Article
Medicine, General & Internal
Zhi-bo Hou, Fei Zhao, Bin Zhang, Chun-zhu Zhang
Summary: The study found that SWI combined with DWI scanning has a higher coincidence rate in diagnosing small hepatocellular carcinoma in patients with liver cirrhosis compared to conventional MRI scanning, with significant advantages in terms of specificity, sensitivity, and accuracy.
PAKISTAN JOURNAL OF MEDICAL SCIENCES
(2021)
Article
Oncology
Alexey Surov, Maciej Pech, Jazan Omari, Frank Fischbach, Robert Damm, Katharina Fischbach, Maciej Powerski, Borna Relja, Andreas Wienke
Summary: The study found that minimum ADC reflects tumor grading in HCC, while both minimum ADC and D can predict MVI in HCC. Therefore, these DWI parameters should be estimated for pretreatment tumor stratification in each HCC lesion.
Article
Oncology
Jin Gu, Erlei Zhang, Binyong Liang, Zunyi Zhang, Xiaoping Chen, Min Xiong, Zhiyong Huang
Summary: In HCC patients with Child-Pugh grade A liver function, cirrhosis staging can be determined by measuring liver collagen contents using Collagen Proportional Area (CPA), which significantly affects the risk of Posthepatectomy Liver Failure (PHLF). The study also found a significant correlation between CPA and a non-invasive method called Cirrhotic Severity Scoring (CSS) proposed by the team, showing that higher CPA values and extent of hepatectomy are independent risk factors for PHLF, and there is a positive correlation between CPA and CSS.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marc Saake, Hannes Seuss, Andreas Riexinger, Sebastian Bickelhaupt, Matthias Hammon, Michael Uder, Frederik B. Laun
Summary: This study compared the effectiveness of diffusion-weighted imaging obtained with free breathing and navigator triggering in noncirrhotic patients. The results showed that navigator triggering was better for detecting small FLLs, while both free breathing and navigator triggering were similarly good for detecting large FLLs.
INVESTIGATIVE RADIOLOGY
(2021)
Article
Oncology
Koya Yasukawa, Akira Shimizu, Koji Kubota, Tsuyoshi Notake, Kiyotaka Hosoda, Hikaru Hayashi, Yuji Soejima
Summary: This study aimed to investigate the impact of liver fibrosis on the prognosis of patients with hepatocellular carcinoma (HCC). The results showed that patients with more severe liver fibrosis had worse cancer-specific prognosis. Moreover, patients with liver fibrosis had a higher incidence of multiple recurrences.
Article
Radiology, Nuclear Medicine & Medical Imaging
Tetsuro Kaga, Yoshifumi Noda, Masashi Asano, Nobuyuki Kawai, Kimihiro Kajita, Fuminori Hyodo, Hiroki Kato, Masayuki Matsuo
Summary: This study assessed the diagnostic abilities of DWI with PI-DWI and EPICS-DWI for differentiating HHs and LMs. The results showed that EPICS-DWI had better conspicuity and CNR for LMs compared to PI-DWI. However, the cutoff ADC values and diagnostic abilities for differentiating HHs and LMs were almost comparable between the two sequences.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Qian Li, Tong Zhang, Feng Che, Shan Yao, Feifei Gao, Lisha Nie, Hehan Tang, Yi Wei, Bin Song
Summary: Intravoxel incoherent motion (IVIM) parameters, especially D and D* values, may serve as reliable preoperative predictors of liver regeneration.
EUROPEAN RADIOLOGY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Giuseppe Mamone, Settimo Caruso, Mariapina Milazzo, Giorgia Porrello, Ambra Di Piazza, Giovanni Gentile, Vincenzo Carollo, Francesca Crino, Gianluca Marrone, Gianvincenzo Sparacia, Luigi Maruzzelli, Roberto Miraglia, Salvatore Gruttadauria
Summary: Liver transplantation provides the best survival benefit for hepatocellular carcinoma (HCC) patients who cannot undergo resection. The Milan criteria have been developed to select suitable candidates for transplantation, aiming to improve survival and reduce the risk of HCC recurrence. However, up to 20% of cases experience HCC recurrence after transplantation, posing a significant challenge due to poor prognosis. Various extended criteria have been proposed to accommodate the increasing demand for organs and the associated higher risk of recurrence. Radiologists need to be aware of the possibility of HCC recurrence involving multiple organs after transplantation. Understanding the location and radiologic appearance of recurrent HCC is crucial for choosing the most appropriate therapy.
INSIGHTS INTO IMAGING
(2023)
Article
Multidisciplinary Sciences
Shaiju S. Nazeer, Ariya Saraswathy, Nirmala Nimi, Hema Santhakumar, Parvathy Radhakrishnapillai Suma, Sachin J. Shenoy, Ramapurath S. Jayasree
Summary: To address the toxicity issues of traditional nanomaterials in the biological field, smart nanomaterials (SNs) with controlled features have been synthesized. In this study, theranostic SNs based on iron oxide were developed for simultaneous magnetic hyperthermia and MRI. The prepared ASPIONs showed efficient MRI contrast and potential for hyperthermia-based therapeutic approach. The magnetic and imaging capabilities of ASPIONs were evaluated in vitro and in vivo, and the liver targeting efficacy and short-term safety were confirmed.
SCIENTIFIC REPORTS
(2023)
Review
Medicine, General & Internal
Tin Nadarevic, Agostino Colli, Vanja Giljaca, Mirella Fraquelli, Giovanni Casazza, Cristina Manzotti, Davor Stimac, Damir Miletic
Summary: Hepatocellular carcinoma, a common cancer in patients with chronic liver disease, presents challenges in diagnosis. This study evaluated the diagnostic accuracy of MRI in hepatocellular carcinoma. The findings reveal that using MRI as a second-line imaging modality to diagnose hepatocellular carcinoma of any size and stage may result in missed diagnoses in 16% of patients, while 6% of non-hepatocellular carcinoma patients may be unnecessarily treated. For resectable hepatocellular carcinoma, 16% of patients may not receive appropriate surgery, and 7% of non-hepatocellular carcinoma patients may undergo unnecessary surgery. However, due to high risk of bias in the included studies and concerns regarding applicability, confidence-level conclusions cannot be drawn based on these results.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ji Young Choi, Sang Hyun Choi, Jae Ho Byun, So Jung Lee, So Yeon Kim, Hyung Jin Won, Yong Moon Shin
Summary: The purpose of this study was to evaluate and compare the diagnostic performance of Liver Imaging Reporting and Data System (LI-RADS) v2018 for hepatocellular carcinoma (HCC) <= 3.0 cm on gadoxetic acid-enhanced MRI according to the etiology of cirrhosis. The sensitivity of LI-RADS for diagnosing HCC <= 3.0 cm was significantly lower in the alcoholic liver cirrhosis (ALC) group than in the hepatitis B virus-related cirrhosis (HBV) group.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Guillermo Carbonell, Paul Kennedy, Octavia Bane, Ammar Kirmani, Maria El Homsi, Daniel Stocker, Daniela Said, Pritam Mukherjee, Olivier Gevaert, Sara Lewis, Stefanie Hectors, Bachir Taouli
Summary: The precision of MRI radiomics features in HCC tumors and liver parenchyma shows moderate to excellent test-retest repeatability within the same MRI system. However, there is poor inter-platform reproducibility across different MRI systems, except for shape and 1st-order features on T1WI. Inter-observer reproducibility is good to excellent in HCCs but moderate to good in liver tissue.
EUROPEAN RADIOLOGY
(2022)
Article
Nutrition & Dietetics
Xuan-vinh Kevin Nguyen, Jason Zhang, Ken Lee Chin, Stephen Bloom, Amanda J. Nicoll
Summary: This study compared the characteristics and survival rates of NAFLD-HCC patients to non-NAFLD-HCC patients, finding that NAFLD-HCC patients were more likely to be diagnosed based on symptoms and at an older age, with lower survival rates.
Review
Oncology
Fei Wang, Chun Yue Yan, Cai Hong Wang, Yan Yang, Dong Zhang
Summary: In this study, the predictive power of diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM)-diffusion-weighted imaging (DWI) parameters for pathological grades and microvascular invasion (MVI) in hepatocellular carcinoma (HCC) was investigated and compared. The results showed that certain parameters had high sensitivity and specificity in the preoperative prediction of HCC pathological grades and MVI. Additionally, MD and D values had superior diagnostic efficacy in predicting HCC grades, while D value outperformed other parameters in predicting MVI+ in HCC.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hai-Feng Liu, Yong-Sheng Xu, Zhao Liu, Kuan-Yu Che, Ye Sheng, Jiu-Le Ding, Jing-Gang Zhang, Jun-Qiang Lei, Wei Xing
Summary: The study found that Gd-EOB-DTPA enhanced MRI is superior to DWI in diagnosing residual HCCs after DEB-TACE. Arterial hypervascularity and DWI hyperintensity are important imaging features in distinguishing residual HCCs from necrotic tumors.
ACADEMIC RADIOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
F. Le Moigne, T. Vitry, P. Gerome, N. Vinurel, C. Ducerf, A. Rode, B. Bancel
DIAGNOSTIC AND INTERVENTIONAL IMAGING
(2016)
Editorial Material
Medicine, General & Internal
C. de Charry, O. Bylicki, E. Mavrovi, F. Le Moigne, F. de Charry
REVUE DE MEDECINE INTERNE
(2018)
Article
Pediatrics
A. Drouet, F. Le Moigne, D. Salame, L. Quesnel, C. Motolese, V. des Portes, L. Guilloton, S. Pinson
ARCHIVES DE PEDIATRIE
(2014)
Editorial Material
Cardiac & Cardiovascular Systems
Francois Le Moigne, Jean-Laurent Lamboley, Thierry Vitry, Vincent Griffet
ARCHIVES OF CARDIOVASCULAR DISEASES
(2013)
Article
Radiology, Nuclear Medicine & Medical Imaging
F. Le Moigne, L. Boussel, A. Haquin, B. Bancel, C. Ducerf, Y. Berthezene, A. Rode
BRITISH JOURNAL OF RADIOLOGY
(2014)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
C. de Charry, F. de Charry, J. -L. Lamboley, F. Le Moigne, L. Guilloton
FEUILLETS DE RADIOLOGIE
(2012)
Article
Urology & Nephrology
Charlotte de Charry, Felicite de Charry, Francois Lemoigne, Jean-Laurent Lamboley, Florian Pasquet, Michel Pavic
NEPHROLOGIE & THERAPEUTIQUE
(2012)
Editorial Material
Medicine, General & Internal
C. de Charry, F. de Charry, F. Le Moigne, J. -L. Lamboley, T. Vitry, P. Michel
REVUE DE MEDECINE INTERNE
(2013)
Letter
Clinical Neurology
O. Bruneau, F. Le Moigne, J. Guyotat, E. Nicolas-Virelizier, L. Guilloton, A. Drouet
REVUE NEUROLOGIQUE
(2013)
Editorial Material
Rheumatology
Cyrielle Genicon, Laurent Guilloton, Michel Pavic, Francois Le Moigne
Editorial Material
Rheumatology
Cyrielle Genicon, Francois Le Moigne
Editorial Material
Rheumatology
Cyrielle Genicon, Frederic Rongieras, Francois Le Moigne
Article
Radiology, Nuclear Medicine & Medical Imaging
Clement Devic, Larry Bodgi, Laurene Sonzogni, Frank Pilleul, Herve Ribot, Charlotte De Charry, Francois Le Moigne, Didier Paul, Fanny Carbillet, Melodie Munier, Nicolas Foray
Summary: This study investigated the impact of cellular models and individual factors on DNA recognition and repair in human fibroblasts and mammary epithelial cells exposed to chest CT scan conditions. The results showed that CT scan may lead to an increase in unrepaired DNA damage, particularly in radiosensitive/susceptible individuals.
EUROPEAN RADIOLOGY EXPERIMENTAL
(2022)
Letter
Rehabilitation
Julien Roger, Frederic Chauvin, Antoine Bertani, Frederic Rongieras, Thierry Vitry, Francois Le Moigne, Alain Drouet
ANNALS OF PHYSICAL AND REHABILITATION MEDICINE
(2017)
Article
Radiology, Nuclear Medicine & Medical Imaging
Slimane Tounekti, Mahdi Alizadeh, Devon Middleton, James S. Harrop, Bassem Hiba, Laura Krisa, Choukri Mekkaoui, Feroze B. Mohamed
Summary: This study proposes and demonstrates a new method combining reduced field-of-view strategy with phase segmented EPI to address geometric distortion in post-operative DTI scans of patients with metal implants. The results show that the new method outperforms traditional techniques in reducing distortion.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Silvia Minosse, Eliseo Picchi, Valentina Ferrazzoli, Noemi Pucci, Valerio Da Ros, Raffaella Giocondo, Roberto Floris, Francesco Garaci, Francesca Di Giuliano
Summary: The aim of this study was to investigate the variation of DCE-MRI-derived kinetic parameters in brain tumors as a function of acquisition time. The results showed that K-ep and V-e were time-dependent and required longer scan times to obtain reliable parameter values, while K-trans was time-independent and remained the same in all acquisition times, making it a reliable parameter for short acquisition times.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xingmin Guan, Xinheng Zhang, Hsin-Jung Yang, Rohan Dharmakumar
Summary: This study aims to investigate why DIR-prepared dark-blood T2* weighted images have lower SNR, CNR, and diagnostic accuracy for intramyocardial hemorrhage (IMH) detection compared to non-DIR-prepared bright-blood T2* images. Through phantom and animal studies, it was confirmed that the signal loss on DIR-prepared T2* images mainly originates from spin-relaxation during the DIR preparation. Therefore, when used for IMH detection, extra attention should be paid to the SNR of DIR-prepared dark-blood T2* imaging protocols.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Beatriz Laureano, Hassna Irzan, Helen OReilly, Sebastian Ourselin, Neil Marlow, Andrew Melbourne
Summary: Prematurity and preterm stressors have significant effects on the development of infants, especially at earlier gestations. While neonatal care advances have reduced preterm mortality rates, disability rates continue to grow in middle-income settings. Imaging the preterm brain using MR technology has improved our understanding of its development and the affected regions and networks. This research aims to support interventions, improve neurodevelopment, and provide accurate prognoses for preterm infants. This study focuses on the fully developed brain of extremely preterm subjects and examines myelin-related biomarkers to assess long-term effects. The findings suggest altered connectivity and cognitive outcomes in the adult preterm brain.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julian Rauch, Frederik B. Laun, Peter Bachert, Mark E. Ladd, Tristan A. Kuder
Summary: This study presents a method for reducing concomitant field effects in double diffusion encoding (DDE) sequences by adding oscillating gradient pulses. The modified sequences successfully reduced accumulated concomitant phase without significant changes in the original sequence characteristics. The proposed method led to an increase in signal-to-noise ratio (SNR) for phantom and in vivo experiments, supported by simulations.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marlon Bran Lorenzana, Shekhar S. Chandra, Feng Liu
Summary: Sparse reconstruction is important in MRI for reducing acquisition time and improving spatial-temporal resolution. This paper introduces two decoupling techniques for explicit 1D regularization and a combined 1D + 2D reconstruction technique that improves image quality.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yifan Gou, W. Christopher Golden, Zixuan Lin, Jennifer Shepard, Aylin Tekes, Zhiyi Hu, Xin Li, Kumiko Oishi, Marilyn Albert, Hanzhang Lu, Peiying Liu, Dengrong Jiang
Summary: ARTS algorithm improves the reliability of Y-v estimation in noncompliant subjects, enhancing the utility of Y-v as a biomarker for brain diseases.
MAGNETIC RESONANCE IMAGING
(2024)