Discovery and Evaluation of Thiazinoquinones as Anti-Protozoal Agents

Synthesis and in vitro and in vivo evaluation of antimalarial polyamines

(2013) Lydia P.P. Liew et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimers

(2012) Stephen T. McCracken et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery and preliminary structure–activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds

(2012) Lydia P.P. Liew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Biomimetic Synthesis of Thiaplidiaquinones A and B

(2012) Iman M. Khalil et al.   JOURNAL OF NATURAL PRODUCTS

Biomimetic Synthesis of the Apoptosis-Inducing Thiazinoquinone Thiaplidiaquinone A

(2012) Anna Carbone et al.   JOURNAL OF ORGANIC CHEMISTRY

Antimalarial β-Carbolines from the New Zealand AscidianPseudodistoma opacum

(2011) Susanna T. S. Chan et al.   JOURNAL OF NATURAL PRODUCTS

Didemnidines A and B, Indole Spermidine Alkaloids from the New Zealand AscidianDidemnumsp.

(2011) Rhys Finlayson et al.   JOURNAL OF NATURAL PRODUCTS

Anti-inflammatory and Antimalarial Meroterpenoids from the New Zealand AscidianAplidium scabellum

(2011) Susanna T. S. Chan et al.   JOURNAL OF ORGANIC CHEMISTRY

How can natural products serve as a viable source of lead compounds for the development of new/novel anti-malarials?

(2011) Eric Guantai et al.   MALARIA JOURNAL

Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles

(2010) Jiayi Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules

(2010) Katharine R Watts et al.   CURRENT OPINION IN BIOTECHNOLOGY

Inhibitory Activity of Marine Sponge-Derived Natural Products against Parasitic Protozoa

(2010) Ilkay Orhan et al.   Marine Drugs

Artemisinin resistance: current status and scenarios for containment

(2010) Arjen M. Dondorp et al.   NATURE REVIEWS MICROBIOLOGY

Synthesis of structurally simplified analogues of aplidinone A, a pro-apoptotic marine thiazinoquinone

(2009) Anna Aiello et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Marine Antimalarials

(2009) Ernesto Fattorusso et al.   Marine Drugs

Synthetic medicinal chemistry of selected antimalarial natural products

(2008) Vipan Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Orthidines A–E, tubastrine, 3,4-dimethoxyphenethyl-β-guanidine, and 1,14-sperminedihomovanillamide: potential anti-inflammatory alkaloids isolated from the New Zealand ascidian Aplidium orthium that act as inhibitors of neutrophil respiratory burst

(2008) A. Norrie Pearce et al.   TETRAHEDRON