Marine Antitumor Drugs: Status, Shortfalls and Strategies

Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities

(2010) Lin Du et al.   JOURNAL OF ANTIBIOTICS

Pachycladins A−E, Prostate Cancer Invasion and Migration Inhibitory Eunicellin-Based Diterpenoids from the Red Sea Soft CoralCladiella pachyclados

(2010) Hossam M. Hassan et al.   JOURNAL OF NATURAL PRODUCTS

Fijiolides A and B, Inhibitors of TNF-α-Induced NFκB Activation, from a Marine-Derived Sediment Bacterium of the GenusNocardiopsis

(2010) Sang-Jip Nam et al.   JOURNAL OF NATURAL PRODUCTS

Anti-photoaging and Photoprotective Compounds Derived from Marine Organisms

(2010) Ramjee Pallela et al.   Marine Drugs

Marine Drugs from Sponge-Microbe Association—A Review

(2010) Tresa Remya A. Thomas et al.   Marine Drugs

Pathway-Based Identification of Biomarkers for Targeted Therapeutics: Personalized Oncology with PI3K Pathway Inhibitors

(2010) J. N. Andersen et al.   Science Translational Medicine

The odyssey of marine pharmaceuticals: a current pipeline perspective

(2010) Alejandro M.S. Mayer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Heteronemin, a spongean sesterterpene, inhibits TNFα-induced NF-κB activation through proteasome inhibition and induces apoptotic cell death

(2009) Marc Schumacher et al.   BIOCHEMICAL PHARMACOLOGY

Marine pharmacology in 2005–6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal, antituberculosis, and antiviral activities; affecting the cardiovascular, immune and nervous systems, and other miscellaneous mechanisms of action

(2009) Alejandro M.S. Mayer et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Halichondrins and E7389

(2009) Katrina L. Jackson et al.   CHEMICAL REVIEWS

Tartrolon D, a Cytotoxic Macrodiolide from the Marine-Derived ActinomyceteStreptomycessp. MDG-04-17-069

(2009) Marta Pérez et al.   JOURNAL OF NATURAL PRODUCTS

Mansouramycins A−D, Cytotoxic Isoquinolinequinones from a Marine Streptomycete(1)

(2009) Usama W. Hawas et al.   JOURNAL OF NATURAL PRODUCTS

Matrix Metalloproteinase Inhibitors (MMPIs) from Marine Natural Products: the Current Situation and Future Prospects

(2009) Chen Zhang et al.   Marine Drugs

Antitumor Compounds from Marine Actinomycetes

(2009) Carlos Olano et al.   Marine Drugs

Protein kinase Cε: an oncogene and emerging tumor biomarker

(2009) Michael A Gorin et al.   Molecular Cancer

Lodopyridone, a Structurally Unprecedented Alkaloid from a Marine Actinomycete

(2009) Katherine N. Maloney et al.   ORGANIC LETTERS

Marine natural products as inhibitors of hypoxic signaling in tumors

(2009) Dale G. Nagle et al.   PHYTOCHEMISTRY REVIEWS

Inhibition activity of sulfated polysaccharide of Sepiella maindroni ink on matrix metalloproteinase (MMP)-2

(2008) Subo Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Antitumour polyether macrolides: Four new halichondrins from the New Zealand deep-water marine sponge Lissodendoryx sp.

(2008) Sarah J.H. Hickford et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Aplidin, a Marine Organism-Derived Compound with Potent Antimyeloma Activity In vitro and In vivo

(2008) C. S. Mitsiades et al.   CANCER RESEARCH

Molecular-Targeted Antitumor Agents. 19. Furospongolide from a MarineLendenfeldiasp. Sponge Inhibits Hypoxia-Inducible Factor-1 Activation in Breast Tumor Cells

(2008) Yang Liu et al.   JOURNAL OF NATURAL PRODUCTS

Arenamides A−C, Cytotoxic NFκB Inhibitors from the Marine ActinomyceteSalinispora arenicola⊥

(2008) Ratnakar N. Asolkar et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase

(2008) T. Okouneva et al.   MOLECULAR CANCER THERAPEUTICS

Substitution on the A-Ring Confers to Bryopyran Analogues the Unique Biological Activity Characteristic of Bryostatins and Distinct From That of the Phorbol Esters

(2008) Gary E. Keck et al.   ORGANIC LETTERS

Convergent total synthesis of the racemic HIF-1 inhibitor laurenditerpenol

(2008) Michael E. Jung et al.   TETRAHEDRON LETTERS

Marine natural products as targeted modulators of the transcription factor NF-κB

(2007) Florence Folmer et al.   BIOCHEMICAL PHARMACOLOGY

Metalloproteinases and their inhibitors: Regulators of wound healing

(2007) S GILL et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY