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Oncology
Clement Bouron, Clara Mathie, Valerie Seegers, Olivier Morel, Pascal Jezequel, Hamza Lasla, Camille Guillerminet, Sylvie Girault, Marie Lacombe, Avigaelle Sher, Franck Lacoeuille, Anne Patsouris, Aude Testard
Summary: The aim of this study was to evaluate PET/CT parameters for determining different prognostic groups in triple-negative breast cancer (TNBC). The study found that MTV, TLG, and entropy could be of interest in predicting the prognostic outcome of TNBC patients. Textural features associated with metabolic and volumetric parameters of baseline [F-18]FDG PET/CT have a prognostic value for identifying high-relapse-risk groups in early TNBC patients.
Article
Oncology
Jianlin Wang, Xiaopeng Yu, Aiqi Shi, Long Xie, Liqun Huang, Yingrui Su, Jinshun Zha, Jiangyan Liu
Summary: The study aimed to investigate the predictive value of pre-treatment F-18-FDG PET/CT multi-metabolic parameters and tumor metabolic heterogeneity for gastric cancer prognosis. The results showed that a metabolic heterogeneity index called HI-1 was an independent risk factor for patient prognosis, and could be used to guide personalized treatment.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Oncology
Xiufang Qiu, Haixia Wu, Ting Xu, Shihan Xie, Ziqing You, Yixin Hu, Yinghong Zheng, Zewei Liang, Chaoxiong Huang, Li Yi, Li Li, Jing Liu, Zhaodong Fei, Chuanben Chen
Summary: This study aimed to reassess the clinical significance of standardized uptake values (SUVs) in nasopharyngeal carcinoma (NPC) on F-18-fluorodeoxyglucose (F-18-FDG) positron-emission tomography (PET). The results showed that high SUVs were associated with cancer recurrence, and the SUVmax-NTR ratio was identified as a potential prognostic factor.
Article
Medicine, General & Internal
Aruki Tanaka, Tetsuro Sekine, Edwin E. G. W. ter Voert, Konstantinos G. Zeimpekis, Gaspar Delso, Felipe de Galiza Barbosa, Geoffrey Warnock, Shin-ichiro Kumita, Patrick Veit Haibach, Martin Huellner
Summary: This study investigated the reproducibility of tracer uptake measurements obtained by TOF-PET-CT and TOF-PET-MR, finding no statistical difference in liver regions but some underestimation of metrics in tumor lesions by PET-MR. Strong correlations were observed for MTV and TLG between PET-CT and PET-MR on VOI40 and VOI50.
FRONTIERS IN MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jin Qi, Elizabeth Kurian, Orhan K. oez
Summary: Hibernomas are rare benign tumors originating from fetal brown adipose tissue. They can occur in various parts of the body, with thigh, shoulder, back, and neck being the most common locations, and are rarely found in the abdominal cavity, retroperitoneum, breast, bones, scrotum, and perirectum. We present a case of a 58-year-old woman with a mediastinal mass, who was incidentally found to have an FDG-avid fat-containing lesion in the omentum abutting the stomach.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Oncology
Joohee Lee, Young Seok Cho, Jhingook Kim, Young Mog Shim, Kyung-Han Lee, Joon Young Choi
Summary: This study retrospectively reviewed data from 83 patients with thymic epithelial tumors who underwent pretreatment F-18-FDG PET/CT, and found that SUVavg and Masaoka stage were independent prognostic factors for progression-free survival in thymic epithelial tumors.
Article
Oncology
Jian-Wei Yang, Ling-Ling Yuan, Yan Gao, Xu-Sheng Liu, Yu-Jiao Wang, Lu-Meng Zhou, Xue-Yan Kui, Xiao-Hui Li, Chang-Bin Ke, Zhi-Jun Pei
Summary: The study found a correlation between the expression levels of EIF2S2 gene and F-18-FDG PET/CT metabolic parameters in CRC patients, and a positive correlation between EIF2S2 and GLUT1 expression. Overexpression of EIF2S2 in CRC can promote glycolysis.
Article
Radiology, Nuclear Medicine & Medical Imaging
Noam Nissan, Israel Sandler, Michal Eifer, Yael Eshet, Tima Davidson, Hanna Bernstine, David Groshar, Miri Sklair-Levy, Liran Domachevsky
Summary: Compared with lactating patients without breast cancer, the F-18-FDG uptake in lactating tissue of PABC patients is significantly decreased.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
Dong-Joo Shin, Hongyoon Choi, Dong Kyu Oh, Hyun Pil Sung, Jun-Hyeong Kim, Dong-Hyun Kim, Soo-Yeon Kim
Summary: This study investigated the correlation between SUV of F-18-FDG PET/CT and conductivity parameters in breast cancer. The results showed a low positive correlation between SUVpeak and mean conductivity in breast cancer, suggesting that conductivity has the potential to be a noninvasive predictor of lymphovascular invasion (LVI) status.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xingyu Mu, Xiaoxue Huang, Zewen Jiang, Meng Li, Lulu Jia, Zhongyuan Lv, Wei Fu, Jingsong Mao
Summary: This study compared the diagnostic performance of two PET/CT techniques in patients with differentiated thyroid cancer. The results showed that [F-18]FAPI-42 PET/CT is comparable to 2-[F-18]FDG PET/CT in detecting lesions and reflecting FAP expression.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sung Ryul Shim, Seong-Jang Kim
Summary: This study evaluated the diagnostic accuracies of F-18-FDG PET or PET/CT for Merkel cell carcinoma (MCC) through a systematic review and meta-analysis. The results showed that F-18-FDG PET/CT had excellent performance in diagnosing MCC and could be useful for exclusion and confirmation of the disease. Further large multicenter studies are needed to validate its diagnostic accuracy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jie Ding, Jiangdong Qiu, Zhixin Hao, Hua Huang, Qiaofei Liu, Wenjing Liu, Chao Ren, Marcus Hacker, Taiping Zhang, Wenming Wu, Xiang Li, Li Huo
Summary: This study evaluated the performance of [(68) Ga]Ga-FAPI-04 and [F-18]F-FDG PET/CT on the disease staging and prognostic value of patients with localized PDAC. The results showed that [(68) Ga]Ga-FAPI-04 was more sensitive and accurate than [F-18]F-FDG, and could be used for staging and prognostic evaluation of PDAC, providing a non-invasive guide for clinical management.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Oncology
Jun Liu, Yukun Si, Ziang Zhou, Xu Yang, Cuicui Li, Luodan Qian, Li Juan Feng, Mingyu Zhang, Shu Xin Zhang, Jie Liu, Ying Kan, Jianhua Gong, Jigang Yang
Summary: This study aimed to evaluate the prognostic value of intratumoral metabolic heterogeneity in primary tumor lesions of neuroblastoma (NB) patients. The results showed that intratumoral metabolic heterogeneity of primary lesions was associated with event-free survival (EFS), and patients with higher intratumoral metabolic heterogeneity and bone marrow involvement (BMI) had worse outcomes.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Yun Chen, Shan Zheng, Zenan Wu, Yanmin Lin, Weibing Miao
Summary: A 76-year-old man with yellowish discoloration of sclera and skin for 2 months was referred for F-18-FDG PET/CT to characterize a mass in the pancreas. PET/CT images showed intense FDG uptake in the head of the pancreas, with a lymph nodal mass in the hepatic hilar region, consistent with pancreatic malignancy. Histopathologic findings confirmed diffuse large B-cell lymphoma with no evidence of adenocarcinoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Medicine, General & Internal
Ricarda Hinzpeter, Seyed Ali Mirshahvalad, Roshini Kulanthaivelu, Vanessa Murad, Claudia Ortega, Ur Metser, Zhihui Amy Liu, Elena Elimova, Rebecca K. S. Wong, Jonathan Yeung, Raymond W. Jang, Patrick Veit-Haibach
Summary: We investigated the prognostic value of sarcopenia measurements and metabolic parameters derived from F-18-FDG-PET/CT in patients with esophageal and gastroesophageal cancer. The results showed that sarcopenia status was significantly associated with survival prognosis, while standard metabolic parameters did not show significant correlation. Therefore, the combination of clinical parameters and sarcopenia status is a more effective indicator for predicting survival prognosis in patients with advanced gastroesophageal cancer.