Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods

Comparison of separation techniques for the elucidation of IgG N-glycans pooled from healthy mammalian species

(2014) Barbara Adamczyk et al.   CARBOHYDRATE RESEARCH

LC-MS/MS Peptide Mapping with Automated Data Processing for Routine Profiling of N-Glycans in Immunoglobulins

(2014) Bhavana Shah et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Comparative Performance of Four Methods for High-throughput Glycosylation Analysis of Immunoglobulin G in Genetic and Epidemiological Research

(2014) Jennifer E. Huffman et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry

(2013) Bo Wang et al.   ANALYST

Unraveling the Glyco-Puzzle: Glycan Structure Identification by Capillary Electrophoresis

(2013) Stefan Mittermayr et al.   ANALYTICAL CHEMISTRY

Capillary Electrophoresis/Mass Spectrometry of APTS-Labeled Glycans for the Identification of Unknown Glycan Species in Capillary Electrophoresis/Laser-Induced Fluorescence Systems

(2013) Svenja-Catharina Bunz et al.   ANALYTICAL CHEMISTRY

Rapid Fc glycosylation analysis of Fc fusions with IdeS and liquid chromatography mass spectrometry

(2013) Heather Lynaugh et al.   mAbs

High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer

(2013) Dietmar Reusch et al.   mAbs

Interlaboratory Study on Differential Analysis of Protein Glycosylation by Mass Spectrometry: The ABRF Glycoprotein Research Multi-Institutional Study 2012

(2013) Nancy Leymarie et al.   MOLECULAR & CELLULAR PROTEOMICS

Analysis of urinary oligosaccharides in lysosomal storage disorders by capillary high-performance anion-exchange chromatography–mass spectrometry

(2012) Cees Bruggink et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples

(2012) Dietmar Reusch et al.   ANALYTICAL BIOCHEMISTRY

Alignment of laser-induced fluorescence and mass spectrometric detection traces using electrophoretic mobility scaling in CE-LIF-MS of labeled N-glycans

(2012) Carolin Huhn et al.   ELECTROPHORESIS

Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities

(2012) Shan Chung et al.   mAbs

Increased serum clearance of oligomannose species present on a human IgG1 molecule

(2012) Leslie Alessandri et al.   mAbs

High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans

(2011) A. M. Goetze et al.   GLYCOBIOLOGY

Intravenous gammaglobulin suppresses inflammation through a novel TH2 pathway

(2011) Robert M. Anthony et al.   NATURE

NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic

(2011) Adam W Barb et al.   Nature Chemical Biology

Immunoglobulin G Glycopeptide Profiling by Matrix-Assisted Laser Desorption Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

(2010) Maurice H. J. Selman et al.   ANALYTICAL CHEMISTRY

Ultra Performance Liquid Chromatographic Profiling of SerumN-Glycans for Fast and Efficient Identification of Cancer Associated Alterations in Glycosylation

(2010) Jonathan Bones et al.   ANALYTICAL CHEMISTRY

Towards the implementation of quality by design to the production of therapeutic monoclonal antibodies with desired glycosylation patterns

(2010) Ioscani Jimenez del Val et al.   BIOTECHNOLOGY PROGRESS

Optimized Workflow for Preparation of APTS-Labeled N-Glycans Allowing High-Throughput Analysis of Human Plasma Glycomes using 48-Channel Multiplexed CGE-LIF

(2010) L. Renee Ruhaak et al.   JOURNAL OF PROTEOME RESEARCH

Chinese hamster ovary cells can produce galactose-α-1,3-galactose antigens on proteins

(2010) Carlos J Bosques et al.   NATURE BIOTECHNOLOGY

A systematic approach to protein glycosylation analysis: a path through the maze

(2010) Karina Mariño et al.   Nature Chemical Biology

Glycan analysis by modern instrumental methods

(2010) Martin Pabst et al.   PROTEOMICS

Expression systems for therapeutic glycoprotein production

(2009) Yves Durocher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Development of a high performance anion exchange chromatography analysis for mapping of oligosaccharides

(2009) Carl Grey et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Separation of 2-aminobenzamide labeled glycans using hydrophilic interaction chromatography columns packed with 1.7μm sorbent

(2009) Joomi Ahn et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Comparison of Methods for ProfilingO-Glycosylation

(2009) Yoshinao Wada et al.   MOLECULAR & CELLULAR PROTEOMICS

Glycosylation as a strategy to improve antibody-based therapeutics

(2009) Roy Jefferis   NATURE REVIEWS DRUG DISCOVERY

IgG glycosylation analysis

(2009) Carolin Huhn et al.   PROTEOMICS

Glycosylation profiling of a therapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer

(2008) Amareth Lim et al.   ANALYTICAL BIOCHEMISTRY

On-Line CE−LIF−MS Technology for the Direct Characterization of N-Linked Glycans from Therapeutic Antibodies

(2008) Lynn A. Gennaro et al.   ANALYTICAL CHEMISTRY

Editorial [Hot Topic: Therapeutic Antibodies and Derivatives: From the Bench to the Clinic(Guest Editor: Alain Beck)]

(2008) A. Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Trends in Glycosylation, Glycoanalysis and Glycoengineering of Therapeutic Antibodies and Fc-Fusion Proteins

(2008) Alain Beck et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

N-glycan analysis by CGE-LIF: Profiling influenza A virus hemagglutininN-glycosylation during vaccine production

(2008) Jana Schwarzer et al.   ELECTROPHORESIS

Identification and quantification of N-linked oligosaccharides released from glycoproteins: An inter-laboratory study

(2008) S. Thobhani et al.   GLYCOBIOLOGY

Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease

(2008) V. Padler-Karavani et al.   GLYCOBIOLOGY

Comparison of LC and LC/MS methods for quantifying N-glycosylation in recombinant IgGs

(2008) Sandipan Sinha et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mass spectrometry for structural characterization of therapeutic antibodies

(2008) Zhongqi Zhang et al.   MASS SPECTROMETRY REVIEWS

HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software

(2007) Louise Royle et al.   ANALYTICAL BIOCHEMISTRY