Article
Radiology, Nuclear Medicine & Medical Imaging
Yannik Leonhardt, Florian T. Gassert, Georg Feuerriegel, Felix G. Gassert, Sophia Kronthaler, Christof Boehm, Alexander Kufner, Stefan Ruschke, Thomas Baum, Benedikt J. Schwaiger, Marcus R. Makowski, Dimitrios C. Karampinos, Alexandra S. Gersing
Summary: Chemical shift encoding-based water-fat separation techniques can be used for fat quantification and bone marrow T2* assessment. This study found significant correlations between T2*, bone mineral density, trabecular number, and trabecular spacing. T2* mapping allows for differentiation between low-energy osteoporotic and high-energy traumatic vertebral fractures, suggesting its potential as a biomarker for bone fragility.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Quantum Science & Technology
Carla Silva, Ana Aguiar, Priscila M. Lima, Ines Dutra
Summary: This study presents the mapping of the TSP problem to a graph of D-Wave Systems Inc., converting constraints to energy minimization and solving using classical QUBO, simulated quantum environment, and D-Wave quantum machine. Results show D-Wave machine finds optimal solutions more often, but with higher execution times for small graphs, while the quantum machine outperforms classical for a higher number of nodes.
QUANTUM INFORMATION PROCESSING
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Pierre Daude, Tangi Roussel, Thomas Troalen, Patrick Viout, Diego Hernando, Maxime Guye, Frank Kober, Sylviane Confort Gouny, Monique Bernard, Stanislas Rapacchi
Summary: This study proposes a standardized comparison method for open-source fat-water separation algorithms in proton density fat fraction (PDFF) and R2* quantification. Eight algorithms were compared in simulation, in vitro, and in vivo experiments, revealing discrepancies between the approaches. The results show that four algorithms have reliable performance, but the choice of fat spectrum model has a significant impact on R2* quantification.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Beata Bachrata, Siegfried Trattnig, Simon Daniel Robinson
Summary: The SMURF technique successfully generated separate fat and water images of the head-and-neck, allowing for accurate susceptibility mapping after corrections for chemical shift artifacts and relaxation rate differences. The proposed masking method proved to be a simple and effective way to generate head-and-neck masks.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Umi Nabilah Ismail, Che Ahmad Azlan, Shasha Khairullah, Raja Rizal Azman, Kuan Jin Lee, Chai Hong Yeong, Nur Farhayu Omar, Norlisah Ramli, Mohammad Nazri Md Shah, Nicholas Jackson, Kwan Hoong Ng
Summary: This study used chemical shift-encoded (CSE)-MRI to investigate the changes in bone marrow fat in patients affected by beta-thalassemia and found that it was correlated with disease severity. CSE-MRI is a promising tool for quantitatively evaluating changes and variability in marrow fat distribution.
ACADEMIC RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hao Peng, Chuanli Cheng, Qian Wan, Dong Liang, Xin Liu, Hairong Zheng, Chao Zou
Summary: To reduce the ambiguity between chemical shift and field inhomogeneity, a variable (field factor) was introduced to flexibly select TE combinations. The ambiguity problem was reduced by eliminating the effects of chemical shift on the field inhomogeneity in the candidate solutions. The proposed algorithm achieved robust fat-water separation in various applications.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Houchun H. Hu, Takeshi Yokoo, Mustafa R. Bashir, Claude B. Sirlin, Diego Hernando, Dariya Malyarenko, Thomas L. Chenevert, Mark A. Smith, Suraj D. Serai, Michael S. Middleton, Walter C. Henderson, Gavin Hamilton, Jean Shaffer, Yunhong Shu, Jean A. Tkach, Andrew T. Trout, Nancy Obuchowski, Jean H. Brittain, Edward F. Jackson, Scott B. Reeder
Summary: This study aimed to evaluate the accuracy of CSE MRI methods for estimating PDFF, showing high correlation within the biologically relevant PDFF range. The slopes and intercepts across vendors and field strengths were within acceptable ranges, indicating that PDFF estimation using CSE MRI is accurate in different settings.
Article
Radiology, Nuclear Medicine & Medical Imaging
Nathan T. Roberts, Diego Hernando, Nikolaos Panagiotopoulos, Scott B. Reeder
Summary: This study proposes a complex-based fitting method that addresses concomitant gradient phase errors in chemical shift encoded MRI estimation. The method allows accurate quantification of proton density fat fraction and R-2* without prior knowledge of imaging gradient waveforms. The proposed method was validated in phantom and in vivo experiments, showing significant improvement in estimation accuracy.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jannis Hanspach, Steffen Bollmann, Johanna Grigo, Andre Karius, Michael Uder, Frederik B. Laun
Summary: This study proposes a deep learning-based approach for fast and automatic QSM reconstruction of tissues with diverse chemical shifts. The approach, trained solely with synthetic data, can rapidly reconstruct high-quality susceptibility maps without the need for background masking.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sara Berardo, Lidiia Sukhovei, Silvano Andorno, Alessandro Carriero, Alessandro Stecco
Summary: Objective quantitative MR sequences such as DWI and CSI were used to evaluate the water-fat composition of bone marrow in MM patients. The study found that ADC and FF could be potentially useful parameters for assessing BM infiltration in MM patients, aiding in diagnosis and classification.
Article
Biology
Zeyuan Chen, Xiulan Zhai, Zikuan Chen
Summary: In this paper, we address the issue of dealing with the oblique effect in quantitative susceptibility mapping (QSM) when using phase image matrix acquired from oblique MRI. We propose a method called tiltQSM, which involves matrix rotation of the phase image and dipole kernel in a preprocessing subroutine prior to regular QSM reconstruction. The results show that tiltQSM can achieve good performance for small tilting angles (<10°).
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Henric Ryden, Ola Norbeck, Enrico Avventi, Mikael Skorpil, Adam van Niekerk, Stefan Skare, Johan Berglund
Summary: The use of asymmetric readout waveforms for chemical shift encoding offers a more efficient way to achieve fat/water imaging with improved SNR. By shortening scan times and maintaining or increasing SNR levels, this method provides flexibility in pulse sequence designs.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Myles T. Taffel, Robert D. Petrocelli, Danielle Rigau, Nicola Schieda, Sumaya Al-Rasheed, Benjamin W. Carney, Ryan Chung, Michael L. Yao, Michael A. Blake, Khaled M. Elsayes, Mohamed Badawy, Sergio Klimkowski, Erick M. Remer, Adam Wetzel, Amit Pandya, Elaine M. Caoili, Michael T. Corwin
Summary: The presence of heterogeneous microscopic fat in adrenal nodules on chemical-shift MRI indicates a high likelihood of benignancy, particularly in patients without prior cancer. Additional imaging evaluation is not required for adrenal nodules with heterogeneous microscopic fat in the absence of prior cancer.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christof Boehm, Maximilian N. Diefenbach, Marcus R. Makowski, Dimitrios C. Karampinos
Summary: A robust algorithm for field-mapping in the presence of water-fat components, large B0 field inhomogeneities and MR signal voids was developed and applied in body applications of quantitative susceptibility mapping, showing accurate results especially in regions with low SNR, strong field-map variations and high R2* values. The new method outperformed the iterative graph-cut algorithm in improving quantitative susceptibility mapping close to MR signal voids.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Medicine, General & Internal
Sarah Schlaeger, Nico Sollmann, Agnes Zoffl, Edoardo Aitala Becherucci, Dominik Weidlich, Elisabeth Kottmaier, Isabelle Riederer, Tobias Greve, Federica Montagnese, Marcus Deschauer, Benedikt Schoser, Claus Zimmer, Dimitrios C. Karampinos, Jan S. Kirschke, Thomas Baum
Summary: The study aimed to assess the diagnostic value of PDFF in correlation to Mercuri grading and clinically determined muscle strength in patients with DM2, LGMD2A, and Pompe disease. The results showed a strong correlation between Mercuri grading and PDFF values for almost all muscles, and significant correlations between PDFF values and muscle strength for muscle groups responsible for knee flexion. This suggests that PDFF could be further considered as an MRI-based biomarker in the assessment of fatty infiltration of muscle tissue in NMD, with advantages such as greater dynamic range, amplified objectivity, and potential direct correlation to muscle function.
Article
Radiology, Nuclear Medicine & Medical Imaging
Anna Gardin, Pawel Rasinski, Johan Berglund, Adel Shalabi, Helene Schulte, Torkel B. Brismar
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2016)
Article
Radiology, Nuclear Medicine & Medical Imaging
Johan Berglund, Mikael Skorpil
MAGNETIC RESONANCE IN MEDICINE
(2017)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mikael Skorpil, Henric Ryden, Johan Wejde, Elisabet Lidbrink, Otte Brosjo, Johan Berglund
MAGNETIC RESONANCE IMAGING
(2017)
Article
Radiology, Nuclear Medicine & Medical Imaging
Henric Ryden, Johan Berglund, Ola Norbeck, Enrico Avventi, Stefan Skare
MAGNETIC RESONANCE IN MEDICINE
(2018)
Article
Radiology, Nuclear Medicine & Medical Imaging
M. Skorpil, H. Ryden, J. Berglund, P. Brynolfsson, O. Brosjo, P. Tsagozis
CLINICAL RADIOLOGY
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Johan Berglund, Henric Ryden, Enrico Avventi, Ola Norbeck, Tim Sprenger, Stefan Skare
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ola Norbeck, Tim Sprenger, Enrico Avventi, Henric Ryden, Annika Kits, Johan Berglund, Stefan Skare
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Henric Ryden, Johan Berglund, Ola Norbeck, Enrico Avventi, Tim Sprenger, Adam van Niekerk, Stefan Skare
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Enrico Avventi, Henric Ryden, Ola Norbeck, Johan Berglund, Tim Sprenger, Stefan Skare
MAGNETIC RESONANCE IN MEDICINE
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Johan Berglund, Adam van Niekerk, Henric Ryden, Tim Sprenger, Enrico Avventi, Ola Norbeck, Stefan L. Glimberg, Oline V. Olesen, Stefan Skare
Summary: This study utilized an optical markerless tracking system for real-time rigid body motion correction during scanning, enabling motion-robust diffusion weighted imaging of the brain. Prospective motion correction with dynamic ghost correction allowed for high quality DWI images in the presence of fast and continuous motion within a 10 degrees range.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ola Norbeck, Adam van Niekerk, Enrico Avventi, Henric Ryden, Johan Berglund, Tim Sprenger, Stefan Skare
Summary: This study introduces a T-1-weighted FLAIR sequence that actively corrects motion during acquisition, using an intelligent marker for navigation positioning. By combining two motion correction methods, the sequence is able to produce sharp MRI images even during large continuous motion.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Henric Ryden, Ola Norbeck, Enrico Avventi, Mikael Skorpil, Adam van Niekerk, Stefan Skare, Johan Berglund
Summary: The use of asymmetric readout waveforms for chemical shift encoding offers a more efficient way to achieve fat/water imaging with improved SNR. By shortening scan times and maintaining or increasing SNR levels, this method provides flexibility in pulse sequence designs.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Adam van Niekerk, Johan Berglund, Tim Sprenger, Ola Norbeck, Enrico Avventi, Henric Ryden, Stefan Skare
Summary: This study successfully synchronized information between a wireless motion-tracking device and a pulse sequence, demonstrating customizable navigator interleaving schemes. By utilizing RF signatures, complex interactions were enabled, leading to successful motion correction in MRI scanners without hardware modifications.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Johan Berglund, Tim Sprenger, Adam van Niekerk, Henric Ryden, Enrico Avventi, Ola Norbeck, Stefan Skare
Summary: This study explores the application of prospective and retrospective motion correction in interleaved snapshot EPI for susceptibility-weighted imaging (SWI), showing its superiority in mitigating the interference of head movement and maintaining stable image quality. Compared to traditional methods, interleaved snapshot EPI demonstrates better performance, particularly suitable for patients who are prone to movement.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Tim Sprenger, Annika Kits, Ola Norbeck, Adam van Niekerk, Johan Berglund, Henric Ryden, Enrico Avventi, Stefan Skare
Summary: NeuroMix is a customizable and fast brain MRI scanning method that can complete a full brain scan in 1:20 to 4 minutes. Compared to its predecessor EPIMix, NeuroMix showed significant improvements in T2-weighted and T2 FLAIR sequences, while only taking an additional 8 seconds for a similar configuration. Optional imaging contrasts were less motion robust but provided a significant increase in quality, detail, and contrast.
MAGNETIC RESONANCE IN MEDICINE
(2022)