RAFT Polymerization and Thiol Chemistry: A Complementary Pairing for Implementing Modern Macromolecular Design

Emerging synthetic approaches for protein–polymer conjugations

(2011) Rebecca M. Broyer et al.   CHEMICAL COMMUNICATIONS

The use of reversible addition fragmentation chain transfer polymerization for drug delivery systems

(2011) Andrew Gregory et al.   Expert Opinion on Drug Delivery

Conjugation of siRNA with Comb-Type PEG Enhances Serum Stability and Gene Silencing Efficiency

(2011) Karthikeyan Gunasekaran et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Reversible and Multisensitive Quantum Dot Gels

(2011) Jun-Jie Yan et al.   MACROMOLECULES

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Solution-state Assembly or Bulk State Thiol-ene Crosslinking of Pyrrolidinone- and Alkene-functionalized Amphiphilic Block Fluorocopolymers: From Functional Nanoparticles to Anti-fouling Coatings

(2010) Jun Ma et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Intracellular Delivery of a Protein Antigen with an Endosomal-Releasing Polymer Enhances CD8 T-Cell Production and Prophylactic Vaccine Efficacy

(2010) Suzanne Foster et al.   BIOCONJUGATE CHEMISTRY

Rational Design of Targeted Cancer Therapeutics through the Multiconjugation of Folate and Cleavable siRNA to RAFT-Synthesized (HPMA-s-APMA) Copolymers†

(2010) Adam W. York et al.   BIOMACROMOLECULES

Double Thermoresponsive Block Copolymers Featuring a Biotin End Group

(2010) Florian D. Jochum et al.   BIOMACROMOLECULES

Shell-Sheddable Micelles Based on Dextran-SS-Poly(ε-caprolactone) Diblock Copolymer for Efficient Intracellular Release of Doxorubicin

(2010) Huanli Sun et al.   BIOMACROMOLECULES

Backbone Degradable MultiblockN-(2-Hydroxypropyl)methacrylamide Copolymer Conjugates via Reversible Addition−Fragmentation Chain Transfer Polymerization and Thiol−ene Coupling Reaction

(2010) Huaizhong Pan et al.   BIOMACROMOLECULES

Functional, star polymeric molecular carriers, built from biodegradable microgel/nanogel cores

(2010) Jay A. Syrett et al.   CHEMICAL COMMUNICATIONS

Post-functionalization of ATRPpolymers using both thiol/ene and thiol/disulfide exchange chemistry

(2010) Cyrille Boyer et al.   CHEMICAL COMMUNICATIONS

Thiol-click chemistry: a multifaceted toolbox for small molecule and polymer synthesis

(2010) Charles E. Hoyle et al.   CHEMICAL SOCIETY REVIEWS

Protein–polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications

(2010) Gregory N Grover et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Block copolymers via macromercaptan initiated ring opening polymerization

(2010) Catherine Lefay et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Reducibly degradable hydrogels of PNIPAM and PDMAEMA: Synthesis, stimulus-response and drug release

(2010) Bo-yu Zhang et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

A simple methodology for the synthesis of heterotelechelic protein-polymer-biomolecule conjugates

(2010) Jingquan Liu et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Building nanostructures using RAFT polymerization

(2010) Cyrille Boyer et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Limitations of radical thiol-ene reactions for polymer-polymer conjugation

(2010) Sandy P. S. Koo et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

The power of thiol-ene chemistry

(2010) Matthew J. Kade et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Surface-Functionalizable Polymer Nanogels with Facile Hydrophobic Guest Encapsulation Capabilities

(2010) Ja-Hyoung Ryu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Cross-Linked Polymer Nanogels: A Versatile Nanoscopic Drug Delivery Platform

(2010) Ja-Hyoung Ryu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA Polyplexes Formed Using PEGylated Biodegradable Hyperbranched Polymers

(2010) Lei Tao et al.   MACROMOLECULAR BIOSCIENCE

PEGylated Functional Nanoparticles from a Reactive Homopolymer Scaffold Modified by Thiol Addition Chemistry

(2010) LingJiun Wong et al.   MACROMOLECULES

Glycopolymer Decoration of Gold Nanoparticles Using a LbL Approach

(2010) Cyrille Boyer et al.   MACROMOLECULES

Novel Strategy for ROP of NCAs Using Thiols As Initiators: Synthesis of Diblock Copolymers Based on Polypeptides

(2010) Xuewei Zhang et al.   MACROMOLECULES

Influence of End Groups on the Stimulus-Responsive Behavior of Poly[oligo(ethylene glycol) methacrylate] in Water

(2010) Peter J. Roth et al.   MACROMOLECULES

Hairy Hollow Microspheres of Fluorescent Shell and Temperature-Responsive Brushes via Combined Distillation-Precipitation Polymerization and Thiol−ene Click Chemistry

(2010) Guo Liang Li et al.   MACROMOLECULES

Highly Branched and Hyperbranched Glycopolymers via Reversible Addition−Fragmentation Chain Transfer Polymerization and Click Chemistry

(2010) Mona Semsarilar et al.   MACROMOLECULES

Combining Thio−Bromo “Click” Chemistry and RAFT Polymerization: A Powerful Tool for Preparing Functionalized Multiblock and Hyperbranched Polymers

(2010) Jiangtao Xu et al.   MACROMOLECULES

Nucleophile-Initiated Thiol-Michael Reactions: Effect of Organocatalyst, Thiol, and Ene

(2010) Justin W. Chan et al.   MACROMOLECULES

Facile Access to Polymeric Vesicular Nanostructures: Remarkable ω-End group Effects in Cholesterol and Pyrene Functional (Co)Polymers

(2010) Jiangtao Xu et al.   MACROMOLECULES

Novel polymer coupling chemistry based upon latent cysteine-like residues and thiazolidine chemistry

(2010) Joseph S. Carlson et al.   Polymer Chemistry

Conjugation of RAFT-generated polymers to proteins by two consecutive thiol–ene reactions

(2010) Ming Li et al.   Polymer Chemistry

Heterotelechelic polymers for capture and release of protein–polymer conjugates

(2010) Karina L. Heredia et al.   Polymer Chemistry

Protein conjugation of thermoresponsive amine-reactive polymers prepared by RAFT

(2010) Hongmei Li et al.   Polymer Chemistry

Functional polymers for optoelectronic applications by RAFT polymerization

(2010) Graeme Moad et al.   Polymer Chemistry

End-functional polymers, thiocarbonylthio group removal/transformation and reversible addition-fragmentation-chain transfer (RAFT) polymerization

(2010) Graeme Moad et al.   POLYMER INTERNATIONAL

Telechelic polymers by living and controlled/living polymerization methods

(2010) Mehmet Atilla Tasdelen et al.   PROGRESS IN POLYMER SCIENCE

Polymers for Drug Delivery Systems

(2010) William B. Liechty et al.   Annual Review of Chemical and Biomolecular Engineering

Quantum Dot−Block Copolymer Hybrids with Improved Properties and Their Application to Quantum Dot Light-Emitting Devices

(2009) Matthias Zorn et al.   ACS Nano

Improving the efficacy of combined modality anticancer therapy using HPMA copolymer-based nanomedicine formulations☆

(2009) Twan Lammers   ADVANCED DRUG DELIVERY REVIEWS

RAFT Polymer End-Group Modification and Chain Coupling/Conjugation Via Disulfide Bonds

(2009) Cyrille Boyer et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Synthesis of siRNA Polyplexes Adopting a Combination of RAFT Polymerization and Thiol-ene Chemistry

(2009) David Valade et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

The Power of RAFT for Creating Polymers Having Imbedded Side-Chain Functionalities: Norbornenyl-Functionalized Polymers and their Transformations via ROMP and Thiol-ene Reactions

(2009) Jun Ma et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Living Radical Polymerization by the RAFT Process – A Second Update

(2009) Graeme Moad et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Shell-Detachable Micelles Based on Disulfide-Linked Block Copolymer As Potential Carrier for Intracellular Drug Delivery

(2009) Ling-Yan Tang et al.   BIOCONJUGATE CHEMISTRY

Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies

(2009) Maarten van Dijk et al.   BIOCONJUGATE CHEMISTRY

Synthesis of a Pyridyl Disulfide End-Functionalized Glycopolymer for Conjugation to Biomolecules and Patterning on Gold Surfaces

(2009) Vimary Vázquez-Dorbatt et al.   BIOMACROMOLECULES

Functional Disulfide-Stabilized Polymer−Protein Particles

(2009) Zhongfan Jia et al.   BIOMACROMOLECULES

Synthesis of Hetero-Telechelic α,ω Bio-Functionalized Polymers

(2009) Peter J. Roth et al.   BIOMACROMOLECULES

Bio-reversible polyPEGylation

(2009) Lei Tao et al.   CHEMICAL COMMUNICATIONS

Synthesis of thiol-linked neoglycopolymers and thermo-responsive glycomicelles as potential drug carrier

(2009) Gaojian Chen et al.   CHEMICAL COMMUNICATIONS

One- pot synthesis and biofunctionalization of glycopolymers via RAFT polymerization and thiol–ene reactions

(2009) Cyrille Boyer et al.   CHEMICAL COMMUNICATIONS

Applications of Orthogonal “Click” Chemistries in the Synthesis of Functional Soft Materials

(2009) Rhiannon K. Iha et al.   CHEMICAL REVIEWS

Bioapplications of RAFT Polymerization

(2009) Cyrille Boyer et al.   CHEMICAL REVIEWS

Marrying click chemistry with polymerization: expanding the scope of polymeric materials

(2009) Patricia L. Golas et al.   CHEMICAL SOCIETY REVIEWS

Toward the Synthesis of the RareN-(Trifluoromethyl)amides and theN-(Difluoromethylene)-N-(trifluoromethyl)amines [RN(CF3)CF2R′] Using BrF3

(2009) Youlia Hagooly et al.   JOURNAL OF ORGANIC CHEMISTRY

Modification of RAFT-polymers via thiol-ene reactions: A general route to functional polymers and new architectures

(2009) Cyrille Boyer et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Sequential thiol-ene/thiol-ene and thiol-ene/thiol-yne reactions as a route to well-defined mono and bis end-functionalized poly(N-isopropylacrylamide)

(2009) Bing Yu et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Versatile ω-end group functionalization of RAFT polymers using functional methane thiosulfonates

(2009) Peter J. Roth et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Monodispersed Polymeric Nanocapsules: Spontaneous Evolution and Morphology Transition from Reducible Hetero-PEG PICmicelles by Controlled Degradation

(2009) Wen-Fei Dong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal “Relay” Reactions for Designing Functionalized Soft Nanoparticles

(2009) Hamilton Kakwere et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sequential Phosphine-Catalyzed, Nucleophilic Thiol−Ene/Radical-Mediated Thiol−Yne Reactions and the Facile Orthogonal Synthesis of Polyfunctional Materials

(2009) Justin W. Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hetero-Telechelic Dye-Labeled Polymer for Nanoparticle Decoration

(2009) Peter J. Roth et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Efficient Usage of Thiocarbonates for Both the Production and the Biofunctionalization of Polymers

(2009) Cyrille Boyer et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Synthesis of Functionalized and Biodegradable Hyperbranched Polymers from Novel AB2Macromonomers Prepared by RAFT Polymerization

(2009) Jiangtao Xu et al.   MACROMOLECULES

Trapping of Thiol-Terminated Acrylate Polymers with Divinyl Sulfone To Generate Well-Defined Semitelechelic Michael Acceptor Polymers

(2009) Gregory N. Grover et al.   MACROMOLECULES

The Thiol−Isocyanate Click Reaction: Facile and Quantitative Access to ω-End-Functional Poly(N,N-diethylacrylamide) Synthesized by RAFT Radical Polymerization

(2009) Haibo Li et al.   MACROMOLECULES

Surface Modification of Poly(divinylbenzene) Microspheres via Thiol−Ene Chemistry and Alkyne−Azide Click Reactions

(2009) Anja S. Goldmann et al.   MACROMOLECULES

Synthesis of Maleimide-End-Functionalized Star Polymers and Multimeric Protein−Polymer Conjugates

(2009) Lei Tao et al.   MACROMOLECULES

Synthesis of Heterotelechelic α,ω Dye-Functionalized Polymer by the RAFT Process and Energy Transfer between the End Groups

(2009) Peter J. Roth et al.   MACROMOLECULES

Macromolecular Engineering through Click Chemistry and Other Efficient Transformations

(2009) Brent S. Sumerlin et al.   MACROMOLECULES

Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer

(2009) Craig L. Duvall et al.   MOLECULAR PHARMACEUTICS

Biotinylated disulfide containing PEI/avidin bioconjugate shows specific enhanced transfection efficiency in HepG2 cells

(2009) Xuan Zeng et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

RAFT polymerization and thiol-ene modification of 2-vinyloxyethyl methacrylate: Towards functional branched polymers

(2009) Zhongfan Jia et al.   POLYMER

A new approach to 3-miktoarm star polymers using a combination of reversible addition–fragmentation chain transfer (RAFT) and ring opening polymerization (ROP) via “Click” chemistry

(2009) Ankit Vora et al.   POLYMER

End group removal and modification of RAFT polymers

(2009) Helen Willcock et al.   Polymer Chemistry

Direct RAFT polymerization of an unprotected isocyanate-containing monomer and subsequent structopendant functionalization using “click”-type reactions

(2009) Joel D. Flores et al.   Polymer Chemistry

Thiol-ene “click” reactions and recent applications in polymer and materials synthesis

(2009) Andrew B. Lowe   Polymer Chemistry

Biopolymer-based microgels/nanogels for drug delivery applications

(2009) Jung Kwon Oh et al.   PROGRESS IN POLYMER SCIENCE

Synthesis of functional polymers with controlled architecture by CRP of monomers in the presence of cross-linkers: From stars to gels

(2009) Haifeng Gao et al.   PROGRESS IN POLYMER SCIENCE

Stimuli-responsive amphiphilic (co)polymers via RAFT polymerization

(2009) Adam E. Smith et al.   PROGRESS IN POLYMER SCIENCE

Future perspectives and recent advances in stimuli-responsive materials

(2009) Debashish Roy et al.   PROGRESS IN POLYMER SCIENCE

Temperature-Responsive Self-Assembled Monolayers of Oligo(ethylene glycol): Control of Biomolecular Recognition

(2008) Hadi M. Zareie et al.   ACS Nano

The Emergence of Thiol-Ene Coupling as a Click Process for Materials and Bioorganic Chemistry

(2008) Alessandro Dondoni   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Biodegradable Poly(disulfide amine)s for Gene Delivery with High Efficiency and Low Cytotoxicity

(2008) Mei Ou et al.   BIOCONJUGATE CHEMISTRY

Synthesis of Versatile Thiol-Reactive Polymer Scaffolds via RAFT Polymerization

(2008) Lingjiun Wong et al.   BIOMACROMOLECULES

One-Pot Conversion of RAFT-Generated Multifunctional Block Copolymers of HPMA to Doxorubicin Conjugated Acid- and Reductant-Sensitive Crosslinked Micelles

(2008) Zhongfan Jia et al.   BIOMACROMOLECULES

Degradable Disulfide Core-Cross-Linked Micelles as a Drug Delivery System Prepared from Vinyl Functionalized Nucleosides via the RAFT Process

(2008) Ling Zhang et al.   BIOMACROMOLECULES

Heterofunctional polymers and core–shell nanoparticles via cascade aminolysis/Michael addition and alkyne–azide click reaction of RAFT polymers

(2008) Zesheng An et al.   CHEMICAL COMMUNICATIONS

An approach to biodegradable star polymeric architectures using disulfide coupling

(2008) Jingquan Liu et al.   CHEMICAL COMMUNICATIONS

Reversible siRNA–polymer conjugates by RAFT polymerization

(2008) Karina L. Heredia et al.   CHEMICAL COMMUNICATIONS

Convergent synthesis of 3-arm star polymers from RAFT-prepared poly(N,N-diethylacrylamide) via a thiol–ene click reaction

(2008) Justin W. Chan et al.   CHEMICAL COMMUNICATIONS

Disulfide-cross-linked PEG-poly(amino acid)s copolymer micelles for glutathione-mediated intracellular drug delivery

(2008) Ahn Na Koo et al.   CHEMICAL COMMUNICATIONS

Stability and utility of pyridyl disulfide functionality in RAFT and conventional radical polymerizations

(2008) Cyrille Boyer et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

End group transformations of RAFT‐generated polymers with bismaleimides: Functional telechelics and modular block copolymers

(2008) Ming Li et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Approach to peptide decorated micelles via RAFT polymerization

(2008) Jingquan Liu et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Facile postpolymerization end-modification of RAFT polymers

(2008) Jason M. Spruell et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Imparting Nanoparticle Function with Size-Controlled Amphiphilic Polymers

(2008) Yingchuan Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PEG-Detachable Polyplex Micelles Based on Disulfide-Linked Block Catiomers as Bioresponsive Nonviral Gene Vectors

(2008) Seiji Takae et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembling Diblock Copolymers of Poly[N-(2-hydroxypropyl)methacrylamide] and aβ-Sheet Peptide

(2008) Larisa Cristina Radu et al.   MACROMOLECULAR BIOSCIENCE

Synthesis of Lipid-α-End-Functionalized Chains by RAFT Polymerization. Stabilization of Lipid/Polymer Particle Assemblies

(2008) Maël Bathfield et al.   MACROMOLECULES

Reversible Addition Fragmentation Chain Transfer (RAFT) and Hetero-Diels−Alder Chemistry as a Convenient Conjugation Tool for Access to Complex Macromolecular Designs

(2008) Andrew J. Inglis et al.   MACROMOLECULES

Direct Synthesis of Well-Defined Heterotelechelic Polymers for Bioconjugations

(2008) Cyrille Boyer et al.   MACROMOLECULES

Dual Stimuli-Responsive Nanogels by Self-Assembly of Polysaccharides Lightly Grafted with Thiol-Terminated Poly(N-isopropylacrylamide) Chains

(2008) Nobuyuki Morimoto et al.   MACROMOLECULES

A Method for Obtaining Defined End Groups of Polymethacrylates Prepared by the RAFT Process during Aminolysis

(2008) Peter J. Roth et al.   MACROMOLECULES

Well-Defined Polymers Bearing Pendent Alkene Functionalities via Selective RAFT Polymerization

(2008) Jun Ma et al.   MACROMOLECULES

Thiol−Yne Photopolymerizations: Novel Mechanism, Kinetics, and Step-Growth Formation of Highly Cross-Linked Networks

(2008) Benjamin D. Fairbanks et al.   MACROMOLECULES

Biodistribution and Pharmacokinetic Studies of Bone-TargetingN-(2-Hydroxypropyl)methacrylamide Copolymer−Alendronate Conjugates

(2008) Huaizhong Pan et al.   MOLECULAR PHARMACEUTICS

Synthesis of Thiocarbamates from Thiols and Isocyanates Under Catalyst- and Solvent-Free Conditions

(2008) Barahman Movassagh et al.   MONATSHEFTE FUR CHEMIE

Temperature and redox responsive hydrogels from ABA triblock copolymers prepared by RAFT polymerization

(2008) Andrew P. Vogt et al.   Soft Matter