The plant-based immunomodulator curcumin as a potential candidate for the development of an adjunctive therapy for cerebral malaria

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies

(2010) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Facile Oxidation of Leucomethylene Blue and Dihydroflavins by Artemisinins: Relationship with Flavoenzyme Function and Antimalarial Mechanism of Action

(2010) Richard K. Haynes et al.   ChemMedChem

Modulation of cerebral malaria by fasudil and other immune-modifying compounds

(2010) Judith H. Waknine-Grinberg et al.   EXPERIMENTAL PARASITOLOGY

Novel formulation of solid lipid microparticles of curcumin for anti-angiogenic and anti-inflammatory activity for optimization of therapy of inflammatory bowel disease

(2010) Vivek Ramshankar Yadav et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

(2010) Arjen M Dondorp et al.   LANCET

Artemisinin Directly Targets Malarial Mitochondria through Its Specific Mitochondrial Activation

(2010) Juan Wang et al.   PLoS One

Genome Wide Analysis of Inbred Mouse Lines Identifies a Locus Containing Ppar-γ as Contributing to Enhanced Malaria Survival

(2010) Selina E. R. Bopp et al.   PLoS One

Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate

(2010) J. Brian de Souza et al.   PLoS One

Inhibition of Plasmodium falciparum Field Isolates-Mediated Endothelial Cell Apoptosis by Fasudil: Therapeutic Implications for Severe Malaria

(2010) Estelle S. Zang-Edou et al.   PLoS One

Neuropathogenesis of human and murine malaria

(2010) Eleanor M. Riley et al.   TRENDS IN PARASITOLOGY

Cognitive Dysfunction Is Sustained after Rescue Therapy in Experimental Cerebral Malaria, and Is Reduced by Additive Antioxidant Therapy

(2010) Patricia A. Reis et al.   PLoS Pathogens

Curcumin enhances non-inflammatory phagocytic activity of RAW264.7 cells

(2009) Kavita Bisht et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism

(2009) Hong-Fang Ji et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Plasmodium falciparum-infected erythrocytes induce NF- B regulated inflammatory pathways in human cerebral endothelium

(2009) A. K. Tripathi et al.   BLOOD

Use of Peroxisome Proliferator‐Activated Receptor γ Agonists as Adjunctive Treatment forPlasmodium falciparumMalaria: A Randomized, Double‐Blind, Placebo‐Controlled Trial

(2009) Andrea K. Boggild et al.   CLINICAL INFECTIOUS DISEASES

N-acetylcysteine as adjunctive treatment in severe malaria: A randomized, double-blinded placebo-controlled clinical trial*

(2009) Prakaykaew Charunwatthana et al.   CRITICAL CARE MEDICINE

Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications

(2009) J. Alexandra Rowe et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Evaluation of an Oral Carrier System in Rats: Bioavailability and Antioxidant Properties of Liposome-Encapsulated Curcumin

(2009) Makoto Takahashi et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Rosiglitazone Modulates the Innate Immune Response toPlasmodium falciparumInfection and Improves Outcome in Experimental Cerebral Malaria

(2009) Lena Serghides et al.   JOURNAL OF INFECTIOUS DISEASES

Anti-malarial activities of Andrographis paniculata and Hedyotis corymbosa extracts and their combination with curcumin

(2009) Kirti Mishra et al.   MALARIA JOURNAL

Safety of epoietin beta-quinine drug combination in children with cerebral malaria in Mali

(2009) Stéphane Picot et al.   MALARIA JOURNAL

Disruption of Nrf2 Enhances Upregulation of Nuclear Factor-κB Activity, Proinflammatory Cytokines, and Intercellular Adhesion Molecule-1 in the Brain after Traumatic Brain Injury

(2009) Wei Jin et al.   MEDIATORS OF INFLAMMATION

Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment

(2009) Katie R. Hughes et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Embryotoxicity of the artemisinin antimalarials and potential consequences for use in women in the first trimester

(2009) Robert L. Clark   REPRODUCTIVE TOXICOLOGY

Platelets Kill Intraerythrocytic Malarial Parasites and Mediate Survival to Infection

(2009) B. J. McMorran et al.   SCIENCE

The murine cerebral malaria phenomenon

(2009) Nicholas J. White et al.   TRENDS IN PARASITOLOGY

Effect of curcumin on the adhesion of platelets to brain microvascular endothelial cellsin vitro1

(2008) Li ZHANG et al.   ACTA PHARMACOLOGICA SINICA

Artesunate–erythropoietin combination for murine cerebral malaria treatment

(2008) Anne-Lise Bienvenu et al.   ACTA TROPICA

Synthesis and exploration of novel curcumin analogues as anti-malarial agents

(2008) Satyendra Mishra et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Plasmodium chabaudi: Efficacy of artemisinin+curcumin combination treatment on a clone selected for artemisinin resistance in mice

(2008) Axel Martinelli et al.   EXPERIMENTAL PARASITOLOGY

Oxidised LDL up-regulate CD36 expression by the Nrf2 pathway in 3T3-L1 preadipocytes

(2008) Massimo D'Archivio et al.   FEBS LETTERS

Immunomodulatory effects of curcumin: In-vivo

(2008) Ch. Varalakshmi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Rho Kinase Inhibition in Severe Malaria: Thwarting Parasite‐Induced Collateral Damage to Endothelia

(2008) Zacharie Taoufiq et al.   JOURNAL OF INFECTIOUS DISEASES

Curcumin and the cellular stress response in free radical-related diseases

(2008) Vittorio Calabrese et al.   MOLECULAR NUTRITION & FOOD RESEARCH

High levels of erythropoietin are associated with protection against neurological sequelae in African children with cerebral malaria

(2008) C. Casals-Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical significance of sequestration in adults with severe malaria

(2008) A.M. Dondorp   TRANSFUSION CLINIQUE ET BIOLOGIQUE

Can erythropoietin be used to prevent brain damage in cerebral malaria?

(2008) Climent Casals-Pascual et al.   TRENDS IN PARASITOLOGY

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

(2008) Bharat B. Aggarwal et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Curcumin as “Curecumin”: From kitchen to clinic

(2007) Ajay Goel et al.   BIOCHEMICAL PHARMACOLOGY