Association of serum B cell activating factor from the tumour necrosis factor family (BAFF) and a proliferation-inducing ligand (APRIL) with central nervous system and renal disease in systemic lupus erythematosus

Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus

(2012) William Stohl et al.   ARTHRITIS AND RHEUMATISM

Effect of belimumab treatment on renal outcomes: results from the phase 3 belimumab clinical trials in patients with SLE

(2012) MA Dooley et al.   LUPUS

Potential role of IFNα in adult lupus

(2012) Lars Rönnblom   ARTHRITIS RESEARCH & THERAPY

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus

(2011) Richard Furie et al.   ARTHRITIS AND RHEUMATISM

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic opportunities in systemic lupus erythematosus: state of the art and prospects for the new decade

(2010) G. K. Bertsias et al.   ANNALS OF THE RHEUMATIC DISEASES

Raised serum level of APRIL in patients with systemic lupus erythematosus: Correlations with disease activity indices

(2010) M. Hegazy et al.   CLINICAL IMMUNOLOGY

B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B cell maturation antigen-immunoglobulin

(2010) Stacey R Dillon et al.   ARTHRITIS RESEARCH & THERAPY

The Lupus Susceptibility Locus Sle1 Breaches Peripheral B Cell Tolerance at the Antibody-Forming Cell and Germinal Center Checkpoints

(2009) R. Vuyyuru et al.   JOURNAL OF IMMUNOLOGY

Serum levels of tumour necrosis factor family members a proliferation-inducing ligand (APRIL) and B lymphocyte stimulator (BLyS) are inversely correlated in systemic lupus erythematosus

(2008) J Morel et al.   ANNALS OF THE RHEUMATIC DISEASES

Lack of association between the interferon-  signature and longitudinal changes in disease activity in systemic lupus erythematosus

(2008) C Landolt-Marticorena et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

(2008) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

(2008) E. Belnoue et al.   BLOOD

Raised intrathecal levels of APRIL and BAFF in patients with systemic lupus erythematosus: relationship to neuropsychiatric symptoms

(2008) Annie George-Chandy et al.   ARTHRITIS RESEARCH & THERAPY