Journal
LUPUS
Volume 21, Issue 11, Pages 1237-1239Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0961203312449492
Keywords
Systemic lupus erythematosus (SLE); protein-losing enteropathy; premature ovarian failure (POF); autoimmune oophoritis; cyclosporine
Categories
Funding
- National Science Council Taiwan [NSC100-2314-B075-025]
- Taipei Veterans General Hospital [V100-C-079, V100E4-001, V100-A-010]
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Protein-losing enteropathy (PLE) and autoimmune oophoritis are unusual manifestations of systemic lupus erythematosus (SLE). Autoimmune oophoritis may result in menstrual disturbance and spontaneous premature ovarian failure. However, there is no validated examination to confirm the diagnosis and it is easily neglected in patients with ovarian insufficiency. A 31-year-old woman with SLE presented with PLE and autoimmune oophoritis during the long course of flares and remissions in her lupus activity. The synchronism implied the association between the two. Moreover, both conditions simultaneously had a good response to cyclosporine A (CsA) therapy. Lupus (2012) 21, 1237-1239.
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