Journal
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
Volume 37, Issue -, Pages 356-362Publisher
ELSEVIER
DOI: 10.1016/j.msec.2014.01.033
Keywords
Antibacterial; Silver(I); Insensitivity UV light; Medical devices
Categories
Funding
- FONDECYT [11080133, 1100537]
- CONICYT [79090024]
- FONDAP [15130011]
- DICYT [021340AG]
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Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) were studied against Escherichia coli, Listeria monocytogenes (ISP-65-08), Salmonella typhi and Staphylococcus aureus (ATCC 25923) using kinetics of grown inhibition, viability assays, minimum inhibitory concentration and optical microscopy. The 3 silver compounds were tested toward UV-radiation in order to characterize their light insensitivity for potential medical devices: UV-radiation curable polymers. Photophysical measurements show remarkable differences toward UV-radiation, which were explained based on their polymeric structures with multiple nature bonds between pyridinedicarboxylic ligands and Ag(I) centers. We found a bacteriolytic effect and differences in the antibacterial efficiency depending on the structure of the complexes and the nature of Ag-X (X = oxygen and nitrogen) bonds: AgQuinoI > AgLutidin > AgIsocinchom. (C) 2014 Elsevier B.V. All rights reserved.
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