Article
Pharmacology & Pharmacy
Anna Puscion-Jakubik, Anita Mielech, Dominika Abramiuk, Malgorzata Iwaniuk, Monika Grabia, Joanna Bielecka, Renata Markiewicz-Zukowska, Katarzyna Socha
Summary: Research shows that some dietary supplements may be contaminated with mercury, posing potential risks to human health, especially kidney and nervous system damage. Therefore, monitoring of mercury content in dietary supplements, particularly those aimed at lowering blood glucose and enhancing vitality, is necessary to ensure consumer safety.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Chemistry, Applied
Joanna Brzezinska-Rojek, Malgorzata Rutkowska, Justyna Osko, Piotr Konieczka, Magdalena Prokopowicz, Malgorzata Grembecka
Summary: This study determined the total mercury concentrations in beetroot-based dietary supplements and conventional and organic beetroots. The results showed that the analysed dietary supplements did not pose a significant risk for consumers in terms of mercury contamination.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Review
Food Science & Technology
Amin Gasmi, Geir Bjorklund, Pavan Kumar Mujawdiya, Yuliya Semenova, Alexandru Dosa, Salva Piscopo, Joeri J. Pen, Asma Gasmi Benahmed, Daniel Ovidiu Costea
Summary: Bariatric surgery is an effective method for significant weight loss in patients who have not achieved weight loss through pharmacological interventions. Post-surgery, sustained weight loss offers metabolic advantages and improves glucose and lipid metabolism. However, bariatric surgery is associated with deficiencies in vitamins and minerals, requiring monitoring and supplementation.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Maoping Duan, Tian Li, Bo Liu, Shuhua Yin, Jiachen Zang, Chenyan Lv, Guanghua Zhao, Tuo Zhang
Summary: This review examines the importance of zinc nutrition for human health, focusing on the relationship between zinc deficiency and various diseases, particularly their impact on the immune system and COVID-19. It also explores the potential of food-derived zinc-binding compounds as supplements and discusses the methods and mechanisms of maintaining zinc homeostasis.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Medicine, Legal
Nicolas Fabresse, Laurie Gheddar, Pascal Kintz, Adeline Knapp, Islam Amine Larabi, Jean-Claude Alvarez
Summary: Substandard and counterfeit drugs are a growing global problem. Analysis of pharmaceuticals and dietary supplements seized from the black market among bodybuilders in France revealed a significant proportion of products with quality issues.
FORENSIC SCIENCE INTERNATIONAL
(2021)
Review
Nutrition & Dietetics
Moriah Mallick, Chloe Briana Camacho, Jana Daher, Dalia El Khoury
Summary: Dietary supplements are commonly used by athletes for health and performance enhancement, but they may unknowingly consume prohibited substances due to contamination. Athletes often rely on unreliable sources of information and lack knowledge of supplement regulations.
Review
Food Science & Technology
Hui Duan, Jiani Pan, Min Guo, Jinwei Li, Leilei Yu, Liuping Fan
Summary: Dietary intervention is a safe, broad-spectrum, and low-cost strategy for slowing aging. It regulates nutrient-sensing pathways, gut microbiota, metabolism, and immunity. Different dietary patterns and supplements, as well as the proportion of macronutrients, have varying effects on aging.
FOOD RESEARCH INTERNATIONAL
(2022)
Review
Medicine, General & Internal
Mariano Andres, Francisca Sivera, Rachelle Buchbinder, Jordi Pardo Pardo, Loreto Carmona
Summary: The efficacy and safety of dietary supplements for people with chronic gout are still controversial. Currently, the effects of using protein supplements or vitamin C for gout patients are not significant, which may not have a great clinical relevance.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Review
Medicine, Research & Experimental
Shuo Huang, Baowen Qi, Ling Yang, Xue Wang, Jing Huang, Ya Zhao, Yonghe Hu, Wenjing Xiao
Summary: Endocrine therapy has been effective in treating breast cancer, but it still faces challenges such as drug resistance and individual discrepancy. There is a demand for novel preventive and therapeutic modalities to decrease the incidence and mortality rate of breast cancer. G protein-coupled estrogen receptor (GPER) is a potential target for breast cancer prevention and treatment. This review discusses the possible mechanisms of GPER pathways and proposes the development of phytoestrogens-based dietary supplements against breast cancer.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Oncology
Paul Gougis, Marc Hilmi, Arthur Geraud, Olivier Mir, Christian Funck-Brentano
Summary: Herbs, food, and dietary supplements can interact with anticancer drugs through cytochrome P450 isoforms, affecting drug metabolism. Among 261 HFDS studied, 21 were found to interact with CYP3A4, a key metabolic pathway for many anticancer drugs. This interaction can have implications for the efficacy and safety of cancer treatment.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
(2021)
Review
Pharmacology & Pharmacy
Lulu Gao, Xudong Liu, Xiaoyan Luo, Xiaofan Lou, Pusen Li, Xian Li, Xiaomeng Liu
Summary: Aging is influenced by various factors and has led to an increase in aging-related diseases globally. Natural products have been used for a long time and have been proven to have antiaging effects through various cellular pathways. This article reviews several natural products with potential antiaging properties and highlights their cellular and molecular mechanisms.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Xiangming Ji, Hongwei Yao, Maureen Meister, Douglas S. Gardenhire, Huanbiao Mo
Summary: COPD is a leading cause of death worldwide, characterized by emphysema and chronic bronchitis, with smoking as a significant risk factor in developed countries. Chronic inflammation contributes to disease progression and comorbidities. Tocotrienols show potential as anti-inflammatory agents in COPD management.
Review
Biotechnology & Applied Microbiology
C. A. Laamanen, S. M. Desjardins, G. N. A. Senhorinho, J. A. Scott
Summary: Microalgae, as an abundant and diverse resource, can be used in the food and dietary supplements industry to address growing pressures, but challenges in harvesting technologies and economics continue to limit large-scale production.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2021)
Article
Food Science & Technology
Joanna Brzezinska, Adrian Szewczyk, Justyna Brzezicha, Magdalena Prokopowicz, Malgorzata Grembecka
Summary: A study found that in the European Union, several beetroot-based dietary supplements did not meet USP requirements, with some taking over 30 minutes to disintegrate, and some failing the friability test due to cracking. The variations in hardness values and iron content among manufacturers highlighted the need for better quality control in dietary supplements before they are introduced to the European market.
Article
Nutrition & Dietetics
Joanna Brzezinska-Rojek, Malgorzata Rutkowska, Justyna Brzezicha, Piotr Konieczka, Magdalena Prokopowicz, Malgorzata Grembecka
Summary: This study analyzed the composition of 22 elements in beetroot and its supplements. The results showed that beetroot is a significant source of elements, while supplements only contain trace amounts. Some products were found to be contaminated with toxic elements. Factor and cluster analysis helped differentiate beetroot and its supplements.
Article
Environmental Sciences
Mikolaj Dabrowski, Anetta Ziola-Frankowska, Marcin Frankowski, Jacek Kaczmarczyk, Lukasz Kubaszewski
Summary: Changes in bone metabolism and associated trace element content can explain the role of analyzed elements in different stages of hip osteoarthritis. Variations in trace element content and correlation in the hip joint have an impact on metabolism depending on the severity of degenerative changes.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Materials Science, Multidisciplinary
M. Nowak, A. Tolinska, L. Marciniak, M. Skrobanska, B. Tylkowski, M. Frankowski, M. T. Kaczmarek, R. Jastrzab
Summary: This study synthesized silver nanoparticles using D-glucose reduction and evaluated their characteristics. The results showed that D-glucose-reduced silver nanoparticles possessed excellent antibacterial properties, making them suitable for daily soap production.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Adam Kubiak, Zuzanna Bielan, Aleksandra Bartkowiak, Elzbieta Gabala, Marcin Frankowski, Maciej Zalas, Katarzyna Siwinska-Ciesielczyk, Marcin Janczarek, Teofil Jesionowski
Summary: The multifunctional TiO2-ZnO heterostructures were prepared using a two-stage microwave method and exhibited high photocatalytic activity in phenol degradation and significantly improved photovoltaic parameters in DSSC cells.
MATERIALS RESEARCH BULLETIN
(2022)
Article
Biology
Mikolaj Dabrowski, Anetta Ziola-Frankowska, Marcin Frankowski, Przemyslaw Daroszewski, Agnieszka Szymankiewicz-Szukala, Lukasz Kubaszewski
Summary: This study evaluated the content of macroelements in the femoral bone tissue of patients with hip osteoarthritis and examined its correlation with age and sex. The results showed that the reduction of macroelements in the bone tissue was more pronounced in the cortical bone of female patients under 60 years old and began in the seventh decade of life for male patients.
Article
Engineering, Environmental
Lukasz Wolski, Kamila Sobanska, Grzegorz Nowaczyk, Marcin Frankowski, Mariusz Pietrowski, Marcin Jarek, Mateusz Rozmyslak, Piotr Pietrzyk
Summary: This study investigates the influence of phosphate dopants on the reactivity of Nb2O5-based nanomaterials in the combined catalytic activation of H2O2 and the elimination of methylene blue (MB) from an aqueous solution. The results show that phosphate doping significantly enhances the ability of Nb2O5 to activate H2O2, as well as to adsorb and degrade MB. Under strongly acidic conditions, the modified catalysts with a Nb/P molar ratio of 5/1 exhibit a 6-fold increase in efficiency for MB removal compared to the parent Nb2O5.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Multidisciplinary Sciences
K. A. Lueders, L. Braunschweig, A. Ziola-Frankowska, A. Stojek, D. Jakkielska, A. Wichmann, G. H. Dihazi, F. Streit, S. E. Guesewell, T. C. Truee, S. Lueders, J. Schlie, K. Tsaknakis, H. M. Lorenz, M. Frankowski, A. K. Hell
Summary: Magnetically controlled growing rods (MCGRs) are an effective treatment method for early-onset scoliosis (EOS). This study investigates the correlation between the amount of metal loss and titanium levels in blood during MCGR treatment, as well as influencing factors for metal wear. The study found that material loss on the MCGRs showed a positive correlation to titanium blood plasma values.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Tina Pekec, Jaroslaw Lewandowski, Alicja A. Komur, Daria Sobanska, Yanwu Guo, Karolina Switonska-Kurkowska, Jedrzej M. Malecki, Abhishek Anil Dubey, Wojciech Pokrzywa, Marcin Frankowski, Maciej Figiel, Rafal Ciosk
Summary: This study uncovers a regulatory axis involving DAF-16/FoxO and PQM-1 that enhances the resistance of nematodes to severe cold. It is found that FTN-1/FTH1 facilitates cold survival by detoxifying iron species that generate reactive oxygen species. The findings suggest that this mechanism can also protect mammalian neurons from cold-induced degeneration, opening a potential avenue for improved treatments of hypothermia.
NATURE COMMUNICATIONS
(2022)
Article
Environmental Sciences
Sara Lehmann-Konera, Marek Ruman, Marcin Frankowski, Lukasz Ma Larzewski, Krzysztof Raczy, Filip Pawlak, Krystyna Koziol, Zaneta Polkowska
Summary: The study shows that the sediment in the glacier forefield primarily comes from anthropogenic sources, while the metals and metalloids deposited on the Calypsostranda marine terrace come from both natural and anthropogenic sources. The correlation matrix and principal component analysis reveal different primary factors affecting rainfall chemistry at each study site.
Article
Chemistry, Physical
Adam Kubiak, Hubert Fuks, Marcin Frankowski, Anna Szymczyk, Michal Ceglowski
Summary: In this study, TiO2-graphite photocatalysts were synthesized using a one-step in situ microwave procedure, and the influence of graphite content on the crystal structure, surface area development, and optical properties of the photocatalysts was determined. The presence of graphite caused a red shift in the absorption spectra, and a tailor-made LED photoreactor was designed to match the spectrum of the photocatalyst and the light source, resulting in enhanced elimination of sulfamethoxazole. The TiO2-graphite systems showed higher sulfamethoxazole removal efficiency compared to the reference TiO2, and exhibited good reusability, suggesting the potential of this spectral matching approach for wastewater treatment plants.
APPLIED SURFACE SCIENCE
(2023)
Article
Engineering, Environmental
Adam Kubiak, Elzbieta Gabala, Kamila Sobanska, Marcin Frankowski, Piotr Pietrzyk, Piotr Krawczyk, Michal Ceglowski
Summary: Over the past decade, the presence of pharmaceuticals in aquatic environments has been identified as a new environmental hazard. This study developed a customized photocatalytic system using titanium dioxide loaded on carbon fibers to degrade the antibiotic sulfamethoxazole. The results showed that the TiO2-loaded carbon fibers had a high removal efficiency for sulfamethoxazole and could be easily separated after the photo-oxidation process, indicating potential for practical applications.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Environmental Sciences
Danuta Szuminska, Krystyna Koziol, Sergey R. Chalov, Vasilii A. Efimov, Marcin Frankowski, Sara Lehmann-Konera, Zaneta Polkowska
Summary: The impact of permafrost thaw on river and lake water chemistry is a complex problem that needs to be considered in the context of legacy permafrost shrinkage and the interference of the deepening active layer with newly deposited anthropogenic contaminants.
LAND DEGRADATION & DEVELOPMENT
(2023)
Article
Environmental Sciences
Filip Pawlak, Krystyna Koziol, Marcin Frankowski, Lukasz Nowicki, Christelle Marlin, Anna Maria Sulej-Suchomska, Zaneta Polkowska
Summary: In this study, the researchers investigated whether sea spray can act as a secondary source of chlorinated persistent organic pollutants (POPs) in the terrestrial Arctic. They analyzed polychlorinated biphenyls and organochlorine pesticides concentrations in fresh snow and seawater samples, and conducted isotopic analysis to support their interpretations. The results show a significant correlation between POPs concentrations and proximity to the sea, suggesting that sea spray can indeed contribute to the presence of chlorinated POPs in the Arctic.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Dorota Jakkielska, Ioannis Dasteridis, Maciej Kubicki, Marcin Frankowski, Anetta Ziola-Frankowska
Summary: The research aimed to evaluate the impact of various factors on the concentration of 26 elements in Polish wine samples. It was found that white wines had higher levels of certain elements, including Al, Cu, and Fe, while red wines had higher concentrations of Ba, Mn, and Sr. Additionally, the study confirmed that the analyzed elements did not pose a health risk to wine consumers.
Article
Chemistry, Physical
Lukasz Wolski, Kamila Sobanska, Joanna Wolska, Mateusz Rozmyslak, Grzegorz Nowaczyk, Marcin Frankowski, Piotr Pietrzyk
Summary: Understanding the factors affecting the reactivity of gold nanoparticles in catalytic oxidation is important, with a focus on the metal-support interaction. This study showed that the APMS modifier weakens electronic interaction between ZnO and Au NPs, resulting in lower catalase-like activity towards H2O2 but higher efficiency in utilizing H2O2 for oxidation of benzyl alcohol under base-free conditions.
Article
Biochemistry & Molecular Biology
Magdalena Fabjanowicz, Vasil Simeonov, Marcin Frankowski, Wojciech Wojnowski, Justyna Plotka-Wasylka
Summary: This study investigated the correlation between specific compounds in cool-climate country wines, analyzed their elemental composition, and used chemometric analysis. The results revealed specific correlations between different compounds in cool-climate wines.
Article
Medicine, Legal
Fiona Sewell, Ian Ragan, Graham Horgan, David Andrew, Thomas Holmes, Irene Manou, Boris P. Mueller, Tim Rowan, Barbara G. Schmitt, Marco Corvaro
Summary: There are currently three test guidelines for acute oral toxicity studies, but the subjectivity of one guideline may be hindering its wider use. In order to address this, the NC3Rs and EPAA collaborated to analyze historical data and provide recommendations on the recognition of 'evident toxicity'.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)
Article
Medicine, Legal
Michael DeVito, Bas Bokkers, Majorie B. M. van Duursen, Karin van Ede, Mark Feeley, Elsa Antunes Fernandes Gaspar, Laurie Haws, Sean Kennedy, Richard E. Peterson, Ron Hoogenboom, Keiko Nohara, Kim Petersen, Cynthia Rider, Martin Rose, Stephen Safe, Dieter Schrenk, Matthew W. Wheeler, Daniele S. Wikoff, Bin Zhao, Martin van den Berg
Summary: In October 2022, the World Health Organization reevaluated the toxic equivalency factors (TEFs) for chlorinated dioxin-like compounds in a panel convened in Lisbon. This effort utilized an updated database, Bayesian dose response modeling, and meta-analysis to derive Best-Estimate TEFs. Applying these new TEFs may result in lower total toxic equivalents for dioxin-like chemicals.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)
