Article
Environmental Sciences
Na Yao, Yaqun Zhang, Yangzhen Li, Yuanri Hu, Hengde Li
Summary: In this study, genomic markers in Chinese tongue sole were identified and their association with hypermelanosis area was analyzed. Hypermelanosis was found to be a complicated quantitative trait with a certain degree of predictability, indicating the existence of complex genetic mechanisms.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Fisheries
Wenwen Wang, Qian Xu, Xinbao Liu, Hongning Liu, Zhujun Li, Qingxin Fan, Suxu Tan, Kunpeng Shi, Yanting Xia, Zhenxia Sha
Summary: This study explored the relationship between bacterial concentrations and host mortality, inflammatory reaction, and immune response in half-smooth tongue sole after infection with Vibrio anguillarum. The results indicated that the 24-48 hour period post-infection was a key time node for early detection and intervention of vibriosis. Excessive activation of the complement system and inflammatory reaction may contribute to mass death in fish.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Yangzhen Li, Yuanri Hu, Yingming Yang, Jiayu Cheng, Xiangming Cheng, Songlin Chen
Summary: Genetic variation for phenotypic female proportion (FP) in tongue sole has been confirmed, with moderately positive genetic correlations between FP and growth traits, indicating the feasibility of joint improvement through selective breeding.
Article
Fisheries
Chunguang Gong, Yaotong Hao, Yating Liu, Yaxian Zhao, Yufeng Liu, Guixing Wang, Zhongwei He, Jiaqi Liu, Bo An, Yanling Zhang, Qinghai Yu, Yufeng Wang, Jilun Hou
Summary: The study found that the immune system of the half-smooth tongue sole is not sensitive to moderate- or low-dose Vibrio vulnificus infection, while leukocytes, ALP, and complement primarily play a role in resisting high-dose infection. A variety of intestinal microbial taxa are important in inhibiting Vibrio vulnificus growth.
Article
Microbiology
Yaotong Hao, Yaxian Zhao, Yitong Zhang, Yufeng Liu, Guixing Wang, Zhongwei He, Wei Cao, Tian Han, Xun Zhang, Ziying Zhang, Yufen Wang, Chunguang Gong, Jilun Hou
Summary: This study investigated the intestinal microbial response to different doses of Vibrio alginolyticus infection in half-smooth tongue sole. The results showed that high-dose infection significantly altered the intestinal microbiota, decreased microbial diversity, and increased the number of potential pathogens such as Vibrio and Shewanella.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Hongning Liu, Suxu Tan, Yadong Chen, Xuejie Chen, Xinbao Liu, Zhujun Li, Ningning Wang, Sen Han, Zhendong Wu, Jie Ma, Kunpeng Shi, Wenwen Wang, Zhenxia Sha
Summary: This study elucidated the regulatory mechanism of Cse-miR-722 on CsC5aR1 and demonstrated its important role in immune response.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Fisheries
Yating Liu, Yaotong Hao, Yufeng Liu, Guixing Wang, Zhongwei He, Yaxian Zhao, Zixiong Xu, Xiaochen Liu, Yufeng Wang, Chunguang Gong, Jilun Hou
Summary: The study highlights the important role of atp6v0b in the response of half-smooth tongue sole to Vibrio vulnificus infection, indicating its crucial role in regulating the immune response.
AQUACULTURE REPORTS
(2021)
Article
Fisheries
Lei Wang, Fumiao Zhang, Yadong Chen, Shuangyan Wang, Zhangfan Chen, Qian Zhou, Songlin Chen
Summary: In this study, the membrane-bound and secretory IgT of the half-smooth tongue sole were identified for the first time. Transcript levels of IgT showed significant induction upon Vibrio Harveyi infection. This study provides insights into the immune response of marine fish.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Genmei Lin, Dong Gao, Jianguo Lu, Xiaowen Sun
Summary: This study investigated the gene expression patterns during gonad differentiation in the half-smooth tongue sole, revealing differentially expressed genes associated with sex differentiation and gonad development. Trend analysis showed that gene expression patterns varied over time, with either common features or significant sexual dimorphism. Transcript structure analyses identified both sex and time differences among samples, clarifying the significant sexual differences during early development and providing insight into sex differentiation and development mechanisms.
MARINE BIOTECHNOLOGY
(2021)
Article
Endocrinology & Metabolism
Bin Wang, Kaijie Wang, Zhenfang Tian, Aijun Cui, Xin Liu, Zhixin Jin, Xuezhou Liu, Yan Jiang, Yongjiang Xu
Summary: This study evaluated the effects of endogenous SPX2 peptide on the expression levels of key reproductive genes in the brain-pituitary axis of half-smooth tongue sole. The results showed that SPX2 has inhibitory effects and can induce an increase in pituitary fsh beta expression.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Tingting Zhang, Mengqian Zhang, Yuxuan Sun, Lu Li, Peng Cheng, Xihong Li, Na Wang, Songlin Chen, Wenteng Xu
Summary: This study identified six Csfoxo members that play important roles in the male differentiation process of Chinese tongue sole. The expression of these genes is regulated by C/EBP alpha and c-Jun transcription factors. Knockdown experiments confirmed the significance of these genes in sex differentiation and spermatogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Jiazhou Tong, Xiaolu Guan, Shuai Jiang, Li Sun
Summary: This study identified a SAP domain-containing protein, CsSDP, in half-smooth tongue sole, which has immune modulation effects and inhibits bacterial growth by disrupting the bacterial cell wall.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Xianghui Zhang, Xiancai Hao, Wenxiu Ma, Tengfei Zhu, Zhihua Zhang, Qian Wang, Kaiqiang Liu, Changwei Shao, Hong-Yan Wang
Summary: This study analyzed the gene expression changes in the kidney of Chinese tongue sole after Vibrio harveyi infection and found rapid up-regulation of immune-related pathways in the early stage, as well as a close connection between the immune system and neuroendocrine system.
Article
Fisheries
Xiaoqin Fu, Yadong Chen, Lei Wang, Qian Zhou, Ming Li, Yu Song, Yangzhen Li, Fazhen Zhao, Songlin Chen
Summary: In this study, a perforin homologue CsPRF1l was identified in half smooth tongue sole, showing higher expression in the intestine and significant upregulation in liver, spleen, kidney, intestine, gills and skin after V. harveyi challenge. The recombinant CsPRF1l protein exhibited antimicrobial activity against V. harveyi, suggesting its potential therapeutic application for V. harveyi infection in fish.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Fisheries
Bin Wang, Aijun Cui, Yaxing Zhang, Yongjiang Xu, Weixin Wang, Yan Jiang, Xuezhou Liu
Summary: This study reveals the existence of the tac3 gene in a flatfish species, suggesting its potential involvement in the control of reproduction in the half-smooth tongue sole. The tac3 gene was found to be highly expressed in the brain, intestine, and gonads of both sexes, with the highest levels observed in the hypothalamus. Additionally, the expression of tac3 mRNA in the pituitary and ovary varied during ovarian maturation, indicating a potential role in the reproductive process.
AQUACULTURE REPORTS
(2021)
