Sortase-catalyzed in vitro functionalization of a HER2-specific recombinant Fab for tumor targeting of the plant cytotoxin gelonin

Trastuzumab emtansine in breast cancer

(2013) Luc Y Dirix et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Design optimization and characterization of Her2/neu-targeted immunotoxins: comparative in vitro and in vivo efficacy studies

(2013) Y Cao et al.   ONCOGENE

Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies

(2012) G. Borthakur et al.   HAEMATOLOGICA

Marketed therapeutic antibodies compendium

(2012) Janice M. Reichert   mAbs

Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by sortase A-mediated protein ligation

(2011) Mariusz P. Madej et al.   BIOTECHNOLOGY AND BIOENGINEERING

Challenges associated with the targeted delivery of gelonin to claudin-expressing cancer cells with the use of activatable cell penetrating peptides to enhance potency

(2011) Xiaoqin Yuan et al.   BMC CANCER

In vitro Sortagging of an Antibody Fab Fragment: Overcoming Unproductive Reactions of Sortase with Water and Lysine Side Chains

(2011) Sina Möhlmann et al.   CHEMBIOCHEM

Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer

(2011) Howard A. Burris et al.   Clinical Breast Cancer

Immunoconjugates Against Solid Tumors: Mind the Gap

(2011) A D Ricart   CLINICAL PHARMACOLOGY & THERAPEUTICS

Architects at the bacterial surface — sortases and the assembly of pili with isopeptide bonds

(2011) Antoni P. A. Hendrickx et al.   NATURE REVIEWS MICROBIOLOGY

Protein-Protein Fusion Catalyzed by Sortase A

(2011) David A. Levary et al.   PLoS One

Convergent Potency of Internalized Gelonin Immunotoxins across Varied Cell Lines, Antigens, and Targeting Moieties

(2010) Christopher M. Pirie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase – Structural and modeling insight into its functions

(2009) Hui-Guang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Construction and Characterization of Novel, Recombinant Immunotoxins Targeting the Her2/neu Oncogene Product: In vitro and In vivo Studies

(2009) Y. Cao et al.   CANCER RESEARCH

Cell Lines as Candidate Reference Materials for Quality Control of ERBB2 Amplification and Expression Assays in Breast Cancer

(2009) Y. Xiao et al.   CLINICAL CHEMISTRY

Engineered protein scaffolds as next-generation antibody therapeutics

(2009) Michaela Gebauer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method

(2009) Yoshihiro Kobashigawa et al.   JOURNAL OF BIOMOLECULAR NMR

Development trends for therapeutic antibody fragments

(2009) Aaron L Nelson et al.   NATURE BIOTECHNOLOGY

Anti-HER2 Treatment and Breast Cancer: State of the Art, Recent Patents, and New Strategies

(2009) Lorenzo Daniele et al.   Recent Patents on Anti-Cancer Drug Discovery

Antibody-Drug Conjugates for Cancer Therapy

(2008) Paul J. Carter et al.   CANCER JOURNAL

Site-Specific Protein Modification on Living Cells Catalyzed by Sortase

(2008) Tsutomu Tanaka et al.   CHEMBIOCHEM

Peptide−Sugar Ligation Catalyzed by Transpeptidase Sortase:  A Facile Approach to Neoglycoconjugate Synthesis

(2008) Sharmishtha Samantaray et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipid Modification of Proteins through Sortase-Catalyzed Transpeptidation

(2008) John M. Antos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY