Proposing a scientific confidence framework to help support the application of adverse outcome pathways for regulatory purposes

Published 2015 View Full Article

Authors

Keywords

Scientific confidence framework (SCF), Adverse outcome pathway (AOP), Mode of action (MoA), Integrated approaches to testing and assessment (IATA), (Q)SAR, Read-across, Exposure:activity ratio (EAR)

Journal

REGULATORY TOXICOLOGY AND PHARMACOLOGY

Volume 71, Issue 3, Pages 463-477

Publisher

Elsevier BV

Online

2015-02-21

DOI

10.1016/j.yrtph.2015.02.011

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