Seven New and Two Known Lipopeptides as well as Five Known Polyketides: The Activated Production of Silent Metabolites in a Marine-Derived Fungus by Chemical Mutagenesis Strategy Using Diethyl Sulphate

A Practical Strategy to Discover New Antitumor Compounds by Activating Silent Metabolite Production in Fungi by Diethyl Sulphate Mutagenesis

(2014) Shi-Ming Fang et al.   Marine Drugs

Classical and epigenetic approaches to metabolite diversification in filamentous fungi

(2013) Jacqueline Aparecida Takahashi et al.   PHYTOCHEMISTRY REVIEWS

New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters

(2012) Kozo Ochi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59

(2012) Yun-Jing Chai et al.   Marine Drugs

Purpurogemutantin and Purpurogemutantidin, New Drimenyl Cyclohexenone Derivatives Produced by a Mutant Obtained by Diethyl Sulfate Mutagenesis of a Marine-Derived Penicillium purpurogenum G59

(2012) Shi-Ming Fang et al.   Marine Drugs

Isolation, Structure, and Biological Activities of Fellutamides C and D from an UndescribedMetulocladosporiella(Chaetothyriales) Using the Genome-WideCandida albicansFitness Test

(2011) Deming Xu et al.   JOURNAL OF NATURAL PRODUCTS

Secondary metabolites of fungi from marine habitats

(2011) Mostafa E. Rateb et al.   NATURAL PRODUCT REPORTS

Fellutamide B is a potent inhibitor of the Mycobacterium tuberculosis proteasome

(2010) Gang Lin et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A Cytotoxic Lipopeptide from the Sponge-Derived Fungus Aspergillus versicolor

(2010) Yoon-Mi Lee et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Fungal secondary metabolites – Strategies to activate silent gene clusters

(2010) Axel A. Brakhage et al.   FUNGAL GENETICS AND BIOLOGY

Epigenome manipulation as a pathway to new natural product scaffolds and their congeners

(2009) Robert H. Cichewicz   NATURAL PRODUCT REPORTS

Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12

(2009) Takeshi Hosaka et al.   NATURE BIOTECHNOLOGY

Hidden biosynthetic treasures brought to light

(2009) Christian Hertweck   Nature Chemical Biology

Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis

(2008) John Hines et al.   CHEMISTRY & BIOLOGY

Advances in and applications of proteasome inhibitors

(2008) Bradley S Moore et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Structural and spectral assignments of six anthraquinone derivatives from the mangrove fungus (ZSUH-36)

(2008) Changlun Shao et al.   MAGNETIC RESONANCE IN CHEMISTRY