Antibody drug-conjugates targeting the tumor vasculature

Alterations in vascular architecture and permeability following OXi4503 treatment

(2009) Lie Sam Chan et al.   ANTI-CANCER DRUGS

Antibody-Drug Conjugates for Cancer Therapy

(2008) Paul J. Carter et al.   CANCER JOURNAL

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody-Cytotoxic Drug Conjugate

(2008) G. D. Lewis Phillips et al.   CANCER RESEARCH

Tumor blood flow interruption after radiotherapy strongly inhibits tumor regrowth

(2008) Katsuyoshi Hori et al.   CANCER SCIENCE

Potent Anticarcinoma Activity of the Humanized Anti-CD70 Antibody h1F6 Conjugated to the Tubulin Inhibitor Auristatin via an Uncleavable Linker

(2008) E. Oflazoglu et al.   CLINICAL CANCER RESEARCH

Monoclonal Antibodies as Innovative Therapeutics

(2008) Janice Reichert   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Phase I clinical evaluation of ZD6126, a novel vascular-targeting agent, in patients with solid tumors

(2008) Patricia M. LoRusso et al.   INVESTIGATIONAL NEW DRUGS

A Phase II Study of ABT-751 in Patients with Advanced Non-small Cell Lung Cancer

(2008) Ann M. Mauer et al.   Journal of Thoracic Oncology

Combination of antiangiogenesis with chemotherapy for more effective cancer treatment

(2008) J. Ma et al.   MOLECULAR CANCER THERAPEUTICS

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index

(2008) Jagath R Junutula et al.   NATURE BIOTECHNOLOGY

Development trends for new cancer therapeutics and vaccines

(2007) J REICHERT   DRUG DISCOVERY TODAY