Journal
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
Volume 28, Issue 7, Pages 1117-1122Publisher
ELSEVIER
DOI: 10.1016/j.msec.2007.05.006
Keywords
NiTi alloy; calcium phosphates coating; biocompatibility; cell cultures
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Funding
- National Nature Science Foundation of China [50471048]
- Education Ministry, China
- Specialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [20040056016]
- Municipal Science and Technology Commission, Tianjin, China [043803311]
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The nearly equi-atomic nickel titanium alloy was coated with calcium phosphates by socking the chemically treated alloy in simulated body fluid in order to prepare bioactive NiTi implants. The biocompatibility of the calcium phosphates coated NiTi alloy was investigated by in vitro 3T3 human embryonic fibroblast cell culture tests. The cells attachment and morphologies were studied using phase contrast light microscope and environmental scanning electron microscope. The mechanically polished and the calcium phosphates coated NiTi samples were well tolerated by the cells, whereas, the controlled pure Ni samples exhibited strong toxicity to the cells. Furthermore, the calcium phosphates coated NiTi samples showed good osteoconductivity. (c) 2007 Elsevier B.V. All rights reserved.
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