Journal
MAGNETIC RESONANCE IN CHEMISTRY
Volume 53, Issue 2, Pages 115-119Publisher
WILEY
DOI: 10.1002/mrc.4149
Keywords
NMR; HSQC; pure in-phase signals; perfect HSQC; J(HH) modulation
Funding
- Ministerio de Economia y Competitividad [CTQ2012-32436]
Ask authors/readers for more resources
The amplitude and the phase of cross peaks in conventional 2D HSQC experiments are modulated by both proton-proton, J(HH), and proton-carbon, (1)J(CH), coupling constants. It is shown by spectral simulation and experimentally that J(HH) interferences are suppressed in a novel perfect-HSQC pulse scheme that incorporates perfect-echo INEPT periods. The improved 2D spectra afford pure in-phase cross peaks with respect to (1)J(CH) and J(HH), irrespective of the experiment delay optimization. In addition, peak volumes are not attenuated by the influence of J(HH), rendering practical issues such as phase correction, multiplet analysis, and signal integration more appropriate. Copyright (c) 2014 John Wiley & Sons, Ltd.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available