Mining human antibody repertoires

Engineering Antibody Heavy Chain CDR3 to Create a Phage Display Fab Library Rich in Antibodies That Bind Charged Carbohydrates

(2014) S. Schoonbroodt et al.   JOURNAL OF IMMUNOLOGY

Golimumab

(2010) Sohini Mazumdar et al.   mAbs

Antibodies to watch in 2010

(2010) Janice M. Reichert   mAbs

An improved yeast transformation method for the generation of very large human antibody libraries

(2010) Lorenzo Benatuil et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A large library based on a novel (CH2) scaffold: Identification of HIV-1 inhibitors

(2009) Xiaodong Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display

(2009) S. Baskar et al.   BLOOD

Human B cell memory

(2009) Antonio Lanzavecchia et al.   CURRENT OPINION IN IMMUNOLOGY

Efficient Recovery of High-Affinity Antibodies from a Single-Chain Fab Yeast Display Library

(2009) Laura M. Walker et al.   JOURNAL OF MOLECULAR BIOLOGY

Monoclonal antibodies for cancer immunotherapy

(2009) Louis M Weiner et al.   LANCET

Old mice retain bone marrow B1 progenitors, but lose B2 precursors, and exhibit altered immature B cell phenotype and light chain usage

(2009) Sarah Alter-Wolf et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

Antigen-specific human polyclonal antibodies from hyperimmunized cattle

(2009) Yoshimi Kuroiwa et al.   NATURE BIOTECHNOLOGY

Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming

(2009) Mark J Kwakkenbos et al.   NATURE MEDICINE

A rapid and efficient single-cell manipulation method for screening antigen-specific antibody–secreting cells from human peripheral blood

(2009) Aishun Jin et al.   NATURE MEDICINE

Twenty years of combinatorial antibody libraries, but how well do they mimic the immunoglobulin repertoire?

(2009) M. A. A. Persson   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

(2009) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

(2009) L. M. Walker et al.   SCIENCE

Prophylactic and therapeutic activity of fully human monoclonal antibodies directed against Influenza A M2 protein

(2009) Roger R Beerli et al.   Virology Journal

The coming of age of virus-like particle vaccines

(2008) Gary T. Jennings et al.   BIOLOGICAL CHEMISTRY

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Fully human antibodies from transgenic mouse and phage display platforms

(2008) Nils Lonberg   CURRENT OPINION IN IMMUNOLOGY

Immunogenicity of anti-tumor necrosis factor antibodies—toward improved methods of anti-antibody measurement

(2008) Lucien Aarden et al.   CURRENT OPINION IN IMMUNOLOGY

Considerations for the development of therapeutic monoclonal antibodies

(2008) Patrick G Swann et al.   CURRENT OPINION IN IMMUNOLOGY

Translational applications of antibody phage display

(2008) Don L. Siegel   IMMUNOLOGIC RESEARCH

Hybridoma populations enriched for affinity-matured human IgGs yield high-affinity antibodies specific for botulinum neurotoxins

(2008) Sharad P. Adekar et al.   JOURNAL OF IMMUNOLOGICAL METHODS

An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies

(2008) Xiaocong Yu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Synthetic Antibody Libraries Focused Towards Peptide Ligands

(2008) Christian W. Cobaugh et al.   JOURNAL OF MOLECULAR BIOLOGY

The Human Combinatorial Antibody Library HuCAL GOLD Combines Diversification of All Six CDRs According to the Natural Immune System with a Novel Display Method for Efficient Selection of High-Affinity Antibodies

(2008) Christine Rothe et al.   JOURNAL OF MOLECULAR BIOLOGY

Generation, Affinity Maturation, and Characterization of a Human Anti-Human NKG2D Monoclonal Antibody with Dual Antagonistic and Agonistic Activity

(2008) Ka Yin Kwong et al.   JOURNAL OF MOLECULAR BIOLOGY

Construction of a Large Phage-Displayed Human Antibody Domain Library with a Scaffold Based On a Newly Identified Highly Soluble, Stable Heavy Chain Variable Domain

(2008) Weizao Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors

(2008) Xiaocong Yu et al.   NATURE

Rapid cloning of high-affinity human monoclonal antibodies against influenza virus

(2008) Jens Wrammert et al.   NATURE

Isolation of human monoclonal antibodies by mammalian cell display

(2008) R. R. Beerli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein evolution with an expanded genetic code

(2008) C. C. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

(2008) B. Mietzner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial surrobody libraries

(2008) L. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA