Journal
MACROMOLECULAR BIOSCIENCE
Volume 13, Issue 7, Pages 885-892Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/mabi.201200452
Keywords
acid-responsive; drug delivery systems; electrospun; fibrous scaffolds; tissue engineering
Funding
- National Natural Science Foundation of China [51003058, 81271999, 81171437]
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Acid-responsive electrospun fibers are fabricated by introducing sodium bicarbonate into PLLA fibers using an emulsion method. This novel electrospun fibrous scaffold exhibits a rapid acid-responsive controlled drug release (early stage) and stable three-dimensional (3D) structure as a tissue engineering scaffold (late stage) for cell growth.
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