Review
Food Science & Technology
Jie Long, Ziying Ye, Xingfei Li, Yaoqi Tian, Yuxiang Bai, Long Chen, Chao Qiu, Zhengjun Xie, Zhengyu Jin, Birte Svensson
Summary: This review summarizes the bioactivities and applications of agar-derived oligosaccharides, as well as the recent technologies employed to improve the properties of agarase. The relationship between bioactivity and structure of the different oligosaccharides is still not fully understood and requires further research.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Computer Science, Information Systems
Jaroslav Lacik, Vlastimil Koudelka, Cestmir Vejmola, David Kuratko, Jiri Vanek, Daniel Krzysztof Wojcik, Tomas Palenicek, Zbynek Raida
Summary: This study focuses on the development of a simplified anisotropic rat head phantom and investigates the impact of anisotropic white matter on EEG source localization. The use of 3D printing technology for fabrication and the identification of areas most sensitive to neglecting anisotropy in the model are highlighted.
Article
Biochemistry & Molecular Biology
Oleksandra Dzeikala, Miroslawa Prochon, Anna Marzec, Szymon Szczepanik
Summary: Plastic waste is a major issue in modern society, and there is a need for environmentally friendly disposable materials. In this study, gelatin blends modified with polysaccharides were produced and characterized using various techniques. The addition of agarose increased the hardness, surface energy, softening point, and glass transition temperature of the blend. The addition of starch increased the softening point and glass transition temperature. Aging affected the hardness and tensile strength of both blends.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Food Science & Technology
Chengcheng Jiang, Danyang Cheng, Zhen Liu, Jianan Sun, Xiangzhao Mao
Summary: This review summarizes the methods for extracting agaro-oligosaccharides from red algae, investigates their production and bioactivities, discusses current research issues, and provides insight into future research directions.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Margaux Peixoto, Marie-Valerie Moreno, Nassim Khider
Summary: The physiology of the patient can be personalized using serious games based on data reflected through various tests. Before testing with dry electrodes, preliminary tests on a phantom are necessary, adjusting concentrations of NaCl and graphite to obtain physiological values. The anisotropy of a muscle also needs to be considered for accurate results.
Article
Energy & Fuels
Arivazhagan Sampathkumar, Sendhil Kumar Natarajan
Summary: The freshwater ecosystem is important for human well-being, but the scarcity of fresh water is a major challenge. This study explores the use of solar stills to convert seawater into potable water, with a focus on improving productivity by incorporating agar-agar fibers and micro-Phase Change Material into the absorber basin. The results show that these additions can significantly enhance the productivity and thermal efficiency of the solar still, leading to potential economic and environmental benefits.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Chemistry, Applied
Manwinder Kaur Sidhu, Felicity Whitehead, Stefan Kasapis
Summary: The diffusion kinetics of vitamin B6 from composite gels of gelatin and agarose were studied using blending law and diffusion modelling. Structural properties of the composite gels were analyzed using various techniques, including FTIR, XRD, CLSM, and small-deformation dynamic oscillation in shear. UV-vis spectroscopy was employed to study the diffusion kinetics of vitamin B6. The results showed that blending law-based diffusion theory can predict the diffusion kinetics of bioactive compounds in aqueous composite gels.
FOOD HYDROCOLLOIDS
(2023)
Article
Clinical Neurology
Varidh Katiyar, Nidhisha Sadhwani, Ravi Sharma, Vivek Tandon, Amol Raheja, Revanth Goda, Akshay Ganeshkumar, Shashwat Mishra, Kanwaljeet Garg, Francesco Prada, Shashank S. Kale
Summary: A novel agar-based phantom was developed and assessed for ultrasonography (USG)-guided brain biopsy training. The impact of multimodal training was evaluated through pretraining and posttraining trials.
WORLD NEUROSURGERY
(2022)
Article
Materials Science, Multidisciplinary
Muhammad Angga Anugrah, Sultan Ilyas, Dahlang Tahir
Summary: This study investigated the effects of various inorganic fillers on the performance of composite phantom breast with polyvinyl alcohol as a binder. Analyzing bonding characteristics, structural properties, and atomic, electronic, and absorption abilities of the composite provided insights into creating breast phantom materials. The linear attenuation coefficient of the composites showed a direct correlation with the filler used, suggesting potential for optimized breast phantom production.
MATERIALS CHEMISTRY AND PHYSICS
(2021)
Article
Biochemistry & Molecular Biology
P. -L. Lam, R. Gambari, Y. -W. Ho, W. -Y. Wong, D. K. -P. Hau, T. W. -T. Leung, P. H. -M. Leung, C. -H. Chui
Summary: This study reports the development of a safe microparticulate system using agar and gelatin as wall matrix materials for the topical delivery of corilagin to combat MRSA. The results demonstrate the potential of corilagin-loaded gelatin/agar microspheres for applicable bio-textile products to treat drug-resistant bacterial infections.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mengjia Du, Yiguo Zhao, Yin Zhang, Shifan Sun, Yapeng Fang
Summary: Agarose/fish gelatin double-network hydrogels (DNs) were fabricated and compared with beef tendons and single-network hydrogels. Increasing the concentration of fish gelatin significantly improved the mechanical strength and toughness of the DNs, while a moderate increase in agarose concentration only improved the mechanical strength. The DNs had higher hardness, water holding capacity, and lower swelling rate compared with single-network hydrogels, and showed a high correlation with beef tendons, indicating their potential as artificial food.
Article
Engineering, Biomedical
G. A. Orozco, G. Cordoba, F. Urrea, F. Casanova, J. H. Smith, J. J. Garcia
Summary: The study updated a finite element model of backflow by considering the effect of needle insertion velocity during CED infusions, and obtained the nonlinear mechanical properties of agarose solutions by fitting experimental data. Adjusting the model with additional experimental measurements, the relevance of pre-stress in the tissue surrounding the needle during CED infusions into the brain was revealed.
Article
Biochemistry & Molecular Biology
Kai Han, Que Bai, Wendong Wu, Na Sun, Ning Cui, Tingli Lu
Summary: A novel gelatin-based adhesive hydrogel was successfully prepared using mussel-inspired chemistry, showing hemostatic properties in a rat hepatic hemorrhage model. The incorporation of graphene oxide enhanced the conductivity and mechanical properties of the hydrogels, enabling successful monitoring of EMG signals and demonstrating good cytocompatibility in L929 cell experiments. These results suggest the potential application of GelDA/GO hydrogels in tissue adhesives, wound dressings, and wearable devices.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Bao-Tran Tran Pham, Hong-Nhung Thi Hoang, Chinh Dung Trinh, Quynh Thi Phuong Bui, Thanh Khoa Phung, Thuong Thi Nguyen
Summary: A novel active coating, functionalized with Ocimum gratissimum L. essential oil, was developed to improve the properties of gelatin/agarose films. The addition of essential oil enhanced mechanical, water-barrier, bactericidal, antioxidant, and UV-shielding properties. The best performance was achieved with a 5% inclusion of essential oil. The coating showed moderate antibacterial activities against various bacteria and improved the storability of avocados.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Themistoklis Boursianis, Georgios Kalaitzakis, Georgios Gourzoulidis, Apostolos Karantanas, Efrosini Papadaki, Thomas G. Maris
Summary: The study proposed a new method using a physical phantom to simulate BOLD contrast, which was successfully achieved with good reproducibility. Results confirmed the potential use of the phantom as an fMRI simulator and as a tool for studying sensitivity and specificity of BOLD sequences/algorithms.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2022)
Article
Physics, Applied
Ying Luan, Guillaume Renaud, Jason L. Raymond, Tim Segers, Guillaume Lajoinie, Robert Beurskens, Frits Mastik, Tom J. A. Kokhuis, Antonius F. W. van der Steen, Michel Versluis, Nico de Jong
APPLIED PHYSICS LETTERS
(2016)
Article
Engineering, Biomedical
Jason L. Raymond, Ying Luan, Tao Peng, Shao-Ling Huang, David D. McPherson, Michel Versluis, Nico de Jong, Christy K. Holland
PHYSICS IN MEDICINE AND BIOLOGY
(2016)
Correction
Acoustics
Kevin J. Haworth, Jason L. Raymond, Kirthi Radhakrishnan, Melanie R. Moody, Shao-ling Huang, Tao Peng, Himanshu Shekhar, Melvin E. Klegerman, Hyunggun Kim, David D. McPherson, Christy K. Holland
ULTRASOUND IN MEDICINE AND BIOLOGY
(2016)
Article
Acoustics
Kenneth B. Bader, Michael J. Crowe, Jason L. Raymond, Christy K. Holland
ULTRASOUND IN MEDICINE AND BIOLOGY
(2016)
Article
Acoustics
Kevin J. Haworth, Jason L. Raymond, Kirthi Radhakrishnan, Melanie R. Moody, Shao-Ling Huang, Tao Peng, Himanshu Shekhar, Melvin E. Klegerman, Hyunggun Kim, David D. McPherson, Christy K. Holland
ULTRASOUND IN MEDICINE AND BIOLOGY
(2016)
Article
Acoustics
Himanshu Shekhar, Nathaniel J. Smith, Jason L. Raymond, Christy K. Holland
ULTRASOUND IN MEDICINE AND BIOLOGY
(2018)
Review
Pharmacology & Pharmacy
Yanye Yang, Juan Tu, Dongxin Yang, Jason L. Raymond, Ronald A. Roy, Dong Zhang
CURRENT PHARMACEUTICAL DESIGN
(2019)
Article
Acoustics
Amanda Q. X. Nio, Alessandro Faraci, Kirsten Christensen-Jeffries, Jason L. Raymond, Mark J. Monaghan, Daniel Fuster, Flemming Forsberg, Robert J. Eckersley, Pablo Lamata
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2020)
Article
Biotechnology & Applied Microbiology
Chun Kiat Ng, Samuel L. Putra, Joseph Kennerley, Robert Habgood, Ronald A. Roy, Jason L. Raymond, Ian P. Thompson, Wei E. Huang
Summary: The study demonstrated the successful introduction of plasmids into established non-competent bacterial biofilms using ultrasound-mediated DNA delivery technique. This method allowed for expression of exogenous genes and functional effects in biofilms, enhancing their potential applications in environments, industries, and medical fields.
MICROBIAL BIOTECHNOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Valeria Grasso, Jason L. Raymond, Regine Willumeit-Roemer, James Joseph, Jithin Jose
Summary: A stable phantom that mimics the detailed morphology of a mouse has been designed, developed, and fabricated for photoacoustic imaging (PAI). The phantom includes a 3D-printed skeleton and the main abdominal organs, and is made of a copolymer-in-oil-based material. The results show that the phantom is durable, stable, and offers a realistic resemblance to the actual rodents' anatomy.
Article
Acoustics
Cherie C. Y. Wong, Jason L. Raymond, Lillian N. Usadi, Zhiyuan Zong, Stephanie C. Walton, Adam C. Sedgwick, James Kwan
Summary: Sonochemistry utilizes ultrasound to generate reactive radicals, offering a green alternative for hydrogen production, wastewater treatment, and chemical synthesis. Conventional sonochemical reactors often have design limitations resulting in low efficacy and slow reaction kinetics. A novel reactor design was constructed, creating intense localized high pressure amplitudes capable of spontaneous cavitation, leading to significantly higher hydroxyl radicals production rate and sonochemical efficiency.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Acoustics
Hisham Assi, Rui Cao, Madhura Castelino, Ben Cox, Fiona J. Gilbert, Janek Gro, Kurinchi Gurusamy, Lina Hacker, Aoife M. Ivory, James Joseph, Ferdinand Knieling, Martin J. Leahy, Ledia Lilaj, Srirang Manohar, Igor Meglinski, Carmel Moran, Andrea Murray, Alexander A. Oraevsky, Mark D. Pagel, Manojit Pramanik, Jason Raymond, Mithun Kuniyil Ajith Singh, William C. Vogt, Lihong Wang, Shufan Yang, Sarah E. Bohndiek
Summary: Photoacoustic imaging has a promising potential in clinical trials, but its adoption in healthcare systems for clinical decision making faces barriers such as education, training, and data interpretation. The International Photoacoustic Standardisation Consortium identified these barriers and developed plans to address them.
Article
Chemistry, Multidisciplinary
Cherie CY. Wong, Lu-Lu Sun, Meng-Jiao Liu, Eleanor Stride, Jason L. Raymond, Hai-Hao Han, James Kwan, Adam C. Sedgwick
Summary: We have synthesized hydroxyl-radical (OH) responsive fluorescent probes using the 3,5-dihydroxybenzyl (DHB) functionality. In the presence of OH radicals, Umb-DHB and Res-DHB showed significant increases in fluorescence emission intensities at 460 nm and 585 nm respectively. Incubating Res-DHB in HeLa cells followed by therapeutic ultrasound resulted in a significant increase in fluorescence emission intensity, allowing the monitoring of ultrasound-induced OH production in live cells.
CHEMICAL COMMUNICATIONS
(2023)
Proceedings Paper
Engineering, Electrical & Electronic
Ipshita Gupta, Amanda Q. X. Nio, Alessandro Faraci, Mehnoosh Torkzaban, Kirsten Christensen-Jeffries, Kibo Nam, Jason L. Raymond, Kirk Wallace, Mark J. Monaghan, Daniel Fuster, Robert J. Eckersley, Pablo Lamata, Flemming Forsberg
2019 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS)
(2019)
Article
Engineering, Biomedical
Jason L. Raymond, Robin O. Cleveland, Ronald A. Roy
PHYSICS IN MEDICINE AND BIOLOGY
(2018)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)