Article
Thermodynamics
Josue da Silva Buriti, Maria Eduarda Vasconcelos Barret, Francivandi Coelho Barbosa, Bruna Michele Arruda de Brito Buriti, Jose William de Lima Souza, Hermano de Vasconcelos Pina, Patricia de Luna Rodrigues, Marcus Vinicius Lia Fook
Summary: This study synthesized pure and silver-doped bioglasses using the sol-gel method, developed chitosan/45S5-Ag biocomposites, and evaluated their performance. The silver-doped bioglasses showed enhanced antibacterial activity and biodegradability without cytotoxicity, making them suitable for tissue regeneration.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2021)
Article
Materials Science, Ceramics
B. Degraeve, B. Lefeuvre, N. Rocton, N. Herbert, N. Hamrouni, G. Hauss, A. Largeteau, M. Prakasam, H. Oudadesse, O. Merdrignac-Conanec
Summary: Porous bioglass monoliths were prepared by hydrothermal hot pressing, and it was found that sol-gel derived monoliths showed higher kinetics in the development of an apatite layer. Hydrothermal hot pressing can also be used for processing 3D bioglass structures with porosity gradient.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Ananthakrishnan Nitu, Ananthakrishnan Srinivasan
Summary: Magnetic interactions in sol-gel-derived bioactive magnetic glass-ceramics (MGCs) were studied using EPR, magnetic susceptibility, and magnetization techniques. The intensity and linewidth of resonance absorptions showed composition dependence. Dipolar interaction dominated in MGC samples with iron oxide content ≤ 4 wt.%, while a crossover to super-exchange interaction occurred in samples with higher iron oxide content. The magnetic behavior differed between MGC samples with iron oxide content ≤ 6 and ≥ 8 wt.%, with the latter exhibiting superparamagnetic behavior correlated with the percentage of magnetic phases present.
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
(2023)
Article
Engineering, Biomedical
Soo Bin Im, Garima Tripathi, Thi Thao Thanh Le, Byong Taek Lee
Summary: The study evaluated an injectable bone substitute system utilizing porous bioglass-derived granules supplemented with hyaluronic acid, showing excellent bioactivity in in vitro and in vivo experiments by promoting cell adhesion, proliferation, and fast bone formation after implantation. The system also facilitated tissue repair and regeneration, preventing scatter of BG granules and increasing resorption for bone tissue regeneration.
BIOMEDICAL MATERIALS
(2021)
Article
Materials Science, Ceramics
Gianmarco Taveri, Ondrej Hanzel, Jaroslav Sedlacek, Jaromir Tousek, Zuzana Nescakova, Martin Michalek, Ivo Dlouhy, Miroslav Hnatko
Summary: A new procedure was developed to consolidate Bioglass(R) 45S5 powder in water-based solutions, resulting in nearly fully dense samples with hydroxyapatite formation observed in simulated body fluid immersion. Analysis of microstructure and chemistry differences between the base material and dissolution product suggest potential applications of the densified Bioglass(R) in bio-engineering.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
Ehsan Vafa, Reza Bazargan-Lari, Mohammad Ebrahim Bahrololoom
Summary: This study compared two different types of 45S5 bioactive glass-ceramic prepared with two different catalysts, and found that the Homemade Vinegar Catalyzed Bioactive Glass (HMVCBG) had more uniformity, larger specific surface area, and higher bioactivity levels compared to the traditional nitric acid catalyzed bioactive glass.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2021)
Article
Polymer Science
Cristina-Daniela Ghitulica, Andrada-Ioana Damian-Buda, Andreia Cucuruz, Georgeta Voicu
Summary: In this study, bioglasses were synthesized from the ZnO(MgO)-CaO-SiO2-P2O5 system using the sol-gel method, and the results demonstrated enhanced interaction with simulated body fluid for samples containing magnesium and reduced mineralization for samples containing zinc. Incorporating different ionic species Zn2+ and Mg2+ in the bioglass composition was found to significantly enhance biocompatibility and antibacterial properties.
Article
Dentistry, Oral Surgery & Medicine
Humberto Palza Cordero, Rene Castro Cid, Mario Diaz Dosque, Rodrigo Cabello Ibacache, Patricia Palma Fluxa
Summary: The study evaluated the effects of pure bioglass and bioglass doped with lithium ions on oral diseases, demonstrating their ability to promote tooth remineralization and inhibit the growth of caries and periodontitis pathogens. The presence of lithium enhanced the antibacterial effect against A. actinomycetemcomitans compared to pure bioglass.
JOURNAL OF DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Humberto Palza Cordero, Rene Castro Cid, Mario Diaz Dosque, Rodrigo Cabello Ibacache, Patricia Palma Fluxa
Summary: Pure BG and BGLi have shown to promote partial remineralization of enamel teeth, inhibit the growth of S. mutans and P. gingivalis, and exhibit higher toxicity against A. actinomycetemcomitans, with BGLi showing better inhibitory effects.
JOURNAL OF DENTISTRY
(2021)
Article
Chemistry, Physical
Peter Adam, Marius Horvath, Katalin Sinko
Summary: The main aim of this research was to develop a new low-cost synthesis route for producing ultralight Al2O3 cryogel - fiber composite materials for high temperature insulation. The Al2O3 fibers act as the matrix in these composites instead of the typical reinforcement phase. The synthesis of precursor systems involves sol-gel chemistry, with the same starting materials used for both types of porous Al2O3 systems. The composite systems were characterized using various tests and analysis techniques.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Materials Science, Multidisciplinary
Zhi Wei Loh, Mohd Hafiz Mohd Zaid, Mohd Mustafa Awang Kechik, Yap Wing Fen, Khamirul Matori Amin, Wei Mun Cheong
Summary: This study designed a bioactive glass using waste to improve mechanical properties while maintaining bioactivity performance in vitro. The novel bioactive glasses were prepared using the melt-quenching approach and their bioactivity characteristics were evaluated using phosphate buffer saline as an immersion medium. The results showed that sample 0F had a carbonate apatite phase, while sample 3F had a fluorapatite and calcite phase, supported by the FTIR spectra. The pH also increased for both samples, indicating their bioactivity. Additionally, sample 3F exhibited higher hardness and toughness, supported by the weight gained in the biodegradability analysis. This work offers a promising technique to fabricate bioactive glass incorporating waste for potential dental applications.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Engineering, Biomedical
Justin J. Chung, Jin Yoo, Brian S. T. Sum, Siwei Li, Soojin Lee, Tae Hee Kim, Zhenlun Li, Molly M. Stevens, Theoni K. Georgiou, Youngmee Jung, Julian R. Jones
Summary: Inorganic-organic hybrid biomaterials made with star polymer and silica are successfully 3D printed as bone substitutes, showing promising mechanical properties. The hybrid scaffolds are able to promote osteoblast cell adhesion in vitro and demonstrate osteogenic and angiogenic properties in a rat model.
ADVANCED HEALTHCARE MATERIALS
(2021)
Article
Materials Science, Ceramics
Shadpour Mallakpour, Mina Naghdi
Summary: A bone scaffold was fabricated using a hybrid of TiO2@LDH to leverage the advantages of both nanostructures, with LDH providing a suitable bed for TiO2 nanoparticles and Alg embedding them for stability. The scaffold showed excellent biomineralization and antibacterial properties, making it a promising candidate for bone tissue engineering.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Lilian de Siqueira, Tiago M. B. Campos, Samira E. A. Camargo, Gilmar P. Thim, Eliandra S. Triches
Summary: This study investigated the crystallization process of two bioglass series containing niobium derived from 45S5, revealing the crucial role of the breakdown of Si-O-Si bonds and the formation of Si-O-NBO bonds in biological responses. XRD and DSC analysis provided insights into the structural changes in the glasses, marking a significant contribution to the understanding of bioactive materials.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2021)
Article
Materials Science, Ceramics
Maria Chromcikova, Roman Svoboda, Beata Pecusova, Branislav Hruska, Miroslava Hujova, Aleksandra Nowicka, Marek Liska
Summary: Differential scanning calorimetry, thermomechanical analysis and Raman spectroscopy were used to investigate the structural relaxation phenomena in Li-doped 45S5 Bioglass with the presence of Li2O and P2O5 oxides. The study revealed similar glass transition behavior for the enthalpy and volume manifestations of relaxation motions. The Tool-Narayanaswamy-Moynihan (TNM) model was applied and the simulation-comparative methodology was used to determine the model relaxation parameters. The results showed no significant correlation between the TNM model parameters and the synthesized glass composition. However, a strong correlation was found between various physico-chemical properties related to glass transition kinetics and the content of Q(Si)(2) species responsible for chain-like structure formation in the glass.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2022)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
