Article
Chemistry, Multidisciplinary
Mengyuan Wang, Shizhuo Su, Xin Zhong, Derui Kong, Bo Li, Yujie Song, Chunman Jia, Yifan Chen
Summary: A novel redox-active organic-inorganic hybrid material based on tetrathiafulvalene derivatives and titanium dioxide has been synthesized, demonstrating remarkably enhanced photocatalytic performance. Characterizations of the hybrid reveal advantages such as stability and separation of photogenerated charges.
Article
Chemistry, Physical
Xueting Lian, Jin Gao, Feifei Guo, Ang Qian, Xiaogang Li
Summary: The Sol-gel method was used to prepare a Si-Ti-epoxy organic-inorganic hybrid composite sol, which was cured on the carbon steel surface to form a transparent film with excellent electrochemical protection performance and hydrophobicity. The Si-Ti-epoxy hybrid film has a denser structure, higher impedance modulus, and lower corrosion current density compared to a double-thick epoxy film.
SURFACES AND INTERFACES
(2021)
Article
Construction & Building Technology
Barbara Ferreira, Sara Sousa, Rui P. C. L. Sousa, Susana P. G. Costa, M. Manuela M. Raposo, Pier Parpot, Artur J. M. Valente, Rui F. P. Pereira, Rita B. Figueira
Summary: This work reports the synthesis of organic-inorganic hybrid membranes for potential optical fibre sensors for pH monitoring of concrete and reinforced concrete structures. The membranes were successfully obtained and showed promising results in simulated concrete pore solutions.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Rui P. C. L. Sousa, Rita B. Figueira, Emanuela Callone, Sandra Dire, Susana P. G. Costa, Maria Manuela M. Raposo
Summary: In this study, four novel organic-inorganic hybrid materials were synthesized using the sol-gel method. The materials were based on different molecular weights of Jeffamines and ECHETMS, and characterized using various techniques. The influence of Jeffamine molecular weight on the suitability of these materials as a supporting matrix for heteroaromatic probes was assessed and discussed, and the materials were found to exhibit interesting properties for a wide range of sensing applications.
Article
Materials Science, Multidisciplinary
Galtiere Correa Rego, Rafael Marinho Bandeira, Julia van Drunen, Germano Tremiliosi-Filho, Luiz Carlos Casteletti
Summary: Sol-gel technology was employed in this study to produce organic-inorganic hybrid coatings on AISI 1045 carbon steel for corrosion protection. The coatings were prepared using tetraethylorthosilicate (TEOS) and 3-(trimethoxysilyl)propyl methacrylate precursors. Thermal treatment of the coatings resulted in decreased thickness and improved scratch resistance. Electrochemical measurements showed that the coatings treated at 100 degrees C exhibited higher polarization resistance and less aggressive corrosion compared to higher temperature treatments.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Fang Jing, Yanmeng Guo, Bo Li, Yi-Fan Chen, Chunman Jia, Jianwei Li
Summary: This study reports benzo[1,2-b:4,5-b']dithiophene polymer as an ideal organic material for preparing hybrid materials with titanium dioxide (TiO2) that exhibit enhanced photocatalytic hydrogen production under visible light. The resulting hybrid material has a reduced energy band gap of 2.9 eV and achieves a stable photocatalytic hydrogen production performance after 40 hours of cycling. The improved water splitting is attributed to faster separation of electron-hole pairs and lower recombination of photocarrier ions.
CHINESE CHEMICAL LETTERS
(2022)
Article
Nanoscience & Nanotechnology
Yoshiki Shirai, Ayano Sasaki, Sayako Sato, Daisuke Aoki, Koji Arimitsu
Summary: Organic-inorganic materials have advantages of both organic and inorganic resins, yet hard coating films made of organic-inorganic mixtures of resins suffer from opacity and interface peeling problems. In this study, we successfully fabricated an organic-inorganic gradient film by impeding the movement of organic and inorganic resins and enhanced the gouge hardness by sol-gel reactions of inorganic resins. The resulting organic-inorganic gradient coating exhibited excellent gouge hardness, adhesion to organic substrates, and transparency.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Applied
Alvaro G. Braz, Sandra H. Pulcinelli, Celso Santilli
Summary: This study investigates the use of glycerol as a crosslinker for polyurethane, which is hybridized with a silica network. The results show that this organic-inorganic hybrid coating can effectively enhance the corrosion resistance of metal alloys.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Chemistry, Applied
Alvaro G. Braz, Sandra H. Pulcinelli, Celso V. Santilli
Summary: This study investigates glycerol as a crosslinker for polyurethane segments hybridized with a silica network for protective coatings. Evaluations were made on the structure, thermal stability, and corrosion protection of the coatings at different APTES/4,4'-MDI molar ratios, confirming the suitability of the PU-silica hybrid for anticorrosive thin coatings to protect metal alloys against corrosion.
PROGRESS IN ORGANIC COATINGS
(2022)
Review
Chemistry, Physical
Andrea Erigoni, Urbano Diaz
Summary: Organic-inorganic hybrid catalysts, especially those based on silica, have been extensively researched due to their combination of structural stability and versatility. This review focuses on the synthetic tools and chemistry behind the sol-gel syntheses of hybrid catalysts, as well as exemplificative studies on mono- and multi-functional silica-based catalysts with different active sites. Materials obtained through various approaches are compared in terms of properties and catalytic performances, aiming to provide useful information for researchers in the field.
Article
Chemistry, Multidisciplinary
Sacha Legrand, Rakib Kabir, Ari Karkkainen
Summary: A series of novel polysiloxanes derived from phenanthrenyl-containing monomers were prepared using sol-gel technology and free-radical polymerization. These polysiloxanes exhibit high refractive index, thermal stability, and resistance against aging, making them suitable for optoelectronic applications. The effects of crosslinking agent and chain packing density on the chemical, optical, and mechanical properties of the polysiloxanes and corresponding films were studied.
Article
Materials Science, Ceramics
Hiroyuki Hayashi, Keita Kouzai, Yuta Morimitsu, Isao Tanaka
Summary: Despite extensive research, accurately predicting successful synthesis conditions for new pseudo-binary oxides remains a challenge. This study introduces a synthesis-condition recommender system to efficiently explore a wide chemistry space and successfully discovered two yet-to-be-found pseudo-binary oxides through systematic synthesis experiments.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2022)
Article
Materials Science, Ceramics
E. Zanchetta, G. Della Giustina, A. Gandin, V Auzelyte, G. Brusatin
Summary: Direct printing of spin-on functional films is an efficient method to develop low-cost photonic nanodevices. In this study, high refractive index TiO2 micro- and nano-structures were obtained by combining thermal nanoimprint lithography with UV curing. The patterns were achieved by depositing a hybrid organic-inorganic spin-on film using sol-gel processing. The further UV irradiation converted the imprinted films to totally inorganic patterns, allowing high refractive indexes to be achieved. This novel strategy allows inorganic deep patterns to be fabricated without a calcination step.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Valentina Petrelli, Maria Michela Dell'Anna, Piero Mastrorilli, Veronica Viola, Michelina Catauro, Antonio D'Angelo
Summary: Hybrid materials composed of organic and inorganic components at the nanometer or molecular level have been studied for their potential applications in the biological and medical fields. This study focuses on the synthesis and characterization of a sol-gel-derived hybrid material consisting of silica, polyethylene glycol, and the antioxidant flavonoid quercetin. The structural and biological properties of the hybrid systems were investigated by varying the concentrations of quercetin and polyethylene glycol, and results showed a controlled release of quercetin over time, indicating its potential use in drug delivery.
APPLIED SCIENCES-BASEL
(2023)
Article
Materials Science, Ceramics
Matthias Klein, Soenke Steenhusen, Peer Loebmann
Summary: Solvent-free inorganic-organic hybrid polymers were prepared for digital light processing (DLP) and ink-jet printing. The resins were characterized in terms of viscosity, surface tension, and refractive index. Optical bulk components were prepared with both printing techniques and compared regarding their surface roughness and optical scattering. Inkjet 3D printing can avoid the haze of DLP samples. In addition, different quantum dots (QD) could be incorporated into the resins, resulting in complex 3D assemblies with DLP.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2022)
Article
Neurosciences
Alice Del Giovane, Mariagiovanna Russo, Linda Tirou, Helene Faure, Martial Ruat, Sonia Balestri, Carola Sposato, Francesco Basoli, Alberto Rainer, Abdelmoumen Kassoussi, Elisabeth Traiffort, Antonella Ragnini-Wilson
Summary: This study shows that non-canonical signaling pathways can promote the maturation and regeneration of myelin cells, suggesting a potential role in the treatment of demyelinating diseases.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Andrea Zancla, Pamela Mozetic, Monica Orsini, Giancarlo Forte, Alberto Rainer
Summary: TFM is a versatile technique used for measuring single-cell-generated forces, but issues with data analysis may limit its wider adoption. This review summarizes the latest advances in TFM research, emphasizing the importance of data analysis and providing a list of free data analytics tools.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Manuele Gori, Sara Maria Giannitelli, Gianluca Vadala, Rocco Papalia, Loredana Zollo, Massimo Sanchez, Marcella Trombetta, Alberto Rainer, Giovanni Di Pino, Vincenzo Denaro
Summary: The organic zwitterionic-poly(sulfobetaine methacrylate) [poly(SBMA)]-hydrogel has been demonstrated as an effective coating to reduce foreign-body reaction caused by intraneural electrodes. This hydrogel exhibits low fouling characteristics and can be successfully coated on Polyimide surfaces through covalent bonds, showing potential for long-term release of anti-fibrotic drugs. Its properties make it a promising diffusion-based delivery system for slow and controlled anti-inflammatory and anti-fibrotic drug release in vivo.
Article
Chemistry, Analytical
Joshua Di Tocco, Daniela Lo Presti, Alberto Rainer, Emiliano Schena, Carlo Massaroni
Summary: In recent years, soft and flexible strain sensors have been widely used in wearable devices for monitoring human motion and physiological parameters. This paper reports the manufacturing process of a silicone-textile composite resistive strain sensor and evaluates its performance.
Article
Materials Science, Multidisciplinary
Ersilia Fornetti, Stefano Testa, Francesca De Paolis, Claudia Fuoco, Sergio Bernardini, Victorio Pozo Devoto, Gorazd Bernard Stokin, Sara Maria Giannitelli, Alberto Rainer, Anne Bigot, Carmine Zoccali, Jacopo Baldi, Doriana Sandona, Roberto Rizzi, Claudia Bearzi, Giancarlo Forte, Stefano Cannata, Cesare Gargioli
Summary: This article introduces an approach to construct an in vitro neuromuscular junction (NMJ) using a microfluidic chip, aiming to establish a reliable and predictive human model to investigate synapse detriment in α-sarcoglycanopathy.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Engineering, Biomedical
E. Fornetti, F. De Paolis, C. Fuoco, S. Bernardini, S. M. Giannitelli, A. Rainer, D. Seliktar, F. Magdinier, J. Baldi, R. Biagini, S. Cannata, S. Testa, C. Gargioli
Summary: Three-dimensional (3D) bioprinting has emerged as an optimal tool for tissue engineering. The extrusion-based approach is the most suitable for skeletal muscle tissue engineering due to its ability to produce parallel printing fibers that mimic native tissue architecture. The development of a novel extrusion-based 3D bioprinting system using PEG-Fibrinogen has shown promising results for muscle tissue regeneration, both in vitro and in vivo.
Article
Cell Biology
Ilenia Masi, Flavia Ottavi, Danila Del Rio, Valentina Caprara, Cristina Vastarelli, Sara Maria Giannitelli, Giulia Fianco, Pamela Mozetic, Marianna Buttarelli, Gabriella Ferrandina, Giovanni Scambia, Daniela Gallo, Alberto Rainer, Anna Bagnato, Francesca Spadaro, Laura Rosano
Summary: Dissemination of high-grade serous ovarian cancer (HG-SOC) in the omentum and intercalation into a mesothelial cell (MC) monolayer depends on functional alpha 5 beta 1 integrin (Int alpha 5 beta 1) activity. This study reveals a novel interactive signaling involving beta-arrestin1 (beta-arr1), the activation of the endothelin A receptor (ETAR) by endothelin-1 (ET-1), and the activation of Int alpha 5 beta 1, which promotes tumor cells towards invasive disease. The findings suggest that ETAR/beta-arr1 may regulate the functional pathway of Int alpha 5 beta 1 and could be considered in integrin-targeting programs.
CELL DEATH & DISEASE
(2023)
Article
Cell Biology
Alessio Reggio, Francesca De Paolis, Salma Bousselmi, Felice Cicciarelli, Sergio Bernardini, Alberto Rainee, Dror Seliktar, Stefano Testa, Carmine Cirillo, Paolo Grumati, Stefano Cannata, Claudia Fuoco, Cesare Gargioli
Summary: In human dystrophies, ectopic deposition of fat and fibrous tissue from FAPs exacerbates progressive muscle wasting. LY2090314 interferes with adipogenesis and has the potential to limit FAP-derived fat infiltrates in dystrophic muscles.
DISEASE MODELS & MECHANISMS
(2023)
Article
Chemistry, Multidisciplinary
Maria Antonieta Ramirez-Morales, Elisa De Luca, Chiara Coricciati, Alberto Rainer, Giuseppe Gigli, Giuseppe Mele, Pier Paolo Pompa, Maria Ada Malvindi
Summary: This study presents a new method for the tailored synthesis of dual-color fluorescent core-shell silicon dioxide nanoparticles. The nanoparticles were functionalized with biotin to enhance their colloidal stability. Various analytical and microscopy techniques were employed to characterize the biotinylated nanoparticles. Super-resolution microscopy based on structured illumination was used to image the double-fluorescent nanoparticles at nanometric resolution. These nanoparticles have versatile potential applications in fluorescence optical nanoscopy and biomedical intracellular biosensing.
NANOSCALE ADVANCES
(2023)
Meeting Abstract
Cell & Tissue Engineering
Sara Maria Giannitelli, Manuele Gori, Miranda Torre, Pamela Mozetic, Franca Abbruzzese, Marcella Trombetta, Enrico Traversa, Lorenzo Moroni, Alberto Rainer
TISSUE ENGINEERING PART A
(2022)
Meeting Abstract
Cell & Tissue Engineering
Manuele Gori, Sara Maria Giannitelli, Andrea Zancla, Pamela Mozetic, Marcella Trombetta, Nicolo Merendino, Alberto Rainer
TISSUE ENGINEERING PART A
(2022)
Meeting Abstract
Cell & Tissue Engineering
Manuele Gori, Sara Maria Giannitelli, Rocco Papalia, Gianluca Vadala, Loredana Zollo, Alberto Rainer, Vincenzo Denaro
TISSUE ENGINEERING PART A
(2022)
Article
Chemistry, Multidisciplinary
Sara Maria Giannitelli, Emanuele Limiti, Pamela Mozetic, Filippo Pinelli, Xiaoyu Han, Franca Abbruzzese, Francesco Basoli, Danila Del Rio, Stefano Scialla, Filippo Rossi, Marcella Trombetta, Laura Rosano, Giuseppe Gigli, Zhenyu Jason Zhang, Emanuele Mauri, Alberto Rainer
Summary: This study successfully synthesized nanogels using droplet-based microfluidics, demonstrating precise control over nanoparticle size and morphology, and validated its potential application as a drug delivery system in vitro.
Meeting Abstract
Oncology
Danila Del Rio, Valentina Caprara, Ilenia Masi, Francesca Spadaro, Sara Giannitelli, Alberto Rainer, Anna Bagnato, Laura Rosano
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
