Cyclodepsipeptides from Marine Sponges: Natural Agents for Drug Research

Therapeutic strategies underpinning the development of novel techniques for the treatment of HIV infection

(2010) Jian J. Tan et al.   DRUG DISCOVERY TODAY

Aplidin as a potential adjunct to radiation therapy: In vitro studies

(2010) Sara Rockwell et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Non-methylene-interrupted fatty acids from marine invertebrates: Occurrence, characterization and biological properties

(2009) Gilles Barnathan   BIOCHIMIE

Pak protein kinases and their role in cancer

(2009) Bettina Dummler et al.   CANCER AND METASTASIS REVIEWS

Antimalarial natural products of marine and freshwater origin

(2009) Karl Gademann et al.   CHEMICAL RECORD

Cancer Treatments: Can We Find Treasures at the Bottom of the Sea?

(2009) Mariano Provencio et al.   Clinical Lung Cancer

Marine Sponges: Potential Sources of New Antimicrobial Drugs

(2009) M. Laport et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Phase II study of weekly Kahalalide F in patients with advanced malignant melanoma

(2009) Salvador Martín-Algarra et al.   EUROPEAN JOURNAL OF CANCER

Phase II Study of Biweekly Plitidepsin as Second-Line Therapy for Advanced or Metastatic Transitional Cell Carcinoma of the Urothelium

(2009) Herlinde Dumez et al.   Marine Drugs

Synthesis and stereochemical determination of the spirastrellolides

(2009) Ian Paterson et al.   NATURAL PRODUCT REPORTS

Homophymines B–E and A1–E1, a family of bioactive cyclodepsipeptides from the sponge Homophymia sp.

(2009) Angela Zampella et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Initial testing of aplidin by the pediatric pre-clinical testing program

(2009) Christopher L. Morton et al.   PEDIATRIC BLOOD & CANCER

Invariant natural killer T cells: innate-like T cells with potent immunomodulatory activities

(2009) L. Wu et al.   TISSUE ANTIGENS

Total Synthesis and Structure Assignment of Papuamide B, A Potent Marine Cyclodepsipeptide with Anti-HIV Properties

(2008) Weiqing Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide

(2008) Stefania Terracciano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Population pharmacokinetics meta-analysis of plitidepsin (Aplidin®) in cancer subjects

(2008) Ricardo Nalda-Molina et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Aplidin, a Marine Organism-Derived Compound with Potent Antimyeloma Activity In vitro and In vivo

(2008) C. S. Mitsiades et al.   CANCER RESEARCH

Phase I Clinical and Pharmacokinetic Study of Plitidepsin as a 1-Hour Weekly Intravenous Infusion in Patients with Advanced Solid Tumors

(2008) M. A. Izquierdo et al.   CLINICAL CANCER RESEARCH

Phase I Clinical and Pharmacokinetic Study of Kahalalide F Administered Weekly as a 1-Hour Infusion to Patients with Advanced Solid Tumors

(2008) B. Pardo et al.   CLINICAL CANCER RESEARCH

Synthetic Glycolipid Ligands for Human iNKT Cells as Potential Therapeutic Agents for Immunotherapy

(2008) Manabu Araki et al.   CURRENT MEDICINAL CHEMISTRY

Role of Invariant Natural Killer T (iNKT) Cells in Systemic Lupus Erythematosus

(2008) Maria Godo et al.   CURRENT MEDICINAL CHEMISTRY

The geodiamolide H, derived from brazilian spongeGeodia corticostylifera, regulates actin cytoskeleton, migration and invasion of breast cancer cells cultured in three‐dimensional environment

(2008) Vanessa M. Freitas et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Homophymine A, an Anti-HIV Cyclodepsipeptide from the SpongeHomophymiasp.

(2008) Angela Zampella et al.   JOURNAL OF ORGANIC CHEMISTRY

Celebesides A−C and Theopapuamides B−D, Depsipeptides from an Indonesian Sponge That Inhibit HIV-1 Entry

(2008) Alberto Plaza et al.   JOURNAL OF ORGANIC CHEMISTRY

Characterizing the Anti-HIV Activity of Papuamide A

(2008) Cynthia Andjelic et al.   Marine Drugs

Depsipeptides from Microorganisms: A New Class of Antimalarials

(2008) Jean Fotie et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Tedanolide and the evolution of polyketide inhibitors of eukaryotic protein synthesis

(2008) Richard E. Taylor   NATURAL PRODUCT REPORTS

Marine natural products

(2008) John W. Blunt et al.   NATURAL PRODUCT REPORTS

Deep-sea natural products

(2008) Danielle Skropeta   NATURAL PRODUCT REPORTS

Phase II study of plitidepsin in pretreated patients with locally advanced or metastatic non-small cell lung cancer

(2007) Christian Peschel et al.   LUNG CANCER