Article
Psychology, Multidisciplinary
Alasdair G. Morgan, Michael J. Thrippleton, Michael Stringer, Ning Jin, Joanna M. Wardlaw, Ian Marshall
Summary: This study aimed to assess the repeatability, reliability, and conformity of 2D and 4D flow in intracranial vessels. The results showed that PI measurement using 4D flow is repeatable and reliable across intracranial arteries and veins, but absolute flow measurements may be influenced by factors such as slice placement, resolution, and lumen segmentation.
FRONTIERS IN PSYCHOLOGY
(2023)
Review
Medicine, General & Internal
Anders Wahlin, Anders Eklund, Jan Malm
Summary: 4D flow MRI is a valuable technique for studying cerebrovascular diseases, providing crucial information about cerebral arterial venous blood flow and hemodynamic biomarkers indicative of cerebrovascular health. It allows for the investigation of different flow patterns and estimation of brain-wide disturbances in blood flow, which is important for prevention and intervention of cerebrovascular diseases.
JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Clinical Neurology
David C. Lauzier, Samuel J. Cler, Joshua W. Osbun, Arindam R. Chatterjee, Christopher J. Moran, Akash P. Kansagra
Summary: Flow diversion with the pipeline embolization device (PED) for intracranial aneurysms may lead to angiographic stenosis, but dual antiplatelet therapy (DAPT) can effectively prevent stenosis progression and cerebral ischemia.
WORLD NEUROSURGERY
(2022)
Article
Multidisciplinary Sciences
Shanmukha Srinivas, Evan Masutani, Alexander Norbash, Albert Hsiao
Summary: This study evaluated the impact of background phase errors on cerebrovascular flow volume measurements and assessed the effectiveness of manual image-based correction. It also explored the potential of a convolutional neural network (CNN) to directly infer the phase-error correction field. The results showed that manual correction improved the correlation and reduced the variance of flow measurements. The CNN correction was found to be non-inferior to manual correction, indicating its potential for fully automating phase error correction.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Akos Varga-Szemes, Moritz Halfmann, U. Joseph Schoepf, Ning Jin, Anton Kilburg, Danielle M. Dargis, Christoph Duber, Amir Ese, Gilberto Aquino, Fei Xiong, Karl-Friedrich Kreitner, Michael Markl, Tilman Emrich
Summary: This study compared conventional and compressed sensing (CS) based highly accelerated 4D flow imaging in intracardiac flow measurements. The results showed that CS acceleration significantly reduced the acquisition time and had good agreement with conventional acceleration in most measurements. However, CS technique showed underestimation errors in diastolic function evaluation.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
John W. Cerne, Ashitha Pathrose, Daniel Z. Gordon, Roberto Sarnari, Manik Veer, Julie Blaisdell, Bradley D. Allen, Ryan Avery, Michael Markl, Ann Ragin, James C. Carr
Summary: Four-dimensional flow MRI can be used to assess pulmonary hypertension patients' conditions and vascular resistance, showing good discriminative ability among different subgroups of PH.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Multidisciplinary Sciences
Pietro Dirix, Stefano Buoso, Eva S. Peper, Sebastian Kozerke
Summary: This study proposes a method to synthesize patient-specific 4D flow MRI datasets of turbulent flow paired with ground truth flow data for training of inference methods. The results demonstrate the importance of paired ground truth and 4D flow MRI data for accurately assessing turbulent flow inference using 4D flow MRI exams.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Yajie Wang, Jie Sun, Rui Li, Peng Liu, Xian Liu, Jiansong Ji, Chunmiao Chen, Yu Chen, Haikun Qi, Yunduo Li, Longhui Zhang, Luqiong Jia, Fei Peng, Mingzhu Fu, Yishi Wang, Min Xu, Chunli Kong, Shuiwei Xia, Xiaole Wang, Le He, Qiang Zhang, Zhensen Chen, Aihua Liu, Youxiang Li, Ming Lv, Huijun Chen
Summary: In this study, the spatial relationship between hemodynamic forces and aneurysm wall permeability in unruptured saccular intracranial aneurysms was investigated. It was found that aneurysm wall permeability varied between aneurysms and within the same aneurysm, showing spatial heterogeneity. Higher permeability was associated with lower wall shear stress, indicating a potential link between aneurysm wall remodeling and hemodynamic factors.
JOURNAL OF NEUROLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julian A. J. Richter, Tobias Wech, Andreas M. Weng, Manuel Stich, Ning Jin, Aleksander Kosmala, Thorsten A. Bley, Herbert Kostler
Summary: This study investigates the acceleration potential of wave-CAIPI for 4D flow MRI, and finds that it enhances the precision of flow parameters while maintaining image quality. Comparison with standard Cartesian/2D-CAIPI sampling shows smaller deviations in flow parameters and reduced qualitative discrepancies in hemodynamic flow patterns when using wave-CAIPI.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Neuroimaging
Siming Gui, Xiheng Chen, Dachao Wei, Dingwei Deng, Wei You, Xiangyu Meng, Jian Lv, Junqiang Feng, Yudi Tang, Shu Yang, Ting Chen, Peng Liu, Huijian Ge, Hengwei Jin, Xinke Liu, Yuhua Jiang, Wei Feng, Youxiang LI
Summary: Flow diverters have greatly improved the treatment of intracranial aneurysms, but the delayed complications associated with their use are not well understood. This study evaluated the occurrence, severity, clinical outcomes, risk factors, and dynamic changes of in-stent stenosis (ISS) after treatment with a Pipeline embolization device (PED). The results show that ISS is a common, benign, and self-limiting complication of PED implantation in the Chinese population.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Sung Won Youn, Jongmin Lee
Summary: Considering the interaction between flow and vessel wall, hemodynamic assessment of the neurovascular system provides a comprehensive solution for both diagnosis and management, adding prognostic significance. 4D flow MRI techniques have advantages in evaluating neurovascular diseases by visualizing and measuring flow parameters while simultaneously assessing vessel wall conditions.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Clinical Neurology
Wei You, Jian Lv, Zifan Li, Xiheng Chen, Dingwei Deng, Yudi Tang, Youxiang Li, Yong Sun, Yuhua Jiang
Summary: In-stent stenosis (ISS) is a common complication after pipeline embolization device (PED) implantation for intracranial aneurysms (IAs). Most cases of ISS are mild, with only a small number of patients experiencing severe stenosis. Younger age and longer procedure duration are predictors of a higher likelihood of ISS severity.
FRONTIERS IN NEUROLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Dahan Kim, Mu-Lan Jen, Laura B. Eisenmenger, Kevin M. Johnson
Summary: This study investigates the acceleration of 4D-flow MRI using a convolutional neural network, which can generate three-directional velocity maps with small errors from only three flow encodings. By optimizing the loss functions, the correlation of velocity can be improved. The network maintains a high correlation with ground truth data and acts as a denoising tool when applied to highly accelerated data.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jos J. M. Westenberg, Hans C. Assen, Pieter J. den Boogaard, Jelle J. Goeman, Hicham Saaid, Jason Voorneveld, Johan Bosch, Sasa Kenjeres, Tom Claessens, Pankaj Garg, Marc Kouwenhoven, Hildo J. Lamb
Summary: Velocity and flow rates are inaccurate for 4DEPI with EPI factor 5 when flow is parallel to the readout or blip phase-encoding gradient. However, mean differences in flow rate, voxel-based speed, and spatio-temporal median speed were acceptable (<= 10%) when comparing 4DEPI to 4DGRE for intracardiac flow in healthy volunteers.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Miaoqi Zhang, Fei Peng, Yunduo Li, Le He, Aihua Liu, Rui Li
Summary: This study investigated the interaction between morphology and hemodynamics of intracranial aneurysms using BB-MRI and 4D flow MRI. The findings revealed significant correlations between mWT, WSSavg, and Flow(IA) with the size and SR of IAs, which remained consistent after adjusting for confounding factors through multivariate analysis. There is potential for these imaging modalities to serve as non-invasive biomarkers for IA assessments and contribute to a more comprehensive understanding of IA mechanisms.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Slimane Tounekti, Mahdi Alizadeh, Devon Middleton, James S. Harrop, Bassem Hiba, Laura Krisa, Choukri Mekkaoui, Feroze B. Mohamed
Summary: This study proposes and demonstrates a new method combining reduced field-of-view strategy with phase segmented EPI to address geometric distortion in post-operative DTI scans of patients with metal implants. The results show that the new method outperforms traditional techniques in reducing distortion.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Silvia Minosse, Eliseo Picchi, Valentina Ferrazzoli, Noemi Pucci, Valerio Da Ros, Raffaella Giocondo, Roberto Floris, Francesco Garaci, Francesca Di Giuliano
Summary: The aim of this study was to investigate the variation of DCE-MRI-derived kinetic parameters in brain tumors as a function of acquisition time. The results showed that K-ep and V-e were time-dependent and required longer scan times to obtain reliable parameter values, while K-trans was time-independent and remained the same in all acquisition times, making it a reliable parameter for short acquisition times.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xingmin Guan, Xinheng Zhang, Hsin-Jung Yang, Rohan Dharmakumar
Summary: This study aims to investigate why DIR-prepared dark-blood T2* weighted images have lower SNR, CNR, and diagnostic accuracy for intramyocardial hemorrhage (IMH) detection compared to non-DIR-prepared bright-blood T2* images. Through phantom and animal studies, it was confirmed that the signal loss on DIR-prepared T2* images mainly originates from spin-relaxation during the DIR preparation. Therefore, when used for IMH detection, extra attention should be paid to the SNR of DIR-prepared dark-blood T2* imaging protocols.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Beatriz Laureano, Hassna Irzan, Helen OReilly, Sebastian Ourselin, Neil Marlow, Andrew Melbourne
Summary: Prematurity and preterm stressors have significant effects on the development of infants, especially at earlier gestations. While neonatal care advances have reduced preterm mortality rates, disability rates continue to grow in middle-income settings. Imaging the preterm brain using MR technology has improved our understanding of its development and the affected regions and networks. This research aims to support interventions, improve neurodevelopment, and provide accurate prognoses for preterm infants. This study focuses on the fully developed brain of extremely preterm subjects and examines myelin-related biomarkers to assess long-term effects. The findings suggest altered connectivity and cognitive outcomes in the adult preterm brain.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julian Rauch, Frederik B. Laun, Peter Bachert, Mark E. Ladd, Tristan A. Kuder
Summary: This study presents a method for reducing concomitant field effects in double diffusion encoding (DDE) sequences by adding oscillating gradient pulses. The modified sequences successfully reduced accumulated concomitant phase without significant changes in the original sequence characteristics. The proposed method led to an increase in signal-to-noise ratio (SNR) for phantom and in vivo experiments, supported by simulations.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marlon Bran Lorenzana, Shekhar S. Chandra, Feng Liu
Summary: Sparse reconstruction is important in MRI for reducing acquisition time and improving spatial-temporal resolution. This paper introduces two decoupling techniques for explicit 1D regularization and a combined 1D + 2D reconstruction technique that improves image quality.
MAGNETIC RESONANCE IMAGING
(2024)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yifan Gou, W. Christopher Golden, Zixuan Lin, Jennifer Shepard, Aylin Tekes, Zhiyi Hu, Xin Li, Kumiko Oishi, Marilyn Albert, Hanzhang Lu, Peiying Liu, Dengrong Jiang
Summary: ARTS algorithm improves the reliability of Y-v estimation in noncompliant subjects, enhancing the utility of Y-v as a biomarker for brain diseases.
MAGNETIC RESONANCE IMAGING
(2024)
