Recognition of LPS by TLR4: Potential for Anti-Inflammatory Therapies

Unique Structural Modifications Are Present in the Lipopolysaccharide from Colistin-Resistant Strains of Acinetobacter baumannii

(2013) Mark R. Pelletier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Eritoran, an Antagonist of MD2-TLR4, on Mortality in Patients With Severe Sepsis

(2013) Steven M. Opal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Marine Compounds with Therapeutic Potential in Gram-Negative Sepsis

(2013) Tamara Solov'eva et al.   Marine Drugs

Selection, synthesis, and anti-inflammatory evaluation of the arylidene malonate derivatives as TLR4 signaling inhibitors

(2012) Shuting Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Arsenic trioxide prevents nitric oxide production in lipopolysaccharide -stimulated RAW 264.7 by inhibiting a TRIF-dependent pathway

(2012) Miyuki Takahashi et al.   CANCER SCIENCE

Pseudoalteromonas strains are potent immunomodulators owing to low-stimulatory LPS

(2012) Kristina Maaetoft-Udsen et al.   Innate Immunity

Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3

(2012) B. W. Bardoel et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS

(2012) K. Gomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists

(2011) Francesco Peri et al.   BIOTECHNOLOGY ADVANCES

From agonist to antagonist: Structure and dynamics of innate immune glycoprotein MD-2 upon recognition of variably acylated bacterial endotoxins

(2011) Mari L. DeMarco et al.   MOLECULAR IMMUNOLOGY

Pseudomonas Evades Immune Recognition of Flagellin in Both Mammals and Plants

(2011) Bart W. Bardoel et al.   PLoS Pathogens

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

(2009) K Takashima et al.   BRITISH JOURNAL OF PHARMACOLOGY

Structure of Compositionally Simple Lipopolysaccharide from Marine Synechococcus

(2009) D. S. Snyder et al.   JOURNAL OF BACTERIOLOGY

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Roles for LPS-dependent interaction and relocation of TLR4 and TRAM in TRIF-signaling

(2008) Natsuko Tanimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TLR2 – promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity

(2008) Ulrich Zähringer et al.   IMMUNOBIOLOGY

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY