Article
Chemistry, Physical
Baoxiu Wang, Jiahui Li, Zhuotong Wu, Nan Sheng, Minghao Zhang, Zhiliang Han, Mengtian Jin, Jing Li, Xiangguo Lv, Kangkang Ou, Huaping Wang, Shiyan Chen
Summary: The study demonstrates the potential of using ion-channel-mimetic nanofibers/ MXene membrane as an osmotic nanopower generator with high-performance osmotic energy conversion and good biocompatibility.
Article
Biochemistry & Molecular Biology
Igor Rzhepakovsky, Sergey Piskov, Svetlana Avanesyan, Marina Sizonenko, Lyudmila Timchenko, Oxana Anfinogenova, Andrey Nagdalian, Andrey Blinov, Evgeniya Denisova, Stanislav Kochergin, Sergey Kubanov, Magomed Shakhbanov, Mohammad Ali Shariati, Mohammad S. Mubarak
Summary: Pure and porous bacterial cellulose scaffolds were synthesized using Medusomyces gisevii Sa-28 bacterial strain. Modification with gelatin increased the biocompatibility and solubility of the scaffolds. The scaffolds exhibited uniform distribution of pores, promoting new blood vessel growth and collagen fiber formation. The results suggest that these scaffolds can be used for engineering hard and soft tissues.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Karolina Dydak, Adam Junka, Grzegorz Nowacki, Justyna Paleczny, Patrycja Szymczyk-Ziolkowska, Aleksandra Gorzynska, Olga Aniolek, Marzenna Bartoszewicz
Summary: This study evaluated the suitability of bacterial cellulose and gentamicin-modified mesh adjuvants in surgical meshes and found that the modified mesh had no cytotoxic effect and effectively inhibited bacterial growth compared to non-coated mesh, suggesting that the modified mesh can be used as an effective implant in hernia surgery.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Jia Liu, Shuxia Wang, Lei Jiang, Wei Shao
Summary: Novel antimicrobial BC membranes were prepared by covalently grafting kanamycin onto regenerated bacterial cellulose (RBC) membranes. The kanamycin grafted RBC membrane displayed excellent antibacterial activity towards various microorganisms without any kanamycin leaching, and also showed good biocompatibility in MTT assay.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Materials Science, Multidisciplinary
V. M. Bergottini, D. Bernhardt
Summary: This study presents a simple procedure to transform Kombucha SCOBY membranes into cellulose nanofiber aerogels. The obtained nanofibers had a thickness ranged mainly between 50 and 110 nm, good crystallinity (90%), and thermal stability (343 oC). The simplicity of this nanofiber aerogel protocol may contribute to the development of nano-scale materials, giving higher value to this generally composted by-product.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Shuo Tang, Kai Chi, Hui Xu, Qiang Yong, Jian Yang, Jeffrey M. Catchmark
Summary: The composite hydrogel prepared using BDDE cross-linking BC and HA showed improved physical and chemical properties, demonstrating potential biomedical applications in wound care.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Tahseen Kamal, Mazhar Ul-Islam, Sher Bahadar Khan, Esraa M. Bakhsh, Muhammad Tariq Saeed Chani
Summary: The current study successfully developed BC-Cactus (BCC) composite hydrogels with impressive mechanical features and found that the composite exhibits advantages in terms of moisture absorption, metal adsorption, and biocompatibility, making it suitable for applications in medical, pharmaceutical, and environmental fields.
Article
Food Science & Technology
Eun Jo Jang, Bandana Padhan, Madhumita Patel, Jitendra Kumar Pandey, Baojun Xu, Rajkumar Patel
Summary: Antimicrobial film is a revolutionary active packaging material that preserves food quality and extends shelf life. Researchers are fortifying bacterial cellulose (BC) with various additives to improve its antimicrobial and antioxidant properties, providing benefits for the food industry to select and produce enhanced BC with improved shelf-life and other functional qualities.
Article
Polymer Science
Yadong Wu, Yunfeng Wang, Fang Wang, Yudong Huang, Jinmei He
Summary: This study introduces a PLA/BC composite scaffold prepared by 3D printing, which exhibits good mechanical properties, biocompatibility, and blood compatibility. The hydrophilicity of the scaffold can be adjusted by the amount of added PLA. The surface with regular circular pore and stripe structures promotes cell proliferation more effectively.
Article
Polymer Science
Kannan Badri Narayanan, Rakesh Bhaskar, Kuncham Sudhakar, Dong Hyun Nam, Sung Soo Han
Summary: In this study, BC hydrogel was functionalized with PDA and used in skin tissue engineering. Characterization techniques were used to investigate the formation of PDA on BC nanofibers. The BC/PDA hydrogels showed excellent tensile strength, water-wetting ability, and enhanced cell viability, making them potential biocompatible alternatives for skin tissue engineering and wound-dressing applications.
Review
Biochemistry & Molecular Biology
Shaukat Khan, Mazhar Ul-Islam, Muhammad Wajid Ullah, Youlong Zhu, Kannan Badri Narayanan, Sung Soo Han, Joong Kon Park
Summary: This review summarizes the techniques used to develop 3D bacterial cellulose (BC) scaffolds and discusses their potential biomedical applications. It provides comprehensive coverage of the idea, requirements, synthetic strategies, and current and prospective applications of 3D BC scaffolds, making it useful for researchers working with polysaccharides, biopolymers, or composite materials.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Mohammad Hadi Salehi, Hooman Golbaten-Mofrad, Seyed Hassan Jafari, Vahabodin Goodarzi, Maliheh Entezari, Mehrdad Hashemi, Soheila Zamanlui
Summary: Bacterial cellulose aerogel was successfully used as a matrix for embedding nanomaterials and polymers to form conductive composite materials. The inclusion of nano-clay and polyaniline in the aerogel led to a significant improvement in electrical conductivity and thermal stability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biotechnology & Applied Microbiology
Mazhar Ul-Islam, Furqan Ahmad, Atiya Fatima, Nasrullah Shah, Somayia Yasir, Md Wasi Ahmad, Sehrish Manan, Muhammad Wajid Ullah
Summary: In this study, a high tensile strength BC-Aloe vera gel composite was developed and characterized for potential applications in environmental and medical fields. The composite showed improved mechanical strength, water retention capabilities, metal adsorption properties, and support for cell adhesion and proliferation. These findings suggest that the developed BCA composite could have versatile applications in different fields.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Zhao Wei, Feng F. Hong, Zhangjun Cao, Sheng-Yin Zhao, Lin Chen
Summary: A novel NGF@CSNPs/OBC nanocomposite with antibacterial activity, biodegradability, and porous microstructure was successfully developed in this study; in vitro experiments showed that the nanocomposite promoted the adhesion and proliferation of Schwann cells; animal experiments showed that NGF@CSNPs/OBC as a NGC had a good repair effect on rat sciatic nerve defects.
Article
Chemistry, Applied
Shumin Zhang, Fang Ding, Ying Liu, Xuehong Ren
Summary: In this study, a biomimetic nanoreactor encapsulated self-healing hydrogel was designed to provide both antibacterial defense and hemostatic properties. The nanoreactor released (OH)· for bacteria killing in the presence of glucose, while the hydrogel exhibited excellent hemostatic capacity by absorbing glucose from blood. This design brings new insights for nanozyme-based biomedical therapies.
CARBOHYDRATE POLYMERS
(2022)
Article
Engineering, Biomedical
Emily M. dos Reis, Fernanda V. Berti, Guilherme Colla, Luismar M. Porto
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2018)
Article
Biochemistry & Molecular Biology
Renata A. N. Pertile, Xiaoying Cui, Luke Hammond, Darryl W. Eyles
Article
Materials Science, Paper & Wood
Samara S. de Souza, Fernanda V. Berti, Karla P. V. de Oliveira, Camila Q. P. Pittella, Julia V. de Castro, Catiane Pelissari, Carlos R. Rambo, Luismar M. Porto
Article
Materials Science, Multidisciplinary
Luismar Marques Porto, Silvia Machado Abreu, Derce De Oliveira Souza Recouvreux, Fernanda Viera Berti, Carlos Renato Rambo
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2019)
Article
Materials Science, Multidisciplinary
Renata S. Brum, Patricia R. Monich, Fernanda Berti, Marcio C. Fredel, Luismar M. Porto, Cesar A. M. Benfatti, Julio C. M. Souza
MATERIALS CHEMISTRY AND PHYSICS
(2019)
Article
Materials Science, Biomaterials
Domingos Lusitaneo Pier Macuvele, Guilherme Colla, Karina Cesca, Luiz F. B. Ribeiro, Cesar E. da Costa, Janaina Nones, Everton R. Breitenbach, Luismar M. Porto, Cintia Soares, Marcio Antonio Fiori, Humberto Gracher Riella
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2019)
Article
Genetics & Heredity
Asad Amanat Ali, Xiaoying Cui, Renata Aparecida Nedel Pertile, Xiang Li, Gregory Medley, Suzanne Adele Alexander, Andrew J. O. Whitehouse, John Joseph McGrath, Darryl Walter Eyles
Article
Biochemistry & Molecular Biology
Xiaoying Cui, Renata Ap. Nedel Pertile, Zilong Du, Wei Wei, Zichun Sun, Darryl W. Eyles, James P. Kesby
Summary: The dopaminergic system plays a crucial role in various brain functions, with subcortical DA development preceding cortical maturation. Dysfunctions in DA systems have been linked to neuropsychiatric disorders. Transcriptional factors and newly discovered non-coding RNAs play a crucial role in the fate of DA neurons, with HOTAIRM1 potentially having a key modulatory role in early DA neuron development.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Neurosciences
Renata Aparecida Nedel Pertile, Dylan Kiltschewskij, Michael Geaghan, Michelle Barnett, Xiaoying Cui, Murray J. Cairns, Darryl Eyles
Summary: This study found that DVD deficiency may lead to impairments in the development of dopaminergic neurons, and the upregulation of miR-181c-5p suppresses neurite outgrowth of dopaminergic neurons, providing new evidence for environmental risk factors for schizophrenia.
Article
Psychiatry
Anastasia Brandon, Xiaoying Cui, Wei Luan, Asad Amanat Ali, Renata Aparecida Nedel Pertile, Suzanne Adele Alexander, Darryl Walter Eyles
Summary: Dopaminergic dysfunction is a significant feature in the pathophysiology of schizophrenia, and multiple environmental risk factors may induce early alterations to the development of the dopaminergic system.
TRANSLATIONAL PSYCHIATRY
(2022)
Article
Biochemistry & Molecular Biology
Renata Aparecida Nedel Pertile, Rachel Brigden, Vanshika Raman, Xiaoying Cui, Zilong Du, Darryl Eyles
Summary: Vitamin D has been found to play a key role in dopaminergic neurogenesis and differentiation, and its deficiency has been linked to disorders of abnormal dopamine signalling, such as schizophrenia. This study provides further evidence of vitamin D's role in promoting dopaminergic development by increasing neurite outgrowth, branching, presynaptic protein re-distribution, dopamine production, and functional release in various in vitro models. It also suggests a potential mechanism behind the link between developmental vitamin D deficiency and schizophrenia.
JOURNAL OF NEUROCHEMISTRY
(2023)
Article
Psychiatry
Man Kumar Tamang, Asad Ali, Renata Nedel Pertile, Xiaoying Cui, Suzy Alexander, Marloes Dekker Nitert, Chiara Palmieri, Darryl Eyles
Summary: Developmental vitamin D (DVD)-deficiency is a known risk factor for autism, and recent studies also suggest the involvement of gut microbiome/gut physiology in autism. This study investigated the impact of DVD-deficiency on autism-relevant behavioral phenotypes and gut health in an animal model. The results showed that DVD-deficient rat dams displayed altered maternal care, DVD-deficient pups exhibited increased ultrasonic vocalizations and social behavior impairments as adolescents, and there were significant changes in gut microbiome, villi length, and ileal propionate levels associated with DVD-deficiency. Overall, this study provides evidence that DVD-deficiency can lead to a broader range of autism-related behavioral phenotypes and alterations in gut health.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Materials Science, Multidisciplinary
Stefani Regina Zibetti Teixeira, Emily Marques dos Reis, Giannini Pasiznick Apati, Marcia Margarete Meier, Andre Lourenco Nogueira, Michele Cristina Formolo Garcia, Andrea Lima dos Santos Schneider, Ana Paula Testa Pezzin, Luismar Marques Porto
MATERIALS RESEARCH-IBERO-AMERICAN JOURNAL OF MATERIALS
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Leticia Bins-Ely, Karma Cesca, Fernando S. Souza, Luismar Porto, Almir Spinelli, Ricardo Magini, Bruno Henriques, Julio C. M. Souza
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2019)
Article
Engineering, Chemical
Samara Silva de Souza, Julia de Vasconcellos Castro, Luismar Marques Porto
BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
(2018)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
