Polymeric Biomaterials for Stem Cell Bioengineering

Using Mean Field Theory to Guide Biofunctional Materials Design

(2012) Uwe Freudenberg et al.   ADVANCED FUNCTIONAL MATERIALS

Sustained delivery of SDF-1α from heparin-based hydrogels to attract circulating pro-angiogenic cells

(2012) Silvana Prokoph et al.   BIOMATERIALS

The location and cellular composition of the hemopoietic stem cell niche

(2012) Sarah L. Ellis et al.   CYTOTHERAPY

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

Human Mesenchymal Stem Cell-Derived Matrices for Enhanced Osteoregeneration

(2012) S. Zeitouni et al.   Science Translational Medicine

Photoreversible Patterning of Biomolecules within Click-Based Hydrogels

(2011) Cole A. DeForest et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Orientation-regulated immobilization of Jagged1 on glass substrates for ex vivo proliferation of a bone marrow cell population containing hematopoietic stem cells

(2011) Hiroyuki Toda et al.   BIOMATERIALS

Delivery of Oct4 and SirT1 with cationic polyurethanes-short branch PEI to aged retinal pigment epithelium

(2011) Chi-Hsien Peng et al.   BIOMATERIALS

Enhanced proliferation of neural stem cells in a collagen hydrogel incorporating engineered epidermal growth factor

(2011) Edgar Y. Egawa et al.   BIOMATERIALS

Cultured cell-derived extracellular matrix scaffolds for tissue engineering

(2011) Hongxu Lu et al.   BIOMATERIALS

Systematic engineering of 3D pluripotent stem cell niches to guide blood development

(2011) Kelly A. Purpura et al.   BIOMATERIALS

Ex vivo expansion of human hematopoietic stem and progenitor cells

(2011) A. Dahlberg et al.   BLOOD

Towards a quantitative understanding of stem cell–niche interaction: Experiments, models, and technologies

(2011) Ingo Roeder et al.   BLOOD CELLS MOLECULES AND DISEASES

Biomaterials meet microfluidics: building the next generation of artificial niches

(2011) Stefan Kobel et al.   CURRENT OPINION IN BIOTECHNOLOGY

On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup

(2011) Nico Scherf et al.   EXPERIMENTAL HEMATOLOGY

Rescuing replication and osteogenesis of aged mesenchymal stem cells by exposure to a young extracellular matrix

(2011) Yun Sun et al.   FASEB JOURNAL

Mesenchymal stem cells and bone regeneration: Current status

(2011) Elena Jones et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells

(2011) Barbara Varnum-Finney et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular Matrix Functionalized Microcavities to Control Hematopoietic Stem and Progenitor Cell Fate

(2011) Ina Kurth et al.   MACROMOLECULAR BIOSCIENCE

Swelling Equilibrium of a Binary Polymer Gel

(2011) Jens-Uwe Sommer et al.   MACROMOLECULES

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency

(2011) Rebecca J. McMurray et al.   NATURE MATERIALS

Three-dimensional biomaterials for the study of human pluripotent stem cells

(2011) Thomas P Kraehenbuehl et al.   NATURE METHODS

Chemically defined conditions for human iPSC derivation and culture

(2011) Guokai Chen et al.   NATURE METHODS

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

(2011) Justin R. Tse et al.   PLoS One

Surface-engineered substrates for improved human pluripotent stem cell culture under fully defined conditions

(2011) K. Saha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells

(2011) Hideaki Tsutsui et al.   Nature Communications

A Comprehensive Model of the Spatio-Temporal Stem Cell and Tissue Organisation in the Intestinal Crypt

(2011) Peter Buske et al.   PLoS Computational Biology

Bioinspired Materials for Controlling Stem Cell Fate

(2010) Omar Z. Fisher et al.   ACCOUNTS OF CHEMICAL RESEARCH

Neural stem cell adhesion and proliferation on phospholipid bilayers functionalized with RGD peptides

(2010) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells

(2010) Shawn H. Lim et al.   BIOMATERIALS

Toward modeling the bone marrow niche using scaffold-based 3D culture systems

(2010) Nunzia Di Maggio et al.   BIOMATERIALS

High-throughput methods to define complex stem cell niches

(2010) Stefan Kobel et al.   BIOTECHNIQUES

Adipose Stem Cells for Soft Tissue Regeneration

(2010) C. Brayfield et al.   Handchirurgie Mikrochirurgie Plastische Chirurgie

Enabling stem cell therapies through synthetic stem cell–niche engineering

(2010) Raheem Peerani et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic interaction networks in a hierarchically organized tissue

(2010) Daniel C Kirouac et al.   Molecular Systems Biology

Synthetic polymer coatings for long-term growth of human embryonic stem cells

(2010) Luis G Villa-Diaz et al.   NATURE BIOTECHNOLOGY

Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells

(2010) Jeff Holst et al.   NATURE BIOTECHNOLOGY

Synthetic peptide-acrylate surfaces for long-term self-renewal and cardiomyocyte differentiation of human embryonic stem cells

(2010) Zara Melkoumian et al.   NATURE BIOTECHNOLOGY

Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511

(2010) Sergey Rodin et al.   NATURE BIOTECHNOLOGY

Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

(2010) John T. Connelly et al.   NATURE CELL BIOLOGY

Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells

(2010) Ying Mei et al.   NATURE MATERIALS

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

A defined glycosaminoglycan-binding substratum for human pluripotent stem cells

(2010) Joseph R Klim et al.   NATURE METHODS

Nanotechnological strategies for engineering complex tissues

(2010) Tal Dvir et al.   Nature Nanotechnology

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Tissue-Engineered Three-Dimensional Tumor Models to Study Tumor Angiogenesis

(2010) Scott S. Verbridge et al.   TISSUE ENGINEERING PART A

Can tissue engineering concepts advance tumor biology research?

(2010) Dietmar W. Hutmacher et al.   TRENDS IN BIOTECHNOLOGY

Human mesenchymal stem cell differentiation on self-assembled monolayers presenting different surface chemistries

(2009) Jennifer E. Phillips et al.   Acta Biomaterialia

Artificial Stem Cell Niches

(2009) Matthias P. Lutolf et al.   ADVANCED MATERIALS

A star-PEG–heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases

(2009) Uwe Freudenberg et al.   BIOMATERIALS

Engineering integrin signaling for promoting embryonic stem cell self-renewal in a precisely defined niche

(2009) Seung Tae Lee et al.   BIOMATERIALS

Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix

(2009) Farshid Guilak et al.   Cell Stem Cell

Hematopoietic stem and progenitor cells in adhesive microcavities

(2009) Ina Kurth et al.   Integrative Biology

Designing materials to direct stem-cell fate

(2009) Matthias P. Lutolf et al.   NATURE

Complexity in biomaterials for tissue engineering

(2009) Elsie S. Place et al.   NATURE MATERIALS

Biomaterials for promoting brain protection, repair and regeneration

(2009) Gorka Orive et al.   NATURE REVIEWS NEUROSCIENCE

Estimating Dormant and Active Hematopoietic Stem Cell Kinetics through Extensive Modeling of Bromodeoxyuridine Label-Retaining Cell Dynamics

(2009) Richard C. van der Wath et al.   PLoS One

Stem cell fate dictated solely by altered nanotube dimension

(2009) S. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Reconstitution of Marrow-Derived Extracellular Matrix Ex Vivo: A Robust Culture System for Expanding Large-Scale Highly Functional Human Mesenchymal Stem Cells

(2009) Yanlai Lai et al.   STEM CELLS AND DEVELOPMENT

Engineered Extracellular Matrices Modulate the Expression Profile and Feeder Properties of Bone Marrow-Derived Human Multipotent Mesenchymal Stromal Cells

(2009) F. Philipp Seib et al.   TISSUE ENGINEERING PART A

Neural Stem Cell– and Schwann Cell–Loaded Biodegradable Polymer Scaffolds Support Axonal Regeneration in the Transected Spinal Cord

(2009) Heather E. Olson et al.   TISSUE ENGINEERING PART A

Directed Growth of Adult Human White Matter Stem Cell–Derived Neurons on Aligned Fibrillar Collagen

(2009) Babette Lanfer et al.   TISSUE ENGINEERING PART A

Stem Cell Proliferation and Quiescence—Two Sides of the Same Coin

(2009) Ingmar Glauche et al.   PLoS Computational Biology

Aligned fibrillar collagen matrices obtained by shear flow deposition

(2008) Babette Lanfer et al.   BIOMATERIALS

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

The Case for a Metabolic Stem Cell Niche

(2008) Michael Cross et al.   CELLS TISSUES ORGANS

Perturbation of single hematopoietic stem cell fates in artificial niches

(2008) Matthias P. Lutolf et al.   Integrative Biology

Clinical transplantation of a tissue-engineered airway

(2008) Paolo Macchiarini et al.   LANCET

Small functional groups for controlled differentiation of hydrogel-encapsulated human mesenchymal stem cells

(2008) Danielle S. W. Benoit et al.   NATURE MATERIALS

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

(2008) Harald C Ott et al.   NATURE MEDICINE

Functional immobilization of signaling proteins enables control of stem cell fate

(2008) Kristin Alberti et al.   NATURE METHODS

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recombinant Vitronectin Is a Functionally Defined Substrate That Supports Human Embryonic Stem Cell Self-Renewal via αVβ5 Integrin

(2008) Stefan R. Braam et al.   STEM CELLS

Laminin-511 but Not -332, -111, or -411 Enables Mouse Embryonic Stem Cell Self-Renewal In Vitro

(2008) Anna Domogatskaya et al.   STEM CELLS

Controlled differentiation of stem cells

(2007) Nathaniel S. Hwang et al.   ADVANCED DRUG DELIVERY REVIEWS

Distinct Effects of the Soluble Versus Membrane-Bound Forms of the Notch Ligand Delta-4 on Human CD34+CD38lowCell Expansion and Differentiation

(2007) Medhi Lahmar et al.   STEM CELLS