Journal
LUNG CANCER
Volume 82, Issue 3, Pages 506-508Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.lungcan.2013.08.030
Keywords
RANK; RANKL; Denosumab; ALK; Crizotinib; Non small cell lung cancer; NF-kappa B
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Here we report the case of a patient with metastatic adenocarcinoma of the lung harboring an ALK gene translocation. In this patient a response of the primary tumor and metastases has been detected upon treatment with denosumab. A possible link between ALK and RANK is postulated. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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