Fine-Tuning of Charge-Conversion Polymer Structure for Efficient Endosomal Escape of siRNA-Loaded Calcium Phosphate Hybrid Micelles

Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles

(2014) Frederico Pittella et al.   JOURNAL OF CONTROLLED RELEASE

Mechanism of Polyplex- and Lipoplex-Mediated Delivery of Nucleic Acids: Real-Time Visualization of Transient Membrane Destabilization without Endosomal Lysis

(2013) Zia ur Rehman et al.   ACS Nano

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles

(2012) Frederico Pittella et al.   JOURNAL OF CONTROLLED RELEASE

Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise

(2011) Ernst Wagner   ACCOUNTS OF CHEMICAL RESEARCH

Multimodal Analysis of PEI-Mediated Endocytosis of Nanoparticles in Neural Cells

(2011) Cameron W. Evans et al.   ACS Nano

Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides

(2011) Rudolph L. Juliano et al.   BIOCONJUGATE CHEMISTRY

Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity

(2011) Frederico Pittella et al.   BIOMATERIALS

Rational design of smart supramolecular assemblies for gene delivery: chemical challenges in the creation of artificial viruses

(2011) Kanjiro Miyata et al.   CHEMICAL SOCIETY REVIEWS

Odd–Even Effect of Repeating Aminoethylene Units in the Side Chain of N-Substituted Polyaspartamides on Gene Transfection Profiles

(2011) Hirokuni Uchida et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Interaction of Poly(ethylenimine)–DNA Polyplexes with Mitochondria: Implications for a Mechanism of Cytotoxicity

(2011) Giovanna Grandinetti et al.   MOLECULAR PHARMACEUTICS

Calcium phosphate-based composite nanoparticles in bioimaging and therapeutic delivery applications

(2011) Amra Tabaković et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy

(2009) Kevin Buyens et al.   JOURNAL OF CONTROLLED RELEASE

Charge‐Conversion Ternary Polyplex with Endosome Disruption Moiety: A Technique for Efficient and Safe Gene Delivery

(2008) Yan Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polyplexes from Poly(aspartamide) Bearing 1,2-Diaminoethane Side Chains Induce pH-Selective, Endosomal Membrane Destabilization with Amplified Transfection and Negligible Cytotoxicity

(2008) Kanjiro Miyata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY