Natural products as starting points for future anti-malarial therapies: going back to our roots?

Xenobiotic Metabolism: A View through the Metabolometer

(2010) Andrew D. Patterson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Ethnopharmacology, sustainable development and cooperation: The importance of gathering clinical data during field surveys

(2010) B. Graz et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antimalarial activity and toxicity evaluation of a quantified Nauclea pobeguinii extract

(2010) Kahunu Mesia et al.   JOURNAL OF ETHNOPHARMACOLOGY

New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays

(2010) Jonathan B. Baell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antimalarial compounds isolated from plants used in traditional medicine

(2010) Joanne Bero et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Flavonoids from Artemisia annua L. as Antioxidants and Their Potential Synergism with Artemisinin against Malaria and Cancer

(2010) Jorge F.S. Ferreira et al.   MOLECULES

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Is the Tide Turning for New Malaria Medicines?

(2010) T. N. C. Wells   SCIENCE

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination

(2010) Timothy N.C. Wells et al.   TRENDS IN PARASITOLOGY

Improved Murine Model of Malaria Using Plasmodium falciparum Competent Strains and Non-Myelodepleted NOD-scid IL2R null Mice Engrafted with Human Erythrocytes

(2009) M. B. Jimenez-Diaz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and biological evaluation of febrifugine analogues as potential antimalarial agents

(2009) Shuren Zhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Clinical Trial of the Traditional Medicine Vernonia amygdalina in the Treatment of Uncomplicated Malaria

(2009) Simon Challand et al.   JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE

The African Network for Drugs and Diagnostics Innovation

(2009) Tom Mboya-Okeyo et al.   LANCET

Hyperparasitaemia and low dosing are an important source of anti-malarial drug resistance

(2009) Nicholas J White et al.   MALARIA JOURNAL

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Argemone mexicana decoction versus artesunate-amodiaquine for the management of malaria in Mali: policy and public-health implications

(2009) Bertrand Graz et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Late Onset of Bladder Urothelial Carcinoma After Kidney Transplantation for End-Stage Aristolochic Acid Nephropathy: A Case Series With 15-Year Follow-up

(2008) Anne Lemy et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Ligand Binding Efficiency: Trends, Physical Basis, and Implications

(2008) Charles H. Reynolds et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina

(2008) Anoka A. Njan et al.   JOURNAL OF MEDICINAL FOOD

Genomic-scale prioritization of drug targets: the TDR Targets database

(2008) Fernán Agüero et al.   NATURE REVIEWS DRUG DISCOVERY

Drug development from marine natural products

(2008) Tadeusz F. Molinski et al.   NATURE REVIEWS DRUG DISCOVERY

Analysis of the adult human plasma metabolome

(2008) Kay A Lawton et al.   PHARMACOGENOMICS

In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

(2008) David Plouffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herba Artemisiae annuae tea preparation compared to sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria in adults: a randomized double-blind clinical trial

(2008) Christoph H Blanke et al.   TROPICAL DOCTOR