
(2023)
Article
Engineering, Biomedical
Xian Tong, Li Zhu, Yihao Wu, Yiting Song, Kun Wang, Shengbin Huang, Yuncang Li, Jianfeng Ma, Cuie Wen, Jixing Lin
Summary: This study reports the development of a new biodegradable Fe/Zn-3Cu composite fabricated by infiltration casting and hot-rolling, which shows high mechanical strength, fast degradation rate, good biocompatibility, higher cell viability, and efficient antibacterial ability. The HR Fe/Zn-3Cu composite has great potential as a biodegradable implant material for bone-fixation applications.
ACTA BIOMATERIALIA
(2022)
Article
Engineering, Chemical
Soilikki Kotanen, Minna Poikelispaa, Alexander Efimov, Tapani Harjunalanen, Christopher Mills, Timo Laaksonen, Essi Sarlin
Summary: Polyurethane/polyhydroxyurethane (PU/PHU) hybrid materials show potential as alternatives to PU adhesives with good mechanical and adhesive properties, but are susceptible to water uptake leading to potential bond failure. After water immersion, cohesive strength of PU/PHU increases while adhesive strength decreases, requiring careful application design for optimal usage.
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
(2021)
Article
Crystallography
Weiyan Jiang, Wenzhou Yu
Summary: The application of biodegradable alloys in orthopedic implants has gained significant attention. The research investigated the performance of a Mg-1Zn-xSn alloy and found that it exhibited enhanced mechanical properties and in vitro degradation performance compared to the Mg-1Zn alloy. The Mg-1Zn-1.0Sn alloy showed particularly promising results, with extremely low corrosion rate and hydrogen release, as well as zero cytotoxicity grade.
Article
Polymer Science
Diana Favero, Victoria Marcon, Lucas Dall Agnol, Clara M. Gomez, Ana Cros, Nuria Garro, Maria J. Sanchis, Marta Carsi, Carlos A. Figueroa, Otavio Bianchi
Summary: This study investigates the effect of different chain extenders on the structure-property relationships of soy-based polyurethanes during hydrolytic degradation. It is found that the addition of chain extenders accelerates the degradation of flexible domains, resulting in a stiffer and more brittle polymer. Hydrolytic degradation also leads to the formation of new infrared absorption peaks and increased phase separation.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Chemical
Maja D. Valcic, Suzana M. Cakic, Ivan S. Ristic, Jelena D. Cakic, Miroslav J. Cvetinov, Csanadi J. Janos
Summary: A series of nontoxic acrylated waterborne polyurethane/silica hybrid composites were synthesized with controlled crosslink density and different amounts of nanosilica, resulting in improved thermal stability and mechanical properties of the hybrid composite materials.
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
(2021)
Article
Materials Science, Multidisciplinary
Huai Yao, Boyang Fang, Huina Shi, Harishchandra Singh, Marko Huttula, Wei Cao
Summary: The study investigated the microstructure, mechanical properties, and degradation behavior of as-extruded Mg-1.8Zn-0.5Zr-xGd alloys. It was found that the alloys exhibited optimal performance under certain extrusion conditions. The presence of various second phases in the alloys showed different behaviors with increasing Gd content, leading to variations in mechanical properties and corrosion resistance.
JOURNAL OF MATERIALS SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Dinesh Kumar Chelike, Senthil A. Gurusamy A. Thangavelu
Summary: A facile synthesis of isocyanate free polyurethanes (PU) was achieved by reacting biodegradable cyclic carbonate with sustainable diamines via chemical modification. The resulting PU films showed high onset degradation temperature and were further characterized and studied for various properties and behaviors.
Article
Materials Science, Multidisciplinary
Soo Kyung Han, Minju Song, Kangho Choi, Sung-Wook Choi
Summary: This study fabricated PCL-based PU foam scaffolds with highly porous inner and outer structures using a gas foaming technique, achieving ductile properties with high compression strength. In vitro tests showed low toxicity and high ALP activity in MC3T3-E1 cells, and customized PU scaffolds with specific features were prepared through a tailored fabrication method. The PU scaffolds demonstrated wide potential applications for tissue engineering due to their controlled mechanical properties and highly porous structure.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2021)
Article
Chemistry, Physical
Chengwei Ji, Aibin Ma, Jinghua Jiang, Haoran Wu, Huan Liu, Sensen Guo, Yuxuan Yuan
Summary: A combined process of cold rolling and equal channel angular pressing (ECAP) was developed to improve the mechanical properties and localized corrosion of Zn-0.6Mg alloy for biodegradable implants. After cold rolling and ECAP processing, the alloy exhibited significantly improved strength and ductility compared to the as-cast alloy, with the alloy processed by 8-pass ECAP+CR75% (ER) showing the best mechanical properties. The eutectic phase fragmentation and grain refinement caused by cold rolling and ECAP process reduced the galvanic corrosion tendency of the alloy, resulting in improved corrosion resistance.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Materials Science, Multidisciplinary
Ju Hui Kang, Joon Hyuk Lee, Sangkug Lee, Dong Hack Suh, Bongjun Yeom
Summary: Bioderivatives of diester monomers are used to synthesize phthalate-based copolyesters, which enhance degradability without significant loss of thermal stability.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Polymer Science
Kai Weng, Fang Li, Yumiko Takayama, Motomu Nishijo, Toshihisa Tanaka
Summary: This study investigated the effects of different soaking solvents on the crystallization and stretching properties of polymer films. Different results were observed in terms of microcrystal nucleation and stretching structure, depending on the soaking conditions. Soaking in ice-water or hexane promoted the formation of microcrystal nucleation and increased the tensile strength, while soaking in methanol inhibited the mobility and stretchability. Soaking in air maintained the amorphous state of the molecular chains.
Article
Engineering, Biomedical
Alper Ekinci, Andy Gleadall, Andrew A. Johnson, Ling Li, Xiaoxiao Han
Summary: The study examines the mechanical and hydrolytic properties of FFF monolayered PLA thin films at 37 degrees C in vitro degradation. It found that the mechanical properties such as Young's modulus and ultimate tensile strength decreased, while the crystallinity increased, with the early stage more sensitive to crystallinity and the late stage dominated by molecular weight.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Chenkai Zhu, Wuxiang Zhang, Zhenzong Shao, Zixun Wang, Baoning Chang, Xilun Ding, Yang Yang
Summary: This article introduces a novel phosphate glass fiber-poly(vinyl alcohol) (PVA) composite hydrogel, where the presence of stiff glass fiber not only improves the mechanical properties of the hydrogel but also enhances the molecular structure and metabolic environment, making it a promising material for cartilage repair.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Materials Science, Multidisciplinary
Ximei Xiao, Bing Wang, Enyang Liu, Hongrui Liu, Lin Liu, Wenke Xu, Shaohua Ge, Jinlong Shao
Summary: This study investigates the properties of Zn-Ag alloys and finds that adding Ag to Zn not only improves its mechanical and antibacterial properties but also promotes cell proliferation and bone repair, suggesting the potential of Zn-Ag alloys as implant materials in orthopedics.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Polymer Science
Hossein Molavi, Akbar Shojaei, Seyyed Abbas Mousavi, Seyyed Ahmad Ahmadi
JOURNAL OF APPLIED POLYMER SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Pooria Rahmani, Akbar Shojaei, Nahid Pirhady Tavandashti
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2020)
Article
Engineering, Biomedical
Hoshyar Gholami, Hamid Yeganeh
BIOMEDICAL MATERIALS
(2020)
Article
Engineering, Mechanical
Farhad Ahmadijokani, Akbar Shojaei, Sara Dordanihaghighi, Erfan Jafarpour, Sahar Mohammadi, Mohammad Arjmand
Article
Materials Science, Biomaterials
Samaneh Salkhi Khasraghi, Akbar Shojaei, Uttandaraman Sundararaj
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2020)
Article
Polymer Science
Hoshyar Gholami, Hamid Yeganeh
Summary: In this study, biobased non-isocyanate polyurethane (NIPU) membranes with suitable physicomechanical and biological properties for wound dressings are introduced. These dressings can protect damaged skin tissue from external forces, maintain a moist environment, and promote wound healing.
EUROPEAN POLYMER JOURNAL
(2021)
Review
Chemistry, Physical
Pooria Rahmani, Akbar Shojaei
Summary: Hydrogels have shown great potential in wearable devices by overcoming the drawbacks of other materials, offering intrinsic electrical conductivity, suitable mechanical properties, and biocompatibility. Researchers are focusing on developing methods, design strategies, sensing performance, and applications of hydrogel-based strain sensors.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Rahman Mohammadkhani, Akbar Shojaei, Pooria Rahmani, Nahid Pirhady Tavandashti, Mahsa Amouzegar
Summary: In this study, nano-sized diamond particles were functionalized through dry thermal oxidation and wet chemistry, leading to the synthesis of PANI/ND hybrid nanostructures which were incorporated into epoxy coatings to enhance corrosion protection. Experimental results indicated that PANI/ND5%-epoxy nanocomposite exhibited improved corrosion resistance compared to other formulations.
DIAMOND AND RELATED MATERIALS
(2021)
Article
Polymer Science
Samaneh Salkhi Khasraghi, Akbar Shojaei, Mohsen Janmaleki, Uttandaraman Sundararaj
Summary: In this study, multifunctional magnetic shape memory polymer nanocomposites were successfully synthesized, showing excellent shape fixity and recovery properties, as well as biocompatibility.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Biomedical
Masoud Babaahmadi, Hamid Yeganeh
Summary: The study aimed to develop high-efficiency wound dressings with noncytotoxicity, proper mechanical strength, and the ability to maintain a hygienic environment over wounded skin tissue. This was achieved through the synthesis of a novel silane crosslinking agent with antibacterial guanidinium chloride functional group. The resulting dressings showed good tensile strength, dimensional stability, and fluid handling capacity, while also demonstrating excellent biocompatibility and antibacterial properties.
BIOMEDICAL MATERIALS
(2023)
Article
Pharmacology & Pharmacy
Athar Mahdieh, Hamid Yeganeh, Sverre Arne Sande, Bo Nystrom
Summary: This study developed a novel cationic soybean oil-based polyurethane ionene nanocarrier for targeted drug delivery, which showed high efficacy in inhibiting tumor growth. The carrier could efficiently load the anticancer drug 5-fluorouracil and its inhibitory effect on tumor growth was enhanced when folic acid was added as a targeting moiety.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Polymer Science
Hamidreza Moeini, Saeed Pourmahdian, Hamid Yeganeh
Summary: This work describes the preparation of thermally curable benzoxazine-modified polyurethanes with pendant carboxylic acid moieties, which have potential as organic coatings with enhanced thermal stability and electrical insulation properties. Spectroscopic methods were utilized to characterize the proposed structures of the starting materials and final polymeric coatings and confirmation of co-presence of urethane bonds and benzoxazine rings. The XPUBs displayed high dielectric strength of up to 38 kV/mm, low dielectric constant of less than 3, and a dissipation factor of approximately 6.
Article
Polymer Science
Masoud Babaahmadi, Hamid Yeganeh
Summary: The objective of this study is to fabricate wound dressing membranes with effective antibacterial activity, good biocompatibility with fibroblast cells, appropriate mechanical properties, and the ability to maintain a moist environment. A new silane functional polyhexamethylene guanidine hydrochloride was synthesized and used as a crosslinker for a polymeric matrix. The resulting dressing membranes showed good tensile strength, suitable fluid handling capacity, excellent biocompatibility, and potent antibacterial activity.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Engineering, Biomedical
Alireza Rezapour-Lactoee, Hamid Yeganeh, Reza Gharibi, Peiman Brouki Milan
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2020)
Article
Engineering, Biomedical
Shiva Asadpour, Hamid Yeganeh, Farzaneh Khademi, Hossein Ghanbari, Jafar Ai
BIOMEDICAL MATERIALS
(2020)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)