Article
Biochemical Research Methods
Xiaoya Fu, Xia Wang, Zhining Xia, Yike Huang
Summary: In this study, a sample pretreatment method for genotoxic impurities (GTIs) with very trace content in medicine was established using dummy template molecular imprinting technology (DMIT) and solid phase extraction. The optimal adsorption conditions were obtained through conditional optimization, and the quality control of GTIs in pharmaceuticals was achieved.
JOURNAL OF CHROMATOGRAPHY A
(2022)
Review
Polymer Science
Marisa Dwi Ariani, Ade Zuhrotun, Panagiotis Manesiotis, Aliya Nur Hasanah
Summary: Molecular imprinting technology has the potential to effectively separate and purify target compounds. The use of dummy template in molecularly imprinted polymers provides a solution for the unavailability of target compounds and template leakage. This technique is especially useful for removing allergenic or toxic compounds from natural product samples.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Chemistry, Analytical
Arash Mohammadinejad, Seyedeh Zohreh Kamrani Rad, Gholamreza Karimi, Vahideh Sadat Motamedshariaty, Seyed Ahmad Mohajeri
Summary: This study aimed to develop a selective solid phase extraction method using dummy molecularly imprinting approach for extraction and clean-up of hesperidin in lime juice, in order to check the quality of commercial lime juice products. The synthesized molecularly imprinted polymer showed high adsorption capacity for hesperidin and successfully removed interfering compounds for accurate analysis. The analysis of hesperidin in lime juice was done by high-performance liquid chromatography, with a detection limit of 0.05 µg/mL.
JOURNAL OF SEPARATION SCIENCE
(2021)
Article
Engineering, Chemical
Chunyan Hu, Jianyi Li, Juncheng Ke, Jianjun Liang, Qiuliang Liu, Qiliang Wang, Wentao Huang
Summary: Double template magnetic molecularly imprinted polymers (CBZ/OXC-MIPs) were successfully prepared with specific recognition for carbamazepine (CBZ) and oxcarbazepine (OXC). The preparation process was optimized for the ratio of template molecules to functional monomer, crosslinker and solvent dosages, and the ratio of CBZ to OXC. The adsorption experiments showed that CBZ/OXC-MIPs exhibited specific recognition and the adsorption process followed the Freundlich model and pseudo-second-order kinetic model. The selective adsorption of CBZ/OXC-MIPs was mainly attributed to van der Waals forces, hydrogen bond, and electrostatic interaction.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Polymer Science
Ouahiba Beladghame, Nouria Bouchikhi, Djahida Lerari, Imad Eddine Charif, Olivier Soppera, Ulrich Maschke, Lamia Bedjaoui-Alachaher
Summary: This study developed novel molecularly imprinted polymers (MIPs) films using a non-covalent approach for the herbicide 2,4-D using phenoxypropionic acid (PPA) as an analogue. MIPs were prepared through photo-polymerization with specific monomers, cross-linkers, templates, initiators, and solvents. Characterization techniques such as IR, TGA, and AFM were used to evaluate the properties of MIPs. Gas chromatography (GC) was used to compare the recognition abilities of MIPs and non-imprinted polymers (NIPs). Factors such as film mass, template concentration, and cross-linking density were varied to optimize the binding characteristics of MIPs.
IRANIAN POLYMER JOURNAL
(2023)
Article
Biochemical Research Methods
Zilong Chen, Hongdong Liu, Jie Chen, Weifeng Zhu, Yong Liu, Jianxin Min, Xiaotian Chen, Bin Li, Xin Yang
Summary: In this study, a novel strategy utilizing dummy molecular imprinting technology and magnetic separation technology was developed for the separation and enrichment of sibiskoside. The prepared dummy template molecularly imprinted polymers (DMIPs) demonstrated high adsorption capacity for sibiskoside and good reusability. The purity of sibiskoside in crude extracts was increased to 78%, providing a foundation for the further development and utilization of Sibiraea angustata and the separation and enrichment of monoterpenes.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Chemistry, Analytical
Amineh Sadat Tajani, Vahid Soheili, Fatemeh Moosavi, Razieh Ghodsi, Taher Alizadeh, Bibi Sedigheh Fazly Bazzaz
Summary: A highly selective molecular imprinting polymer was developed to attenuate biofilm formation of the multidrug-resistant pathogen Pseudomonas aeruginosa by disrupting the intermolecular signaling system. The results showed a significant difference in biofilm inhibition between the imprinted and non-imprinted polymer, indicating the potential of the molecular imprinting polymer in clinical and industrial applications.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biochemical Research Methods
Pengqi Guo, Chenming Liu, Fanru Zhong, Mingyang Xu, Yongze Zhao, Xinya Xu, Yu Zhao, Weiming Xue, Ying Xu, Daidi Fan
Summary: In this study, dummy-template molecularly imprinted polymers were prepared and characterized, and an online solid phase extraction-high performance liquid chromatography (SPE-HPLC) analytical system was established for the simultaneous determination of four estrogens in cosmetic samples. The method showed high accuracy, precision, and sensitivity, and was suitable for complex samples analysis.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Polymer Science
Tjasa Gornik, Sudhirkumar Shinde, Lea Lamovsek, Maja Koblar, Ester Heath, Borje Sellergren, Tina Kosjek
Summary: This study demonstrated the potential of molecularly imprinted polymers as sorbents for removing SSRIs in water treatment, with optimized composition to achieve highest capacity, affinity, and selectivity. The MIPs showed stable performance, reusability, and superior sorption capabilities in wastewaters, making them better suited for use in wastewater treatment.
Article
Chemistry, Analytical
Yibin Liu, Huaisyuan Xie, Xinyi Li, Ying Sun, Zhiwei Zhu, Meiping Zhao
Summary: A method for online monitoring of dopamine-based molecular imprinting processes using a real-time quantitative PCR machine is reported. The method allows precise control of different proteins and enables quantitative isolation of target proteins from cell lysate samples.
Article
Food Science & Technology
Zhenke Qi, Cheng Xiang, Xingguo Tian, Xiaoyan Xu
Summary: This study describes the development of a dual-emitting, molecularly imprinted, ratiometric fluorescence sensor for the rapid detection of Ciguatoxin P-CTX-3C. The sensor showed high sensitivity and selectivity, and was able to detect the toxin in coral reef fish samples.
Article
Engineering, Environmental
Shufang Xu, Xiaolan Zhang, Zhigang Xu, Yunli Duan, Zhimin Liu, Yan Zhang
Summary: A three-template MIP solid-phase microextraction fiber array technique with improved adsorption flux and extraction capacity was developed and utilized for screening phthalates in environmental water. The study showed that this technique has great potential for monitoring and controlling phthalate in environmental water.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
Review
Chemistry, Medicinal
Luxuan Zhang, Hua Yu, Haifang Chen, Yinghong Huang, Irina Bakunina, Damia Pregentino de Sousa, Mingna Sun, Jianye Zhang
Summary: The molecular imprinting technique is an attractive and prominent method for synthesizing materials used for target recognition and rapid separation. It has been successfully applied in the separation of active compounds from various plants, such as flavonoids, organic acids, alkaloids, phenylpropanoids, anthraquinones, phenolics, terpenes, steroids, and diketones. This review provides a brief introduction of molecularly imprinted polymers and their efficient application in the separation of active components from plants, offering valuable insights for stimulating further research in this fascinating and useful field.
Article
Chemistry, Physical
Xiaoxiao Zhao, Daniel S. Park, Junseo Choi, Sungook Park, Steven A. Soper, Michael C. Murphy
Summary: Utilizing a flexible nylon mesh template, re-entrant structures can be easily imprinted in one step without damage. Pre-coated silica nanoparticles and epoxy resin not only improve liquid repellency by introducing hierarchical surface structures, but also act as a protective layer against mechanical abrasion.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Applied
Nilawan Surapong, Prachathipat Pongpinyo, Yanawath Santaladchaiyakit, Rodjana Burakham
Summary: An eco-friendly magnetic dual-dummy-template molecularly imprinted polymer (MDDMIP) was synthesized using mixed-valence iron hydroxide, a deep eutectic solvent, and caffeic acid and glutamic acid as binary monomers. The MDDMIP exhibited high adsorption capacities, quick adsorption times, and high imprinting factors for organophosphorus pesticides (OPPs). The MDDMIP was utilized for magnetic solid phase extraction combined with high performance liquid chromatography (HPLC) to detect OPPs in food samples.
Article
Agricultural Engineering
M. Soto, M. A. Vazquez, A. de Vega, J. M. Vilarino, G. Fernandez, M. E. S. de Vicente
BIORESOURCE TECHNOLOGY
(2015)
Article
Food Science & Technology
Rafaela Teixeira, Sonia Dopico-Garcia, Paula B. Andrade, Patricia Valentao, Jose M. Lopez-Vilarino, Victoria Gonzalez-Rodriguez, Concepcion Cela-Perez, Luis R. Silva
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2015)
Article
Chemistry, Analytical
M. C. Cela-Perez, L. Barbosa-Pereira, X. Vecino, M. Perez-Ameneiro, Aurora Lasagabaster Latorre, J. M. Lopez-Vilarino, M. V. Gonzalez Rodriguez, A. B. Moldes, J. M. Cruz
Article
Chemistry, Applied
Marta Lopez-Garcia, Maria Sonia Dopico Garcia, Jose Manuel Lopez Vilarino, Maria Victoria Gonzalez Rodriguez
Article
Biochemical Research Methods
M. Concepcion Cela-Perez, Ferdia Bates, Cristian Jimenez-Morigosa, Elena Lendoiro, Ana de Castro, Angelines Cruz, Manuel Lopez-Rivadulla, Jose M. Lopez-Vilarino, M. Victoria Gonzalez-Rodriguez
JOURNAL OF CHROMATOGRAPHY A
(2016)
Article
Food Science & Technology
A. V. Rodriguez-Martinez, R. Sendon, M. J. Abad, M. V. Gonzalez-Rodriguez, J. Barros-Velazquez, S. P. Aubourg, P. Paseiro-Losada, A. Rodriguez-Bernaldo de Quiros
LWT-FOOD SCIENCE AND TECHNOLOGY
(2016)
Article
Polymer Science
Rebeca Bouza, Maria del Mar Castro, Sonia Dopico-Garcia, M. Victoria Gonzalez-Rodriguez, Luis F. Barral, Birgit Bittmann
Article
Materials Science, Multidisciplinary
Laura Horta-Romaris, Maria-Jose Abad, M. Victoria Gonzalez-Rodriguez, Aurora Lasagabaster, Pedro Costa, Senentxu Lanceros-Mendez
MATERIALS & DESIGN
(2017)
Article
Materials Science, Multidisciplinary
Laura Horta-Romaris, M. Victoria Gonzalez-Rodriguez, Aurora Lasagabaster, Francisco Rivadulla, Maria-Jose Abad
Article
Biochemical Research Methods
M. Paredes-Ramos, A. Sabin-Lopez, J. Pena-Garcia, H. Perez-Sanchez, J. M. Lopez-Vilarino, M. E. Sastre de Vicente
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
(2020)
Article
Food Science & Technology
Maria Paredes-Ramos, Enma Conde Pineiro, Horacio Perez-Sanchez, Jose M. Lopez-Vilarino
Summary: In a preventive context, natural peptides, such as SDRFSY, LSDRFS, and VIKP, have been found to play a significant role in combating SARS-CoV-2 by blocking ACE2 and CD26 or reducing inflammation associated with COVID-19.
JOURNAL OF FOOD QUALITY
(2022)
Article
Chemistry, Applied
Xiaodan Wu, Zihan Wang, Guansong Shao, Bingyang Qin, Ying Wang, Tao Wang, Zhiguo Liu, Yujie Fu
Summary: In this study, a new type of cellulose-based ionic imprinting adsorbent was developed for the selective removal of cobalt ions. The adsorbent exhibited excellent adsorption performance, high cycling stability, and preferential selectivity for cobalt ions. The simple preparation method and promising application prospects make it a promising candidate for water treatment.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Article
Chemistry, Applied
Chandirasekar Shanmugam, Vanitha Marimuthu, Nagappan Rajendiran
Summary: In this study, monodispersed gold and silver nanoparticles were synthesized using cholic acid functionalized star poly(DL-lactide) as a capping and reducing agent. The synthesized materials were found to be effective heterogeneous catalysts for the reduction reaction.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Article
Chemistry, Applied
Bianca-Iulia Ciubotaru, Mirela-Fernanda Zaltariov, Mihaela Dascalu, Adrian Bele, Alexandra Bargan, Maria Cazacu
Summary: Porous networks were obtained using polysiloxanes pendant functionalized with aminopropyl groups. The addition of certain substances, such as ammonium bicarbonate and acetic acid, promoted the porosity and covalent cross-linking of the polymer. The resulting materials exhibited high dielectric permittivity and significant electrical output signal when subjected to compression, making them suitable for capacitive pressure sensors.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Article
Chemistry, Applied
Mohamed A. Zein, Basim H. Asghar, Abdulaziz M. Almohyawi, Norah F. Alqahtani, Ahmed Alharbi, J. Alkabli, Reda F. M. Elshaarawy, Lamia A. Ismail
Summary: In this study, new amphiphilic chitosan-thyme extract-nanosilver nanocomposites were prepared, which synergistically inhibited bacterial biofilm formation and bacterial proliferation. The nanocomposites disrupted bacterial cell membranes, causing cell death, and prevented biofilm formation. In addition, the nanocomposites exhibited good biocompatibility, making them potential candidates for biomedical applications.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Review
Chemistry, Applied
Norah F. Alqahtani
Summary: This review explores the potential of Imidazolium-based ionic liquids (ImILs) in improving the solubility, stability, and functionality of chitosan, and provides an overview of the types and preparation methods of functionalized imidazolium ionic liquids (FImILs). Additionally, it discusses the various opportunities offered by FImIL-chitosan derivatives.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Article
Chemistry, Applied
Olesya N. Zabegaeva, Alexey F. Kosolapov, Sergei L. Semjonov, Mariam G. Ezernitskaya, Egor S. Afanasyev, Ivan A. Godovikov, Alexander Chuchalov, Dmitriy A. Sapozhnikov
Summary: Polyimides are commonly used as primary protective coatings for optical fibers in high-temperature applications. However, the manufacturing process is complicated due to certain drawbacks. This study shows the potential use of polyamide-imides as highly reliable protective coatings for optical fibers.
REACTIVE & FUNCTIONAL POLYMERS
(2024)
Article
Chemistry, Applied
Luis Miguel Nunez Tapia, Pascal Thebault, Laurent Bischoff, Alain Ledoux, Florian Defontaine, Olivier Lesouhaitier, Fabrice Burel
Summary: A water soluble cationic bis-cyclocarbonate was prepared through a three steps procedure, and non-isocyanate polyurethanes were prepared in acetonitrile with high yields. The resulting materials exhibited good thermal properties and hydrophilic properties. The polyurethane thermoset showed high inhibition towards bacteria, and the bis-cyclocarbonate oligomer was found to be harmless to organisms.
REACTIVE & FUNCTIONAL POLYMERS
(2024)