Article
Microbiology
Emerance Jessica Claire D'Assise Goma-Tchimbakala, Ilaria Pietrini, Federica Dal Bello, Joseph Goma-Tchimbakala, Stefano Lo Russo, Stefano Paolo Corgnati
Summary: This study aimed to develop bacterial consortia for oil recovery and address the issue of oil contamination worldwide. Metagenomics analysis revealed the presence of hydrocarbon degraders in LF2 soil. Three bacterial strains were isolated, and one strain showed the most potential for further bioremediation investigation. The immobilization of consortia improved the bioremediation potential, while the addition of surfactants failed to enhance crude oil degradation.
Article
Biochemistry & Molecular Biology
Sandra-Yaneth Gaitan-Jimenez, Luz-Patricia Restrepo-Sanchez, Fabian Parada-Alfonso, Carlos-Eduardo Narvaez-Cuenca
Summary: Cashew nut-shell liquid (CNSL) and its components have the potential to act as natural antioxidants, with cardols and cardanols being effective antioxidants for soybean oil.
Article
Food Science & Technology
Yijun Liu, Leshi Li, Qiuyu Xia, Lijing Lin
Summary: Cashew nut kernel oil (CNKO) was analyzed for its lipid species, composition, and relative content using UPLC-TOF-MS/MS. The physicochemical properties, functional group structure, and oxidation stability of CNKO at different pressing temperatures were characterized. The results showed that CNKO mainly consisted of oleic acid, linoleic acid, stearic acid, and palmitic acid. The pressing temperature had a significant effect on the physicochemical properties and oxidative stability of CNKO. This study provided basic data for cashew kernel processing, quality evaluation, and functional studies.
Review
Biotechnology & Applied Microbiology
Srinivasan Kandaswamy, Venkatesa Murthy Swarupa, Souvik Sur, Gautam Choubey, Yuvarajan Devarajan, Ruby Mishra
Summary: This article discusses the viability of using cashew nutshell liquid biodiesel (CNSLBD) as an alternative energy source. The findings suggest that CNSLBD has the potential to benefit both the cashew nut industry and the energy industry.
BIOTECHNOLOGY AND BIOENGINEERING
(2023)
Article
Allergy
Arnon Elizur, Michael Y. Appel, Liat Nachshon, Michael B. Levy, Naama Epstein-Rigbi, Yael Koren, Marie Holmqvist, Helena Porsch, Jonas Lidholm, Michael R. Goldberg
Summary: Cashew OIT desensitizes most cashew-allergic patients and cross-desensitizes to pistachio. Safety is similar to OIT for other foods.
Article
Agricultural Engineering
Hongwei Wu, Qing Li, Haolin Yu, Minmin Gu, Yudie Wang, Chensen Xu, Zhixin Liao
Summary: This work explores an eco-friendly approach to extracting cashew nut shell liquid (CNSL) and refining cardanol from cashew nuts produced in Hainan, China. CNS, which is usually considered waste from agricultural processing, can be extracted into valuable CNSL using solvent extraction or supercritical CO2 extraction. The composition of extracted CNSL varies with different conditions, and less polar solvents extract more CNSL. Supercritical CO2 extraction also shows superior performance in CNSL extraction as an environmentally friendly method. CNSL from Hainan cashew nuts contains a high amount of anacardic acid. The extracted CNSL can be decarboxylated and separated to obtain a mixture of cardanol consisting of four olefins with different numbers of double bonds. Cardanol can be converted to saturated cardanol and high purity cardanol monoene through catalytic hydrogenation and catalytic transfer hydrogenation, respectively. Both saturated cardanol and cardanol monoene have promising prospects due to their chemical structure.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Agriculture, Dairy & Animal Science
J. B. Costa, M. C. P. Rogerio, M. S. S. Carneiro, L. C. Muniz, E. P. Brasil, A. R. Araujo, R. M. Fontenele, N. J. M. Batista
Summary: Cashew nut meal (CNM) can be a beneficial feed supplement for lambs, increasing protein and energy intake while improving nitrogen balance. However, using CNM at levels above 7% in the total mixed ration may reduce fiber digestibility.
Article
Food Science & Technology
Weysser Felipe Candido de Souza, Fernando Azevedo de Lucena, Katia Gomes da Silva, Laesio Pereira Martins, Ruann Janser Soares de Castro, Helia Harumi Sato
Summary: Table grapes are widely consumed worldwide for their health benefits, but their perishable nature requires postharvest practices to maintain quality and shelf-life. This study optimized edible coatings using a mixture design of alginate, galactomannans, and cashew gum, which effectively reduced weight loss, maintained firmness and color, and increased phenolic compounds and antioxidant potential in 'Italia' grapes. The use of biopolymers as edible coatings shows promise as an alternative preservation method for table grapes.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Ermelinda Bloise, Maria Rosaria Lazzoi, Lucia Mergola, Roberta Del Sole, Giuseppe Mele
Summary: Cashew nut shell liquid (CNSL), a byproduct of the cashew industry, is an important natural source of phenolic compounds that can be used as an alternative to synthetic substances in various industrial applications. The unique functional groups of CNSL components allow for the design of interesting nanostructures with tunable properties for bioactive applications.
Article
Food Science & Technology
Amanda Rodrigues Leal, Ana Paula Dionisio, Fernando Antonio Pinto de Abreu, Gilleno Ferreira de Oliveira, Idila Maria da Silva Araujo, Hilton Cesar Rodrigues Magalhaes, Andressa Barbosa Leite, Emilly Kaiane Maia da Silva, Ronaldo Ferreira do Nascimento, Helio Oliveira do Nascimento, Paulo Henrique Machado de Sousa
Summary: This study assessed the impact of kernel grade on the physicochemical quality, fatty acids, and volatile compounds of cashew nut oil. The broken kernel oils showed similar or superior quality to the whole kernel oil, especially samples B3 and P3. The oils from less intact nuts showed high proportions of monounsaturated fatty acids and higher proportions of volatile compounds not derived from oxidation in sample P3. This study expands the possibility of valorizing lower commercial value cashew nuts by producing oil with adequate quality for consumption.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Energy & Fuels
Nathalia N. Oliveira, Cheila G. Mothe, Michelle G. Mothe
Summary: Anacardium occidentale, commonly known as cashew tree, is widely used for processing nuts and producing cashew gum. This study found that cashew apple bagasse can be a rich and affordable source of bioactive compounds for functional food composition. Additionally, cashew gum has various applications in the field of medicine.
BIOMASS CONVERSION AND BIOREFINERY
(2022)
Article
Energy & Fuels
Sivakumar Pandian, Patel Chintan Dahyalal, Shanker Krishna, S. Hari, Deepalakshmi Subramanian
Summary: The study found that flow improvers made from cheap, reasonable resources such as CNSL are more effective than conventional additives, as they are cost-effective and eco-friendly.
JOURNAL OF PETROLEUM EXPLORATION AND PRODUCTION TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Rohith K. Ramakrishnan, Vinod V. T. Padil, Marcela Skodova, Stanislaw Waclawek, Miroslav Cernik, Seema Agarwal
Summary: The novel conjugate biodegradable sponge based on tree gum kondagogu shows excellent selective oil/organic solvent absorption ability. With hydrophobicity and low density, it can selectively absorb oils and organic solvents up to 19-43 times its weight and exhibit good reusability. The biodegradation behavior of the sponge in waste-water sludge shows promising potential for clearing oil spills and water treatment.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Energy & Fuels
William Iheanyi Eke, Ozioma Achugasim, Joseph Ajienka, Onyewuchi Akaranta
Summary: The modified CNSL derivatives showed promising results as pour point depressants and low-temperature flow improvers for waxy crude oil, with significant reductions in pour point and viscosity of doped crude oil. Analysis of doped oil micrographs indicated modifications to wax morphology and microstructure, demonstrating the potential of biobased oilfield chemicals derived from renewables as eco-friendly alternatives to conventional pour point depressants.
PETROLEUM SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Quan Wen, Xuejiao Wang, Bingjie Liu, Lin Lu, Xiaoming Zhang, Caleb John Swing, Shuqin Xia
Summary: This study investigated the synergistic interactions between sodium alginate (SA) and xanthan gum (XG) in edible coatings and their effects on the optical appearance. The 50:50 SA-XG coating on areca nuts showed the highest gloss and spreading coefficient, indicating improved wettability. Polarized light microscopy revealed a birefringence phenomenon caused by the liquid crystal state in the coating, resulting in better optical properties. The compatibility of SA and XG was confirmed by UV-vis transmittance, Fourier transform infrared, and scanning electron microscopy. The SA-XG film had a denser microstructure due to hydrogen bonding, resulting in improved mechanical properties and water resistance. The SA-XG combination is promising for preparing edible films with improved optical properties for areca nuts.
Article
Chemistry, Applied
Antonia Carla de Jesus Oliveira, Luise Lopes Chaves, Fabio de Oliveira Silva Ribeiro, Lais Ramos Monteiro de Lima, Thaisa Cardoso Oliveira, Fatima Garcia-Villen, Cesar Viseras, Regina C. M. de Paula, Pedro Jose Rolim-Neto, Fernando Hallwass, Edson C. Silva-Filho, Durcilene Alves da Silva, Jose Lamartine Soares-Sobrinho, Monica Felts de la Roca Soares
Summary: Chemical modification of polysaccharides using microwave irradiation for the synthesis of phthalated cashew gum was investigated in this study, showing promising properties for improving the treatment of Chagas disease. The modified biopolymers were characterized for their structural and physicochemical properties, and the nanoparticles used for drug delivery systems exhibited specific characteristics such as size, zeta potential, and in vitro release behavior.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Lais Ramos Monteiro Lima, Everton Lucas de Lima Ramos, Maria Francilene Souza Silva, Fabio de Oliveira Silva Ribeiro, Jeanlex S. Sousa, Claudia Pessoa, Durcilene Alves Silva, Judith P. A. Feitosa, Haroldo C. B. Paula, Regina Celia Monteiro de Paula
Summary: In this study, aminated poly(N-isopropylacrylamide) was successfully grafted onto oxidized galactomannan polysaccharide from Delonix regia via Schiff base reaction. The self-organizing ability of the obtained nanoparticle copolymers was investigated, showing promising potential for drug delivery with good cell viability and transition temperature close to human body temperature. The use of free aldehyde groups in the oxidized polysaccharide for pro-drug formation with substances possessing NH2 groups was also highlighted.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Materials Science, Multidisciplinary
Bruno Peixoto de Oliveira, Flavia Oliveira Monteiro da Silva Abreu
Summary: Carbon dots (CDs) are a novel class of fluorescent nanomaterials with various beneficial properties, and the synthesis of CDs using waste materials has attracted significant interest among researchers.
Article
Biochemistry & Molecular Biology
Thaisa Cardoso de Oliveira, Antonia Carla de Jesus Oliveira, Yuri Basilio Gomes Patriota, Luise Lopes Chaves, Fabio de Oliveira Silva Ribeiro, Regina C. M. de Paula, Edson Cavalcanti Silva-Filho, Durcilene Alves da Silva, Monica Felts de La Roca Soares, Jose Lamartine Soares-Sobrinho
Summary: A new hydrophobic polymer based on angico gum (AG) was developed, and new nanoparticles were produced to expand the applications of natural polysaccharides in nanomedicine. By utilizing Plackett-Burman's experimental design, nanoparticles with different characteristics were successfully produced. NVP-loaded PAG nanoparticles showed significant promotion of drug release.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Multidisciplinary
Camila M. A. C. Alves, Flavia O. M. S. Abreu, Rinaldo S. Araujo, Mona Lisa M. Oliveira
Summary: Siloxanes are common industrial compounds found in daily products. When they enter sewage and waste treatment systems, they can increase the concentration of siloxanes in biogas and form other compounds like SiO and SiO2 during combustion, leading to increased wear and maintenance downtime of engine components. Various methods for removing siloxanes have been proposed in the literature, with activated carbon being the most commonly used method, but there are limitations in its industrial application.
Article
Chemistry, Physical
Maria K. S. O. Abreu, Maria A. S. Silva, Dieric S. Abreu, Ana R. Richter, Regina C. M. de Paula, Vera R. L. Constantino, Igor F. Vasconcelos, Francisco G. S. de Oliveira, Acacio S. de Melo, Marcio A. Correa, Izaura C. N. Diogenes
Summary: This study improves the colloidal stability of CoFe2O4 in water media by encapsulating it in CMCG. The results show that after encapsulation, CoFe2O4 forms a polymer-caged MNPs aggregate with a negatively charged layer. Despite the dilution effect of CMCG, the material maintains magnetization.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Polymer Science
Roberta Bussons Rodrigues Valerio, Nilvan Alves da Silva, Jose Ribamar Paiva Junior, Anderson Valerio Chaves, Bruno Peixoto de Oliveira, Nagila Freitas Souza, Selene Maia de Morais, Jose Cleiton Sousa dos Santos, Flavia Oliveira Monteiro da Silva Abreu
Summary: Cardanol, the main constituent of technical cashew nut shell liquid, was encapsulated in nanoparticles using biocompatible and stable polysaccharide systems to enhance its antioxidant potential, demonstrating better protection and targeted activities in various sectors such as pharmaceutical, nutraceutical, and biomedical.
Proceedings Paper
Polymer Science
Flavia Oliveira Monteiro da Silva Abreu, Micaele Ferreira Lima, Bruno Peixoto de Oliveira, Mayrla Rocha Lima, Jose Vilemar de Araujo Filho, Antonia Aniellen Raianne Moises Aguiar, Wesley Lyeverton Correia Ribeiro
Summary: In this study, carboxymethylated xanthan gum (CXG) was synthesized and characterized, and oil-in-water xanthan gum-based nanoemulsions enriched with eugenol were prepared. The nanoemulsions showed ovicidal activity against Haemonchus contortus.
MACROMOLECULAR SYMPOSIA
(2022)
Article
Biochemistry & Molecular Biology
Fabio de Oliveira Silva Ribeiro, Fatima de Cassia Evangelista de Oliveira, Claudia Pessoa, Jhones do Nascimento Dias, Patricia Albuquerque, Edymilais da Silva Sousa, Sidney Goncalo de Lima, Lais Ramos Monteiro de Lima, Venicios G. Sombra, Regina Celia Monteiro de Paula, Even Herlany Pereira Alves, Daniel Fernando Pereira Vasconcelos, Darllan Damasceno Fontenele, Bruno Iles, Jand Venes Rolim Medeiros, Alyne Rodrigues de Araujo, Durcilene Alves da Silva, Jose Roberto de Souza de Almeida Leite
Summary: Lemon gum (LG) was isolated and characterized from Citrus x latifolia in Brazil. The biocompatibility of LG was evaluated in vitro and in vivo, and it showed antiproliferative activity against human prostate adenocarcinoma cancer cells. The results indicate the potential of LG for biomedical and biotechnological applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Oncology
Raimundo Fernandes de Araujo Junior, George A. Lira, Timo Schomann, Romulo S. Cavalcante, Natalia Feitosa Vilar, Regina Celia Monteiro de Paula, Raelle Ferreira Gomes, Chih Kit Chung, Carla Jorquera-Cordero, Olena Vepris, Alan B. Chan, Luis J. Cruz
Summary: This study investigates the down-regulation of interaction between tumour-associated macrophages (TAMs) and colorectal cancer cells by nanoparticles (NPs) loaded with retinoic acid (RA) and coated with cholesterol (CHO), in combination with an anti-PD-L1 immune checkpoint inhibitor. The IL-10R/IL-10 axis is shown to overstimulate the STAT3 pathway and downregulate the NF-kappa B signalling pathway, leading to immunosuppression and epithelial-mesenchymal-transition of colorectal cancer. The use of RA-loaded NPs coated with CHO and anti-PD-L1 is found to be more effective in blocking this signalling pathway.
TRANSLATIONAL ONCOLOGY
(2023)
Article
Polymer Science
Francisco das C. M. Brito, Wilton C. Lopes, Fabio O. S. Ribeiro, Raiza Raianne Luz Rodrigues, Klinger Antonio da Franca Rodrigues, Fabricio dos Santos Machado, Ana Jersia Araujo, Jose Delano Barreto Marinho Filho, Antonia Carla J. Oliveira, Edson C. S. Filho, Irisvan S. Ribeiro, Regina C. M. de Paula, Fernando Hallwass, Vicente Galber F. Viana, Durcilene A. Silva
Summary: This study modified the cashew gum through an amine reaction, which changed its molecular weight and surface charge. The amine group binding to the gum was confirmed, and cytotoxicity tests showed that the modified gum had increased thermal stability and no cytotoxic potential at concentrations below 50.0 mg/L.
Article
Chemistry, Multidisciplinary
Aline T. dos Santos, Emerson L. da Silva, Raquel C. Montenegro, Jeanlex S. de Sousa, Regina C. M. de Paula, Judith P. A. Feitosa
Summary: Copolymers of N-isopropylacrylamide (NIPAm) grafted with Dextran sulfate (DS) hold great potential for drug release, especially in targeted delivery to inflamed regions. Two different ratios of the copolymers were synthesized and confirmed using spectroscopic techniques. These copolymers demonstrated self-organization behavior in aqueous medium at temperatures above 34°C, with sizes smaller than 300 nm and spherical shapes. DS-g-3PNIPAm showed specificity to leukemic cells without affecting normal cell proliferation. Encapsulating and delivering the poorly water-soluble drug MTX using DS-g-3PNIPAm can overcome its severe side effects and improve bioactivity and stability. Among the thermo-responsive copolymers and targeted MTX nanocarriers, the DS-g-PNIPam exhibited the best performance.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Ana R. Richter, Jose G. Veras-Neto, Jeanlex S. Sousa, Josilayne F. S. Mendes, Raquel O. S. Fontenelle, Stephanie A. N. M. Silva, Jose D. B. Marinho-Filho, Ana J. Araujo, Judith P. A. Feitosa, Haroldo C. B. Paula, Francisco M. Goycoolea, Regina C. M. de Paula
Summary: This study reports the effect of acyl chain length on hydrophobized cashew gum derivatives. By using different anhydrides, the properties of nanoparticles and drug delivery were investigated, resulting in nanoparticles with desirable properties.
COLLOIDS AND INTERFACES
(2022)
Article
Chemistry, Applied
Lais R. M. Lima, Clara M. W. S. A. Cavalcante, Maria J. M. Carneiro, Josilayne F. S. Mendes, Nayara A. Sousa, Rosimeyre S. Freire, Vicente P. T. Pinto, Raquel O. S. Fontenelle, Judith P. A. Feitosa, Regina C. M. de Paula
Summary: Thermo-responsive copolymers were synthesized for loading galactomannan and antifungal drug amphotericin-B, showing good hemocompatibility and controlled release profile. The copolymer nanoparticles demonstrated effective antifungal activity with improved hemocompatibility compared to commercial amphotericin-B.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS
(2021)
Article
Polymer Science
Carlos Pinheiro Chagas de Lima, Andreia Hansen Oster, Fabio Rossi Cavalcanti, Regina Celia Monteiro de Paula, Judith Pessoa Andrade Feitosa
Summary: The study showed that sulfated chicha gum (SCHG) can act as an effective elicitor, enhancing the activity of guaiacol peroxidase and polyphenol oxidases while increasing the lignin content in apple fruits. Plant exudate may serve as an abundant, renewable, and safe source of elicitors.
POLIMEROS-CIENCIA E TECNOLOGIA
(2021)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
