Article
Chemistry, Physical
Saad H. Al-Thaqafy, Abdullah M. Asiri, Mohie E. M. Zayed, Md. Zafer Alam, Arif Ahmad, Masroor Fatima, Sanjay Kumar, Salman A. Khan
Summary: An efficient one-pot synthesis of MPMO was developed using 1-methylpyrrole-2-carbaldehyde, hippuric acid, and NaOAc. The solvatochromic properties of MPMO were investigated by studying its absorption and emission spectra in solvents of different polarities. MPMO showed a red shift in emission and absorption maximum as the solvent polarity increased. The interaction of MPMO with CTAB and SDS was used to determine their critical micellar concentration. Additionally, fluorescence quenching of MPMO by AgNPs and its antibacterial activity against Gram-negative bacteria were observed.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Optics
Debasmita Kandi, Sriram Mansingh, Arjun Behera, Kulamani Parida
Summary: In this study, it was found that among the colloidal CdS quantum dots prepared in four common solvents capped with thioglycolic acid (TGA), those in dimethyl sulfoxide (DMSO) exhibited the highest relative fluorescence quantum yield, reaching 93%. Additionally, Urbach energy was calculated to provide insight into the density of states in the CdS quantum dots.
JOURNAL OF LUMINESCENCE
(2021)
Article
Environmental Sciences
Oded Liran
Summary: This study presents a structural equation that relates chlorophyll fluorescence to actual photosynthetic activity and introduces a new spectral index. The relation between the new spectral index and seasonal growth of corn was examined, indicating a close correlation.
Article
Chemistry, Multidisciplinary
Cecilia Cerretani, Mikkel B. Liisberg, Vanessa Ruck, Jiro Kondo, Tom Vosch
Summary: The effect of replacing guanosines with inosines in the stabilizing strands of NIR emissive DNA-Ag16NC was studied. The spectroscopic behavior of the inosine mutants varied depending on the position, with a shorter fluorescence decay time when guanosine at position 7 was replaced and a longer decay time when inosine was at position 9. The observed changes could be explained by the structural information obtained from single crystal X-ray diffraction measurements.
NANOSCALE ADVANCES
(2022)
Article
Chemistry, Analytical
Yulu Liu, Lei Cao, Minghui Zan, Jiahui Peng, Panyong Wang, Xinpei Pang, Yan Zhang, Li Li, Wen-Fei Dong, Qian Mei
Summary: In this study, cyan fluorescent silicon quantum dots were synthesized for the rapid detection of chlorogenic acid (CGA), an important bioactive component in plants. The SiQDs showed high sensitivity and selectivity in detecting CGA, providing a valuable platform for biological and pharmaceutical analysis with broad application prospects.
Article
Biotechnology & Applied Microbiology
Su-Dan Jiang, Yi Sheng, Xian-Jun Wu, Yong-Li Zhu, Ping-Ping Li
Summary: CBCRs are phytochrome-related photoreceptor proteins in cyanobacteria covering a wide spectral range with potential applications as biomarkers and biosensors. A novel PEB-binding CBCR GAF domain was identified, exhibiting intense orange fluorescence with high quantum yield, selective and instantaneous quenching by copper ions, and reversibility upon treatment with EDTA, suggesting its potential as a biosensor for rapid copper ion detection.
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Spectroscopy
Manal A. Alossaimi, Abdulmalik S. A. Altamimi, Heba Elmansi, Galal Magdy
Summary: A new spectrofluorimetric method based on nitrogen-doped carbon quantum dots (N-CQDs) fluorescent probes was proposed for the determination of larotrectinib. The method is simple, involves no pre-treatment steps or complicated techniques, and showed sufficient sensitivity for the analysis of the drug. The synthesized N-CQDs exhibited high fluorescence intensity, allowing for the selective quenching and sensitive determination of larotrectinib.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Food Science & Technology
Wenshuo Zhang, Hongda Zhong, Pingping Zhao, Aiguo Shen, Houbin Li, Xinghai Liu
Summary: Carbon quantum dots (CDs) show great potential in detecting food ingredients and contaminants due to their easy preparation, good biocompatibility, and adjustable modification. The design of probes for CDs can be categorized into three types, with the introduction of functional groups on the surface being a key factor. The intermolecular interactions of different target substances play a role in determining the choice of carbon source and synthesis method.
Review
Chemistry, Multidisciplinary
Xinzhe Xiao, Yumin Zhang, Lei Zhou, Bin Li, Lin Gu
Summary: Graphene oxide (GO) is an excellent photoluminescence (PL) material with unique optical properties. It has been widely used in various fields such as material science and biomedicine. The luminescence mechanism of GO and GOQDs is still not fully understood, but they show potential in medical imaging and biosensors.
Article
Physics, Multidisciplinary
B. Bisht, S. Pant, M. Giri
Summary: In this study, static and dynamic fluorescence analyses of direct yellow 27 were conducted in various solvents, showing a redshifted emission peak with increasing solvent polarity and differences in excited-state lifetime in different solvents. The fluorescence quantum yield in water was calculated as 0.41 with solvent-dependent variations.
INDIAN JOURNAL OF PHYSICS
(2022)
Article
Spectroscopy
Mohamed Ahmed Abdel Hamid, Samar H. Elagamy, Aya Gamal, Fotouh R. Mansour
Summary: A simple and eco-friendly microwave method was used to prepare highly fluorescent nitrogen and sulfur co-doped carbon quantum dots (NS-CQDs) for the determination of ascorbic acid (ASC) in pharmaceutical dosage forms. The NS-CQDs were prepared within one minute using citric acid and L-cysteine. The fluorescence of NS-CQDs was quenched by ferric ions but could be restored by the addition of ASC due to its reducing properties.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Yanfang Niu, Sen Li, Junning Zhang, Wang Wan, Zhenzhu He, Jun Liu, Keliang Liu, Sainan Ren, Liqin Ge, Xin Du, Zhongze Gu
Summary: A simple method using photodynamic surface chemistry based on disulfide bonds was proposed to create high-resolution, low-cost, dynamically rewritable multicolor fluorescence patterns. The fluorescence patterns exhibited high stability after storing for 100 days.
Review
Chemistry, Analytical
Myriam Diaz-Alvarez, Antonio Martin-Esteban
Summary: This paper reviews the development of optical sensors using a combination of quantum dots and molecularly imprinted polymers. These sensors overcome the limitations of traditional analytical methods and improve sensor selectivity and sensitivity.
Article
Chemistry, Physical
Zoya Zaheer, Samia A. Kosa, Mohd Akram
Summary: UV-visible and fluorescence spectroscopic methods were used to study the binding capabilities of Ag+ ions and AgNPs with bovine serum albumin (BSA), revealing that BSA acted as a ligand for both and showing significant fluorescence quenching. It was found that Ag+ ions had stronger binding and quenching efficiency towards BSA compared to AgNPs, with the distance between tryptophan and acceptor affecting the energy transfer process.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Spectroscopy
Furkan Burak Sen, Nilay Begic, Mustafa Bener, Resat Apak
Summary: In this study, a fluorescent polyethylenimine capped carbon quantum dots (PEI-C-dots) probe was synthesized and used to detect TNT residues. The synthesized PEI-C-dots exhibited high fluorescence quantum yield and low detection limit for TNT. The detection of TNT was not interfered by similar structured explosives, common soil ions, and camouflage agents.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Biochemistry & Molecular Biology
Akshay Uttarkar, Alice Preethi Kishore, Sudhanva M. Srinivas, Shobith Rangappa, Raviraj Kusanur, Vidya Niranjan
Summary: This study evaluated the therapeutic effect of a coumarin derivative called 2-(2-(6-methyl-2-hydroxy-chromen-4-yl)acetamido)-3-phenylpropanoic acid on triple negative breast cancer. The compound was found to bind with Frizzled-7 protein and showed inhibitory effects on breast cancer cell lines in vitro.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Chemistry, Physical
Kalpana Sharma, Raveendra Melavanki, Sudhir M. Hiremath, Raviraj Kusanur, H. S. Geethanjali, Nagaraja Nagaraja
Summary: In this study, the compounds 3-(2,4-Dichloro-phenyl)-1-pyridin-3-yl-propenone (3DPP) and 5-Phenyl-1-pyridin-3yl-penta-2,4-dien-1-one (5PPD) were synthesized and characterized using spectroscopic and computational methods. The optimized structures and geometric parameters were obtained and compared with experimental data. Molecular docking studies and other analyses were performed to understand the properties of these compounds.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Article
Chemistry, Analytical
Raveendra Melavanki, Vijaya Kumar, Diksha Singh, Nishant Dhiman, Varsha V. Koppal, N. R. Patil
Summary: This study investigates the fluorescence quenching mechanism of quinilone yellow and its potential application in the field of nonlinear optics. The results show significant energy transfer and collisional quenching between metal ions and SQDS molecules.
Article
Physics, Multidisciplinary
R. F. Chinnappagoudra, M. D. Kamatagi, N. R. Patil, N. S. Sankeshwar
Summary: The lattice thermal conductivity (LTC) of cadmium arsenide (Cd3As2) has been studied over a wide temperature range using the Callaway model. The study shows the relative importance of different scattering mechanisms on the LTC. It is found that for low temperatures, LTC fits well with the experimental data, but for high temperatures, the contribution of electronic scattering mechanisms needs to be considered.
Article
Chemistry, Multidisciplinary
Varsha V. Koppal, Raveendra Melavanki, Raviraj Kusanur, Zabin K. Bagewadi, Deepak A. Yaraguppi, Sanjay H. Deshpande, Ninganagouda R. Patil
Summary: This study investigates the fluorescence quenching behavior of a nonfluorescent aniline and a fluorophore in binary solvent mixtures and explores the antimicrobial potential of the fluorophore. The findings shed light on the importance of organic molecules in medicine and pharmaceuticals, particularly in therapeutic applications. The study demonstrates the effectiveness of the quenching models used and confirms the presence of static quenching reactions. Additionally, in silico and bioinformatics tools were employed to assess the druglike and antimicrobial activities of the fluorophore, yielding promising insights.
Article
Chemistry, Physical
Dayanand N. Patagar, Sheetal R. Batakurki, Raviraj Kusanur, Swarna M. Patra, S. Saravanakumar, Manjunath Ghate
Summary: A series of benzimidazole tethered coumarin-3-carboxamide analogues were synthesized and tested for their antioxidant potential using DPPH and ABTS assays. The compounds also demonstrated moderate alpha-amylase inhibition. Compound 10j showed the highest DPPH radical scavenging activity with an IC50 value of 89.57 μM, while compound 10f exhibited the strongest scavenging activity against ABTS radicals with an IC50 value of 93.45 μM. Compound 10f also emerged as the best antidiabetic analogue with an IC50 value of 67.52 μM.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Physical
H. S. Rashmi, K. A. Vishnumurthy, K. H. Girish, Kusanur Raviraj
Summary: The present work focused on the synthesis and characterization of o-aminophenol-aniline copolymer with Ni-ZnFe 2 O 4 nano composite for selective recognition of NO 2 gas. The polymer composite sensors showed excellent specificity and sensitivity at room temperature, and exhibited stable performance.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Biochemistry & Molecular Biology
Vidya Niranjan, Sanjana Jayaprasad, Akshay Uttarkar, Raviraj Kusanur, Jitendra Kumar
Summary: Breast cancer is a heterogeneous disease and the second leading cause of cancer-related deaths among women. Plant-based derivatives and their derivatives are safer than synthetic compounds in combating chemoresistance. In this study, a template-based design of a coumarin derivative was developed to target the ADP-sugar pyrophosphatase protein. Molecular docking, molecular dynamics simulation, and metadynamics studies were performed, demonstrating the stable interaction and potential anticancer activity of the designed coumarin derivative. In vitro validation using a cytotoxicity assay confirmed its effectiveness.
Article
Polymer Science
Rashmi Hulimane Shivaswamy, Vishnumurthy Kanive Bagilu Ananthapadmanabha, Raviraj Kusanur
Summary: A copolymer of pyrrole and o-aminophenol was synthesized using single step oxidative polymerization technique, and two nanocomposites were prepared. The sensitivity of the composites was higher than the pure polymer, and they exhibited good selectivity and repeatability for acetone gas. The nanocomposites containing Co-Fe2O3 and α-Fe2O3 showed faster response and recovery time towards the target gas. Both the polymer and nanocomposites demonstrated excellent repeatability.
POLYMERS FOR ADVANCED TECHNOLOGIES
(2023)
Article
Oncology
Vidya Niranjan, R. Vibha, Sarah Philip, Akshay Uttarkar, Raviraj Kusanur, Jitendra Kumar
Summary: This study utilized computer aided drug design techniques to screen and validate novel imidazopyrazine derivatives for breast cancer. The results showed that these derivatives had potential anti-cancer activity, laying a foundation for future precise counting and research of new synthetic compounds.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Anagha S. Setlur, Chandrashekar Karunakaran, V. Anusha, Aditya A. Shendre, Akshay Uttarkar, Vidya Niranjan, H. G. Ashok Kumar, Raviraj Kusanur
Summary: This study synthesized two quinoline derivatives and demonstrated their antibacterial activity against Bacillus subtilis through toxicity predictions and molecular docking. The results showed that these derivatives had little to no toxicity and effectively inhibited the growth of Bacillus subtilis.
MOLECULAR BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Raveendra Melavanki, Raviraj Kusanur, Kalpana Sharma, Kishor Kumar Sadasivuni, V. V. Koppal, N. R. Patil
Summary: The present study reports the use of spectroscopic techniques to analyze pyridine derivatives, specifically pyridine-based chalones. The solvatochromic behavior of 3DPP in different solvents, both polar and non-polar, was experimentally investigated. The compound's photophysical properties in various solvents were attributed to intra-molecular charge transfer interactions. The study also involved theoretical and experimental estimation of the dipole moment of 3DPP using solvatochromic methods, and observed a bathochromic shift in the emission spectra confirming the pi ->pi* transition. Fluorescence quenching of 3DPP and its mechanism were studied, as well as the energy transfer between 3DPP and metal ions using FRET theory.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Deepak A. Yaraguppi, Zabin K. Bagewadi, Ninganagouda R. Patil, Nitin Mantri
Summary: This comprehensive review examines iturin, a cyclic lipopeptide originating from Bacillus subtilis and related bacteria. These compounds have potent inhibitory effects against plant disease-causing bacteria and fungi, making them valuable in bio-pesticides and mycosis treatment. Additionally, iturin exhibits diverse features such as anticancer and hemolytic effects, and finds applications across industries such as food, petroleum, pharmaceuticals, and cosmetics.
Article
Chemistry, Physical
Dayanand N. Patagar, Raviraj Kusanur, Sheetal R. Batakurki, Swarna M. Patra, Ninganagouda R. Patil, Jagadish H. Patil
Summary: A series of 8-benzimidazolyl-coumarin-3-oxadiazoles were synthesized and evaluated for their anti-cancer activity against breast cancer. Compound 10b with 2,4-dimethyl phenyl substitution on the oxadiazole ring showed the highest potency with an IC50 value of 9.26 μg/mL compared to the standard drug doxorubicin. The compounds 10g, 10c, and 10e also showed significant anti-cancer activity and exhibited similar amino acid interactions as doxorubicin when docked with the receptor protein quinone reductase-2.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Proceedings Paper
Materials Science, Multidisciplinary
H. S. Rashmi, K. A. Vishnumurthy, Raviraj Kusanur
Summary: A conjugated copolymer of aniline and pyrrole was synthesized, and copolymer/ZnO nanocomposite thin films were prepared using oxidative polymerization technique. The research findings showed that the nanocomposite exhibited good sensitivity and selectivity towards methanol vapours at room temperature.
MATERIALS TODAY-PROCEEDINGS
(2022)