Development of an Fn14 agonistic antibody as an anti-tumor agent

An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells

(2011) Nicholas S. Wilson et al.   CANCER CELL

TNF-like weak inducer of apoptosis (TWEAK) and TNF-α cooperate in the induction of keratinocyte apoptosis

(2011) Maya Zimmermann et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Death Receptor Agonists as a Targeted Therapy for Cancer

(2010) J. Wiezorek et al.   CLINICAL CANCER RESEARCH

Antibodies to TWEAK Receptor Inhibit Human Tumor Growth through Dual Mechanisms

(2010) P. A. Culp et al.   CLINICAL CANCER RESEARCH

Combination of Two Insulin-Like Growth Factor-I Receptor Inhibitory Antibodies Targeting Distinct Epitopes Leads to an Enhanced Antitumor Response

(2010) J. Dong et al.   MOLECULAR CANCER THERAPEUTICS

TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling

(2009) A Wicovsky et al.   CELL DEATH AND DIFFERENTIATION

Tumor Necrosis Factor: Renaissance as a Cancer Therapeutic?

(2008) D. Daniel et al.   CURRENT CANCER DRUG TARGETS

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

(2008) James E. Vince et al.   JOURNAL OF CELL BIOLOGY

The Fibroblast Growth Factor-Inducible 14 Receptor Is Highly Expressed in HER2-Positive Breast Tumors and Regulates Breast Cancer Cell Invasive Capacity

(2008) A. L. Willis et al.   MOLECULAR CANCER RESEARCH