Journal
REACTIVE & FUNCTIONAL POLYMERS
Volume 91-92, Issue -, Pages 35-42Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.reactfunctpolym.2015.04.001
Keywords
Aza-Michael addition reaction; Amino acid containing polymer; (Meth)acrylate and acxylamide monomers; Reactivity of alpha, beta unsaturated carbonyls; Functional polymer
Funding
- Department of Science and Technology (DST), New Delhi, India [SR/S1/OC-51/2010]
- DST
- Council of Scientific and Industrial Research (CSIR), Government of India
Ask authors/readers for more resources
An efficacious protocol for the aza-Michael addition of a C-terminus modified phenylalanine side-chain containing polymer (Michael donor) was demonstrated with various Michael acceptors. The aza-Michael addition reactions were carried out at 50 degrees C in anhydrous methanol, which is a protic solvent, to enhance the advancement of the reactions. H-1 and inverse gated C-13 NMR spectroscopy were utilized to qualitatively deliver comprehensive data on the reaction progress. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF) provided quantitative information about the modification of the polymer. The extent of change in the aza-Michael addition varied with different Michael acceptors and decreased in the order of acrylate > acrylamide > methacrylate. The present study opens up a library of polymers with functional modifications in the side-chain. (C) 2015 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available