Article
Anesthesiology
Nicole Ortiz, Leili Shahgholi, Lynn Kohan, Sayed E. Wahezi
Summary: Lidocaine and contrast agents have an impact on lesion characteristics during monopolar radiofrequency ablation (RFA).
Article
Cardiac & Cardiovascular Systems
Hiroshi Nakagawa, Atsushi Ikeda, Tushar Sharma, Assaf Govari, John Ashton, Jennifer Maffre, Alexander Lifshitz, Kristine Fuimaono, Katsuaki Yokoyama, Fred H. M. Wittkampf, Warren M. Jackman
Summary: This study compared tissue temperature profiles, lesion sizes, and complications between different RF ablation parameters. The results showed that RF ablation with very high power and short duration (90W/4s) resulted in the smallest tissue temperatures and lesion sizes, while ablation with moderate power and longer duration (30W/30s) led to the largest outcomes. Additionally, RF applications at 90W/4s exhibited a longer thermal latency, indicating a significant portion of the lesion was created after RF termination.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Qian Wang, Bingyu Huang, Shengqi Huo, Junyi Guo, Haojie Li, Tao Jiang, Dewei Peng, Lintong Men, Dazhong Tang, Chunlin Xiang, Yi Luo, Xiu Pi, Lulu Peng, Yue Jiang, Mengying Zhu, Wei Shi, Sheng Li, Jiagao Lv, Li Lin
Summary: This study quantitatively analyzed the relationship between ablation parameters and tissue lesion following pulmonary vein isolation (PVI) at different segments of pulmonary vein (PV) using LGE-CMR. The results showed that tissue lesion on the posterior wall of PV was more severe than on the non-posterior wall when similar ablation parameters were applied. LSI was a better index to reflect tissue lesion quality at the non-posterior wall of PV.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Multidisciplinary Sciences
Soo Young Park, Rajinder Singh-Moon, Haiqiu Yang, Deepak Saluja, Christine Hendon
Summary: This study evaluated the use of NIRS-integrated RFA catheters for monitoring lesion progression, both ex vivo and in vivo. The results showed that the predictive model based on spectral features correlated well with measured lesion dimensions, and the in vivo pilot studies demonstrated consistent contact discrimination and accurate lesion depth parameters. NIRS-empowered catheters are well suited for monitoring myocardial response to RF ablation and optimizing treatment efficacy.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Lijuan Qu, Min Guo, Meng Sun, Rui Wang, Nan Zhang, Xin Li
Summary: This study aimed to investigate the effects of baseline impedance and power on radiofrequency ablation lesion characteristics and their correlation with steam pops. The results showed a strong correlation between lesion characteristics and ablation index and baseline impedance. The occurrence rate of steam pops was higher under high power and high impedance conditions.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Luisana Di Cristo, Johannes G. Keller, Luca Leoncino, Valentina Marassi, Frederic Loosli, Didem Ag Seleci, Georgia Tsiliki, Agnes G. Oomen, Vicki Stone, Wendel Wohlleben, Stefania Sabella
Summary: This article investigates the effects of different digestive juice formulations on the dissolution rate of nanomaterials and evaluates the advantages and disadvantages of different formulations. The results indicate that the Type 1 formulation, which includes enzymes, has a significant impact on the dissolution of nanomaterials and is therefore considered a preferable method for predicting biodurability. Furthermore, the use of simplified formulations for grouping purposes has also been shown to be a robust screening method.
NANOSCALE ADVANCES
(2023)
Article
Cardiac & Cardiovascular Systems
Felix Bourier, Miruna Popa, Marc Kottmaier, Susanne Maurer, Fabian Bahlke, Marta Telishevska, Sarah Lengauer, Katharina Koch-Buettner, Marielouise Kornmayer, Elena Risse, Amir Brkic, Tilko Reents, Gabriele Hessling, Isabel Deisenhofer
Summary: The study found that the coverage between the RF electrode and cardiac tissue significantly influenced the incidence of steam pops and lesion size, with larger coverage resulting in larger lesions.
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Yuxia Miao, Min Xu, Ling Yang, Chunxu Zhang, Huannian Liu, Xiaoliang Shao
Summary: This study found a linear and positive association between P wave duration within 72 hours after radiofrequency ablation and the risk of atrial fibrillation recurrence in patients with early persistent atrial fibrillation. This association was consistent across different subgroups and there was no significant interaction.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Chi Cai, Jing Wang, Hong-Xia Niu, Jian-Min Chu, Wei Hua, Shu Zhang, Yan Yao
Summary: This study investigates the association between lesion size index (LSI) and acute conduction gap formation during high-power (HP) ablation for pulmonary vein isolation (PVI) in atrial fibrillation (AF) patients. Using LSI-guided HP ablation, a LSI value above 4.35 for all PV segments showed the best predictive value in avoiding gap formation for effective first-pass PVI. The optimal LSI cutoff values for predicting gap formation were 4.55 for the anterior wall and 3.95 for the posterior wall.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Wataru Sasaki, Kazuhisa Matsumoto, Syunta Higuchi, Hitoshi Mori, Hidehira Fukaya, Daisuke Kawano, Naomichi Tanaka, Masataka Narita, Kenta Tsutsui, Yoshifumi Ikeda, Takahide Arai, Shintaro Nakano, Ritsushi Kato
Summary: This study performed a cross-sectional and longitudinal analysis of DT catheters in an excised swine heart model, finding that the ablation depth, diameter, and volume were significantly lower with a 10 g catheter compared to a 30 g or 50 g catheter. There were no significant differences in lesion formation between 30 g and 50 g catheters under the same RF power setting. The impedance drops with steam pops were significantly greater than those without steam pops.
JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Fabian Bahlke, Andreas Wachter, Nico Erhard, Florian Englert, Hannah Krafft, Miruna Popa, Elena Risse, Marc Kottmaier, Marta Telishevska, Sarah Lengauer, Carsten Lennerz, Tilko Reents, Gabriele Hessling, Isabel Deisenhofer, Felix Bourier
Summary: This study investigates the effects of local impedance and electrode-tissue-coverage on lesion formation using an ex vivo model. The results show that electrode-tissue-coverage is a major determinant of lesion size and occurrence of steam pops.
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Management
Zhenyu Hu, Wenjie Tang
Summary: This paper explores the interaction between offer size and offer deadline in a Stackelberg game, taking into account the responder's reaction and the impact of market conditions on the proposer's optimal strategy. The proposer should offer an exploding offer in an unfavorable market, and a smaller nonexploding offer in a favorable market, with the deadline varying accordingly.
MANAGEMENT SCIENCE
(2021)
Article
Biochemical Research Methods
Saud Alguwaizani, Shulei Ren, De-Shuang Huang, Kyungsook Han
Summary: Our study identified a linear relationship between amino acid composition and sequence length in proteins involved in PPIs between humans and bacteria, leading to the development of a support vector machine model that showed high performance in predicting PPIs. The model also demonstrated good performance in predicting PPIs between humans and viruses such as Ebola, HCV, and SARS-CoV-2, highlighting the potential for further research and application in identifying unknown target host proteins and designing experiments.
CURRENT BIOINFORMATICS
(2021)
Article
Materials Science, Multidisciplinary
R. C. Bell, N. M. Wereley
Summary: The yield stress of magnetorheological fluids is influenced by particle morphology, and this study investigates the rheological properties of cobalt nanowire suspensions with varying aspect ratios. The results show that the yield stress increases linearly with aspect ratio and reaches a plateau.
INTERNATIONAL JOURNAL OF SMART AND NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Xuri Wu, Feng Tan, Shizhu Cheng, Yangyang Chang, Xiaochun Wang, Lingxin Chen
Summary: In this study, three types of MXene Ti3C2Tx nanosheets were prepared using different etching methods, and their behavior after exposure to human plasma was investigated. The study found that nanosheets with protein coronas were more prone to aggregation, and proteomic analysis revealed significant differences in the composition and abundance of proteins in the coronas. A random forest classification model identified hydrogen bonding, steric hindrance, and hydrophobic interaction as the main driving forces for the adsorption of plasma proteins on Ti3C2Tx.