Article
Biochemistry & Molecular Biology
Emma N. Taylor, Manfred Beckmann, Bernardo Villarreal-Ramos, Hans-Martin Vordermeier, Glyn Hewinson, David Rooke, Luis A. J. Mur, Ad P. Koets
Summary: This study compared the metabolite profiles of subclinically infected Holstein-Friesian heifers with antibody binding to selected MAP antigens. Using metabolomics, 33 differentially accumulated metabolites were identified in naturally MAP-infected heifers compared to controls, with five significantly elevated throughout the study. These findings suggest the potential of metabolomics in identifying novel MAP diagnostic markers and understanding the bovine immune response to MAP.
Article
Multidisciplinary Sciences
Ewa Monika Drzewiecka, Wiktoria Kozlowska, Agata Zmijewska, Anita Franczak
Summary: This study revealed that dietary restriction during the peri-conceptional period causes changes in gene expression in the pig myometrium, particularly those involved in endocrine activity, embryo-maternal interactions, and the regulation of cell cycle and proliferation.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Emma N. Taylor, Jiwan Han, Congying Fan, Manfred Beckmann, Glyn Hewinson, David Rooke, Ad P. Koets, Luis A. J. Mur
Summary: In this study, longitudinal metabolomic changes in Holstein-Friesian (HF) heifers from birth to sexual maturity were assessed. The findings suggest the importance of acetic acid and 3-phenylpropionate (3-PP) in rumen development and growth, and the elevation of fatty acyls in response to post-weaning stress-induced innate immune response. This research provides valuable information for the nutrition and healthy development of heifers.
Article
Immunology
Wen-Heng Ji, Dan-Dan Li, Dan-Ping Wei, Ai-Qin Gu, Ying Yang, Jing-Pian Peng
Summary: The study shows that CYP26A1 plays a significant role in regulating the polarization of uterine macrophages to M1, and deficiency of CYP26A1 can lead to insufficient M1 polarization during the peri-implantation period, affecting blastocyst implantation.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Veterinary Sciences
Emma N. Taylor, Manfred Beckmann, Glyn Hewinson, David Rooke, Luis A. J. Mur, Ad P. Koets
Summary: This study identified biomarkers for MAP infections using metabolomic approach and highlighted the role of fatty acyls and fatty acid metabolism pathway. The results demonstrate the validity of metabolomic approach in studying MAP infections.
VETERINARY RESEARCH
(2022)
Article
Agriculture, Dairy & Animal Science
H. E. Flay, C. B. Reed, B. Kuhn-Sherlock, C. V. C. Phyn, C. R. Burke, S. Meier, I. J. Clarke
Summary: Previous research has found that Holstein-Friesian dairy heifers with positive genetic merit for fertility traits reach puberty earlier than those with negative genetic merit. This study investigated the functionality of the hypothalamus-pituitary-gonadal (HPG) axis in peripubertal heifers with divergent genetic merit, finding that the earlier onset of puberty in positive heifers is associated with earlier activation of the HPG axis.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Luca Turini, Giuseppe Conte, Francesca Bonelli, Alessio Madrigali, Brenno Marani, Micaela Sgorbini, Marcello Mele
Summary: The study aimed to estimate heifers' weight based on body measurements, building equations for weight estimation at crucial growing times with three variables or fewer needed. The models were found to be statistically significant and capable of field application, with future studies potentially modifying the equations based on different growth rate targets.
Article
Multidisciplinary Sciences
Seungmin Ha, Seogjin Kang, Manhye Han, Jihwan Lee, Hakjae Chung, Sang-Ik Oh, Suhee Kim, Jinho Park
Summary: The blood parameters tested on the calving date are associated with the development and severity of ketosis during the postpartum transition period in dairy cows, serving as potential indicators to identify cows susceptible to ketosis.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Ewa Monika Drzewiecka, Wiktoria Kozlowska, Agata Zmijewska, Pawel Jozef Wydorski, Anita Franczak
Summary: Electromagnetic fields can alter the expression levels of CYP19A3 and HSD17B4 in pig myometrium during the peri-implantation period, while progesterone may mitigate the effects of EMF, regulating the expression levels of aromatase.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Endocrinology & Metabolism
Runan Hu, Yanjing Huang, Yufan Song, Xiao Wu, Kunkun Song, Guangying Huang, Mingmin Zhang, Haoxu Dong
Summary: This study aimed to investigate the effect of acupuncture on improving the pregnancy rate of COH rats by regulating the opening time of the implantation window and endometrial receptivity. Acupuncture was performed on COH rats at specific acupoints for 7 times. The results showed that acupuncture significantly increased the pregnancy rate, restored abnormal hormone levels, and reversed the advancement of implantation window in COH rats. Additionally, acupuncture restored the expression levels of ER, PR, LIF, integrin beta 3, VEGF, and FGF-2 in the endometrium to varying degrees. Therefore, acupuncture may enhance endometrial receptivity and improve the pregnancy rate of COH rats.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Microbiology
Masaki Maezawa, Yuki Fujii, Masataka Akagami, Junko Kawakami, Hisashi Inokuma
Summary: In this study, BoLA-DRB3 genotyping was performed in 59 EBL cattle younger than 3 years and 69 EBL cattle older than 3 years. The BoLA-DRB3*15:01 allele was identified as a susceptibility allele for early EBL onset. The BoLA-DRB3*15:01/*15:01 and BoLA-DRB3*15:01/other genotypes were found to be early EBL onset susceptibility genotypes.
VETERINARY MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Yuta Matsuno, Kazuya Kusama, Kazuhiko Imakawa
Summary: This study characterized the expression profile of lncRNAs during peri-implantation periods in sheep conceptuses. The analysis identified a total of 8808 lncRNAs, including 3423 novel lncRNAs. Gene ontology analysis revealed enrichment of lncRNA target genes in the respiratory electron transport chain (RETC). The findings suggest that lncRNAs may play a role in regulating RETC during conceptus development in sheep.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2022)
Article
Agriculture, Dairy & Animal Science
Davut Koca, Yavuz Nak, Sait Sendag, Deniz Nak, Talha Avcilar, Mustafa Eren Sahin, Talha Arslan, Musa Ozgur Ozyigit, Axel Wehrend
Summary: The effects of exogenous Vit D3 treatment on serum AMH concentrations in Holstein Friesian heifers were evaluated. The results showed that exogenous Vit D3 did not affect serum AMH levels in these heifers.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Agriculture, Dairy & Animal Science
Panagiota Kazana, Nektarios Siachos, Nikolaos Panousis, Anatoli Petridou, Vasilis Mougios, Georgios E. Valergakis
Summary: This study found a significant phenotypical variability among calves in rumen parameters, with management factors such as age, body weight, group housing, and late forage feeding affecting ruminal VFA concentrations and pH values. Feeding 7-8 L of milk replacer daily did not affect the smooth transition, regardless of weaning method.
Article
Agriculture, Dairy & Animal Science
Zenon Nogalski, Dariusz Piwczynski, Anna Nogalska
Summary: This study aimed to assess the clinical applicability of measuring maternal intrapelvic area and selected morphometric parameters before parturition in predicting dystocia in dairy heifers. The results showed that these measurements were closely related to calving difficulty and could be used for dystocia prediction.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
