A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin

The tumour-targeting human L19-IL2 immunocytokine: Preclinical safety studies, phase I clinical trial in patients with solid tumours and expansion into patients with advanced renal cell carcinoma

(2010) Manfred Johannsen et al.   EUROPEAN JOURNAL OF CANCER

The Immunocytokine F8-IL2 Improves the Therapeutic Performance of Sunitinib in a Mouse Model of Renal Cell Carcinoma

(2010) Katharina Frey et al.   JOURNAL OF UROLOGY

Biopharmaceutical benchmarks 2010

(2010) Gary Walsh   NATURE BIOTECHNOLOGY

Isolation and characterization of an inhibitory human monoclonal antibody specific to the urokinase-type plasminogen activator, uPA

(2010) D. Sgier et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Expression, engineering and characterization of the tumor-targeting heterodimeric immunocytokine F8-IL12

(2010) Roberto Sommavilla et al.   PROTEIN ENGINEERING DESIGN & SELECTION

New Strategy for the Extension of the Serum Half-Life of Antibody Fragments

(2009) Sabrina Trüssel et al.   BIOCONJUGATE CHEMISTRY

Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumors enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients

(2009) S. Sauer et al.   BLOOD

Human monoclonal antibodies targeting carbonic anhydrase IX for the molecular imaging of hypoxic regions in solid tumours

(2009) J K J Ahlskog et al.   BRITISH JOURNAL OF CANCER

Isolation and characterization of human monoclonal antibodies specific to MMP-1A, MMP-2 and MMP-3

(2009) Stefanie Pfaffen et al.   EXPERIMENTAL CELL RESEARCH

Three clinical-stage tumor targeting antibodies reveal differential expression of oncofetal fibronectin and tenascin-C isoforms in human lymphoma

(2009) Christoph Schliemann et al.   LEUKEMIA RESEARCH

Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis

(2009) Kathrin Schwager et al.   ARTHRITIS RESEARCH & THERAPY

Mild Hypothermia Improves Transient Gene Expression Yields Several Fold in Chinese Hamster Ovary Cells

(2008) S. Wulhfard et al.   BIOTECHNOLOGY PROGRESS

A high-affinity human monoclonal antibody specific to the alternatively spliced EDA domain of fibronectin efficiently targets tumor neo-vasculaturein vivo

(2008) Alessandra Villa et al.   INTERNATIONAL JOURNAL OF CANCER

Internalization via Antennapedia protein transduction domain of an scFv antibody toward c-Myc protein

(2007) C. Avignolo et al.   FASEB JOURNAL