Article
Materials Science, Multidisciplinary
Osman Konuray, Sasan Moradi, Adria Roig, Xavier Fernandez-Francos, Xavier Ramis
Summary: In order for covalent adaptable networks to be fully recyclable, they need to overcome all topological restrictions and flow. A statistically based method showed that the relaxation of stress in disulfide-containing thiol-ene polymers is closely related to the fraction of permanent cross-links. Even with low disulfide content, the materials can be recycled at moderate temperatures without losing tensile properties by triggering transesterification reactions through increased reprocessing temperature, due to the presence of ester bonds.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Polymer Science
Mustafa Selman Yavuz, Murat Citir
Summary: Two novel covalent organic networks, TEPN-1 and TEPN-2, were synthesized and analyzed for solvent uptake capacity. TEPN-1 showed higher swelling adsorption ratio with chloroform and DCM compared to TEPN-2. Both TEPN-1 and TEPN-2 exhibited minimal water uptake and efficient adsorption for various organic solvents.
Article
Polymer Science
Logan D. Dugas, William D. Walker, Rahul Shankar, Keely S. Hoppmeyer, Travis L. Thornell, Sarah E. Morgan, Robson F. Storey, Derek L. Patton, Yoan C. Simon
Summary: This work describes a photopolymerized thiol-ene-based vitrimer that combines stability, healability, and reprocessability. The introduction of excess primary amines enables the degradation and regeneration of the vitrimer. Photopolymerization provides unique control over the network topology, facilitating further investigation of vitrimer properties.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Engineering, Environmental
Yixiang Chen, Xueli Fu, Yu Jiang, Wanqi Feng, Dan Yu, Wei Wang
Summary: Recently, the flexible electronics based on Ti3C2Tx MXene have gained significant attention in the fields of artificial health diagnosis, military security, and human-machine interaction. In the context of long-term health detection, there is a need for strain sensors with high sensitivity, durability, and multifunctionality. However, the unevenness and low fastness of MXene and stretchable nanofibers result in poor sensitivity and durability. Therefore, a strong interface that combines two-dimensional MXene nanosheets uniformly along one-dimensional nanofibers has been proposed to enhance the sensing performances.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Zijun Gao, Yang You, Qin Chen, Michael North, Haibo Xie
Summary: It is important for sustainable development to produce degradable thiol-ene networks from bio-based monomers using eco-friendly processes. In this study, tunable and degradable thiol-ene crosslinked networks were prepared from renewable vanillin and multifunctional thiols. The networks exhibited varied properties by incorporating different crosslinkers, and they showed good transparency and degradability.
Article
Polymer Science
Shota Iino, Shigeki Sobu, Kazuhiro Nakabayashi, Sadaki Samitsu, Hideharu Mori
Summary: A series of polythioethers with spirobifluorene skeletons were successfully synthesized by a thiol-ene reaction, exhibiting high refractive index, transparency, and thermal stability. The manipulation of refractive index and Abbe number through reacting different dithiol components with DASF allows for the design of molecular structures suitable for nano- and microfabrication, achieving high transparency, flexibility, and thermal stability.
Article
Polymer Science
Nicholas J. Bongiardina, Shafer M. Soars, Maciej Podgorski, Christopher N. Bowman
Summary: This study evaluated radical-disulfide exchange reactions in thiol-ene-disulfide networks using different thiol and disulfide containing monomers. The results show that the stress relaxation rate in these networks can be controlled by changing the thiol-disulfide stoichiometry or the disulfide type. The combination of different thiol and disulfide monomers also influences the polymerization rate of the thiol-ene reaction.
Article
Polymer Science
Aneta Lewandowska, Piotr Gajewski, Katarzyna Szczesniak, Zbigniew Fojud, Mariola Robakowska, Andrzej Skrzypczak, Adam Voelkel, Agnieszka Marcinkowska
Summary: This work reports the synthesis of polymerizable ionic liquids (PILs) and the preparation of ionogels using thiol-ene photopolymerization. The ionogels prepared with the PILs showed excellent mechanical properties, high ionic conductivity, and thermal stability. The structure of the PILs affected the polymerization kinetics and properties of the ionogels.
Article
Chemistry, Organic
Erjun Hao, Binghui Lu, Yonghong Liu, Tianxiao Yang, Huaipu Yan, Xiaobo Ding, Yunhe Jin, Lei Shi
Summary: Recently, radical difunctionalization of 1,3-butadiene has gained attention as a strategy to increase molecular complexity. In this study, a novel approach combining radical thiol-ene chemistry with Ti-III catalysis under visible light conditions was developed for a three-component aldehyde allylation using 1,3-butadiene as an allyl group source. This sustainable and straightforward method allows for the rapid production of diverse allylic 1,3-thioalcohols with exceptional regio- and diastereoselectivity.
Article
Polymer Science
Jake A. Muldoon, Michael D. Garrison, Markku A. Savolainen, Benjamin G. Harvey
Summary: Cardanol, a low-cost component of cashew nut shell oil, was converted to a cyanate ester resin and blended with a trifunctional thiol. UV light irradiation allowed for ambient temperature cure and enhanced cross-linking. This material may have potential applications as a toughener for rigid cyanate esters or self-healing materials.
Article
Biochemistry & Molecular Biology
Quinten Thijssen, Laurens Parmentier, Kevin Van Holsbeeck, Steven Ballet, Sandra Van Vlierberghe
Summary: In order to imitate the cell adhesion ability of nature, researchers often modify the surface of PCL with nature-derived polymers or functionalize it using a cell-binding motif. However, these surface modifications are limited to the surface, require multiple steps, and involve harsh conditions. In this study, a one-step strategy is proposed where thiol-ene chemistry is used to crosslink alkene-functionalized PCL with a multifunctional thiol, and a cysteine coupling site is used to covalently bind the cell-binding motif C(-linker-)RGD throughout the PCL networks during crosslinking. The influence of different linkers between the cysteine coupling site and the cell-binding motif RGD is investigated and the functionalization is evaluated using static contact angle measurements and X-ray photoelectron spectroscopy. Successful introduction of cell adhesiveness is demonstrated by seeding fibroblasts onto the functionalized PCL networks.
Article
Materials Science, Multidisciplinary
Yong Lu, Qizheng Li, Zhicheng Zhang, Xiao Hu
Summary: In this study, two magnolol-based polymers were designed and synthesized for high-performance polymer dielectrics. The polymers showed excellent thermal, mechanical, and dielectric properties, making them promising materials for energy storage.
MATERIALS & DESIGN
(2022)
Article
Polymer Science
Murat Tonga, Lang Wei
Summary: This study utilized thiol-ene chemistry to develop flexible thermoelectric composites based on carbon nanotubes. The use of non-conjugated linkers was found to result in better thermoelectric performance, and the materials exhibited n-type semiconducting behavior without the need for doping, achieving high power factors.
Article
Chemistry, Medicinal
Hao-Zheng Li, Xiao-Xia Shao, Li-Li Shou, Ning Li, Ya-Li Liu, Zeng-Guang Xu, Zhan-Yun Guo
Summary: In this study, a novel approach was developed to prepare esterase-resistant ghrelin analogs using photoinduced thiolene click chemistry. Among the analogs synthesized, analog 11 exhibited higher stability in serum and retained full activity compared to native human ghrelin.
ACS MEDICINAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Medicinal
Hao-Zheng Li, Xiao-Xia Shao, Li-Li Shou, Ning Li, Ya-Li Liu, Zeng-Guang Xu, Zhan-Yun Guo
Summary: In this study, a novel method was developed to prepare esterase-resistant ghrelin analogs using photoinduced thiol-ene click chemistry. Among the 11 synthesized analogs, analog 11 generated by reacting with 2-methyl-1-octene exhibited higher stability in serum and retained full activity compared to native human ghrelin.
ACS MEDICINAL CHEMISTRY LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Pohlee Cheah, Paul Brown, Jing Qu, Bin Tian, Derek L. Patton, Yongfeng Zhao
Summary: This paper presents a facile one-pot strategy for versatile surface functionalization and precise size control of iron oxide nanoparticles, which can be applied in biomedical fields. The synthesis method allows surface modification with different coating materials to introduce new surface functionalities. The nanoparticles with surface ligands exhibit outstanding stability and improved sensitivity in aqueous solution, showing potential for biological applications.
Article
Chemistry, Multidisciplinary
Naneki C. McCallum, Florencia A. Son, Tristan D. Clemons, Steven J. Weigand, Karthikeyan Gnanasekaran, Claudia Battistella, Brooke E. Barnes, Hashanthi Abeyratne-Perera, Zofia E. Siwicka, Christopher J. Forman, Xuhao Zhou, Martin H. Moore, Daniel A. Savin, Samuel Stupp, Zheng Wang, Gary J. Vora, Brandy J. Johnson, Omar K. Farha, Nathan C. Gianneschi
Summary: Research on artificial allomelanin analogues reveals high intrinsic microporosity and high BET surface area achievable through a simplified method. These synthetic allomelanin particles exhibit functions such as adsorbing ammonia and nerve agent simulants, as well as preventing agent breakthrough on breathable fabrics. Compared to naturally derived fungal melanin, synthetic analogues have higher porosity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Nanoscience & Nanotechnology
Karyn Pounds, Suguna Jairam, Hanxi Bao, Shanyu Meng, Lin Zhang, Scarlett (Arencibia) Godinez, Daniel A. Savin, William Pelletier, Melanie J. Correll, Zhaohui Tong
Summary: Research is focused on creating a responsive packaging material that can detect food spoilage in real-time by monitoring changes in pH, aiming to reduce food waste.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Editorial Material
Chemistry, Physical
Daniel A. Savin, Joseph E. Subotnik, Kieron Burke, Evelyn M. Goldfield, Marshall D. Newton, John F. Stanton
JOURNAL OF PHYSICAL CHEMISTRY A
(2021)
Article
Polymer Science
Katrina M. Knauer, Joshua C. Speros, Lisa K. Kemp, Daniel A. Savin, Zhenan Bao, Geoffrey W. Coates, Thomas H. Epps, Craig J. Hawker, Jennifer J. Le Roy, Molly Morse, Oliver Yu
Summary: Launching a startup company is compared to synthesizing a new molecule, requiring determination and creativity. Success in synthesis often relies more on perseverance than the original plan. The authors distilled their experiences to highlight essential topics for scientific entrepreneurs.
Article
Environmental Sciences
Arianna J. Partow, Shanyu Meng, Alexander J. Wong, Daniel A. Savin, Zhaohui Tong
Summary: This study successfully fabricated a highly porous, mechanically strong, and stable aerogel using low-cost lignin as the starting material. The aerogel exhibits controllable micropore structure and achieves quick and efficient adsorption for oil and toxic solvents, and can be reused multiple times.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Multidisciplinary
Amanda Pritzlaff, Guillaume Ferre, Emma Mulry, Ling Lin, Niloofar Gopal Pour, Daniel A. Savin, Michael E. Harris, Matthew T. Eddy
Summary: PEGylation is a promising method to improve protein stability, but the underlying mechanism is not well understood. This study used a structural and biophysical approach to investigate the effects of PEGylation on the carbohydrate recognition domain of human galectin-3. The results revealed the potential role of charged residues in PEG localization and provided insights for the rational design of conjugates.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Polymer Science
Logan D. Dugas, William D. Walker, Rahul Shankar, Keely S. Hoppmeyer, Travis L. Thornell, Sarah E. Morgan, Robson F. Storey, Derek L. Patton, Yoan C. Simon
Summary: This work describes a photopolymerized thiol-ene-based vitrimer that combines stability, healability, and reprocessability. The introduction of excess primary amines enables the degradation and regeneration of the vitrimer. Photopolymerization provides unique control over the network topology, facilitating further investigation of vitrimer properties.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Nanoscience & Nanotechnology
Seid Yimer Abate, Surabhi Jha, Guorong Ma, Jawnaye Nash, Nihar Pradhan, Xiaodan Gu, Derek Patton, Qilin Dai
Summary: The commercialization of perovskite solar cells is hindered by their poor long-term stability. In this study, tetradodecylammonium bromide (TDDAB) was used as a postsurface modifier to suppress the density of defects in the perovskite film. The modified device showed significantly improved power conversion efficiency and enhanced moisture resistance.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Editorial Material
Polymer Science
Xiaodan Gu, Derek Patton
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Alejandro Guillen Obando, Mark Robertson, Paul Smith, Surabhi Jha, Derek L. Patton, Zhe Qiang
Summary: Capturing CO2 from industrial waste streams is crucial for achieving global carbon-neutrality. Solid sorbents, compared with liquid sorbents, have advantages such as longer lifetime and reduced energy consumption. This study demonstrates the use of a commodity polymer for producing hierarchically porous sulfur-doped carbons for CO2 capture, providing a viable method for industrial-scale manufacturing of porous carbons with high capture performance and low-cost precursors.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Polymer Science
Georg M. Scheutz, Justine Elgoyhen, Kyle C. Bentz, Yening Xia, Hao Sun, Junpeng Zhao, Daniel A. Savin, Brent S. Sumerlin
Summary: This study demonstrates the photoinduced intrachain crosslinking of coumarin-containing copolymers in various organic solvents, with solvophobicity-driven crosslinking kinetics and chain compaction facilitating the synthesis of single-chain nanoparticles.
Article
Polymer Science
Christopher B. Keller, Susan E. Walley, Curtis W. Jarand, Jibao He, Muhammad Ejaz, Daniel A. Savin, Scott M. Grayson
Summary: By grafting linear-bottlebrush amphiphilic copolymers onto the surface of silica nanoparticles, nanoparticle micelles with the ability to encapsulate and stabilize non-polar structures in aqueous media were successfully formed. These nanoparticles not only enhance oil encapsulation, but also provide an alternative dispersant system to address oil pollution in the environment.
Article
Polymer Science
Oluwapelumi O. Kareem, Farzin Rahmani, Jason A. Hyman, Christopher B. Keller, Melissa A. Pasquinelli, Daniel A. Savin, Scott M. Grayson
Summary: Dendrimers have a perfect structure fidelity with high density of functional groups in the outer shell, maintaining relatively stable size across different solvents. In contrast, linear polymers of similar molecular weight may exhibit greater size variation due to solvent-polymer interactions.
Article
Materials Science, Multidisciplinary
Witold K. Fuchs, Catherine Sarantes, Nathaniel Prine, Xiaodan Gu, Derek L. Patton, Jeffrey Wiggins
Summary: Research showed that epoxies containing PPO groups form a phosphate layer on the surface after exposure to AO, leading to a significant reduction in erosion rates. The resistance to AO of these materials can be easily tuned by synthetic incorporation of monomers with varying phosphorus concentrations.
ACS APPLIED POLYMER MATERIALS
(2021)