Article
Spectroscopy
Qi Hu, Si Chen, Fang Chen
Summary: A convenient chemiluminescence method for thiourea determination was proposed based on the thiourea quenching of the chemiluminescence of Tb3+/ prulifloxacin sensitized KMnO4-Na2SO3 system. The method showed linear calibration graphs in a certain concentration range with satisfactory spiked recoveries. Additionally, a possible mechanism of sensitization and quenching was proposed to explain the process.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Physical
Mahnaz Alizadeh, Mahmoud Zarei, Masoud Ebratkhahan, Mohammad Amjadi
Summary: The study investigated the effects and catalytic properties of various nanomaterials on permanganate chemiluminescence systems, with silver nanoprisms showing a significant enhancing effect on the system.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Multidisciplinary
Carsten Peukert, Sachin Popat Gholap, Ori Green, Lukas Pinkert, Joop van den Heuvel, Marco van Ham, Doron Shabat, Mark Broenstrup
Summary: Conjugating siderophore moieties with enzyme-activatable dioxetanes resulted in trifunctional probes with high signal-to-background ratios, allowing for sensitive and selective detection of bacteria. The efficient iron transport capability into bacteria was confirmed through a growth recovery assay, highlighting the potential applications of these probes in bacterial detection.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biochemistry & Molecular Biology
Irina Chernukha, Nadezhda Kupaeva, Elena Kotenkova, Daniil Khvostov
Summary: The effective management of agro-industry organic waste for developing high-commercial-value products is a promising facet of the circular economy. Red onion husks exhibited the highest antioxidant potential and flavonoid content among the different onion colors.
Article
Chemistry, Analytical
Khair Un Nisa, Attiq Ur Rehman Kakar, Muhammad Asghar, Arif Samiullah, Naqeebullah, Niamatullah, Arif Shah
Summary: A flow injection (FI) methodology using the acidic potassium permanganate (KMnO4)-rhodamine-B (Rh-B) reaction with chemiluminescence (CL) detection was developed for the determination of acetochlor and cartap-HCl pesticides in freshwater samples. The method showed good linearity and sensitivity, with LODs and LOQs as low as 7.5 x 10(-4) mg L-1 and 2.5 x 10(-3) mg L-1, respectively. The method was able to accurately estimate the concentrations of acetochlor and cartap-HCl in spiked freshwater samples, with recoveries ranging from 93% to 112% and 98% to 109%, respectively. The most probable CL reaction mechanism was also explored.
Article
Chemistry, Multidisciplinary
Jing Liu, Jingsheng Huang, Xin Wei, Penghui Cheng, Kanyi Pu
Summary: Chemotherapy-induced peripheral neuropathy (CIPN) is common in cancer patients but poorly managed due to the lack of reliable diagnostic techniques. In this study, a near-infrared chemiluminophore (MPBD) was synthesized and developed into a water-soluble activatable probe (CalCL) for in vivo imaging of CIPN. The probe allows for sensitive detection of paclitaxel-mediated CIPN in living mice, which is not achievable with fluorescence imaging. This research not only develops a highly efficient chemiluminescent probe, but also presents the first optical imaging approach for high-throughput screening of neurotoxic drugs.
ADVANCED MATERIALS
(2023)
Article
Engineering, Biomedical
Maja Rankovic, Anka Jevremovic, Aleksandra Janosevic Lezaic, Aleksandar Arsenijevic, Jelena Rupar, Vladimir Dobricic, Bojana Nedic Vasiljevic, Nemanja Gavrilov, Danica Bajuk-Bogdanovic, Maja Milojevic-Rakic
Summary: Acridine and its derivatives (9-chloroacridine and 9-aminoacridine) supported on zeolite Y were investigated for their potential as delivery systems for anticancer agents. Drug loading was successfully achieved on the zeolite surface, with the highest drug release observed for zeolite-supported 9-aminoacridine. The cytotoxicity of the supported acridines on colorectal carcinoma cells was improved by the zeolite carrier, especially for zeolite-impregnated 9-aminoacridine.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Carla M. Magalhaes, Patricia Gonzalez-Berdullas, Mariana Pereira, Diana Duarte, Nuno Vale, Joaquim C. G. Esteves da Silva, Luis Pinto da Silva
Summary: Cancer is a challenging disease to treat, and this study focuses on the design, synthesis, and evaluation of different brominated coelenteramines as potential anticancer molecules. The results highlight the importance of the 4-bromophenyl moiety for their anticancer activity and suggest independent mechanisms of action compared to coelenterazines. One of the studied coelenteramines showed promise in improving the profile of a known chemotherapeutic agent.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Lini Huo, Xiaochen Liu, Yogini Jaiswal, Hao Xu, Rui Chen, Rumei Lu, Yaqin Nong, Leonard Williams, Yan Liang, Zhiruo Jia
Summary: We designed and synthesized a series of novel acridine-triazole and acridine-thiadiazole derivatives. These compounds showed high levels of antitumor activity against gastric cancer cells and bladder cancer cells, while exhibiting low toxicity to normal liver cells. Moreover, their pharmacological mechanisms and effects on cell cycle and apoptosis were evaluated. Furthermore, these compounds demonstrated low cytotoxicity to zebrafish but strong inhibition of the formation of zebrafish sub-intestinal veins, suggesting potential clinical applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Engineering, Environmental
Shule Duan, Huiyu Dong, Pin Hou, Zhimin Qiang
Summary: This study investigated the yield, kinetics, stoichiometry, and abatement of trace organic contaminants (TrOC) by the permanganate/bisulfite (MS) and permanganate/manganous (MM) processes. The results showed that the TrOC abatement rate in the MS process was significantly higher than that in the MM process, despite the higher rate constant of Mn(III) generation in the former. The contribution of Mn(III) to TrOC abatement was limited in both processes.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biology
Ching-Te Kuo, Yu-Sheng Lai, Siang-Rong Lu, Hsinyu Lee, Hsiu-Hao Chang
Summary: Personalized drug cocktails have become popular in cancer treatment due to their use of drug combinations for better efficacy. In this study, a microcrater-arrayed (mu CA) chip was developed using laser direct writing to optimize cell amount and reagent usage. The results showed that the mu CA chip had better drug prediction accuracy compared to the conventional assay. This research has important implications for high-throughput drug screening and personalized medicine.
Article
Chemistry, Analytical
Jinglong Fang, Li Dai, Ruiqing Feng, Xiang Ren, Dan Wu, Wei Cao, Qin Wei, Hongmin Ma
Summary: In this research, the biomimetic engineering metal-organic framework (MOF-818) was used to achieve an ultrasensitive electrochemiluminescence (ECL) immunoassay of disease markers. By synthesizing a hydrogen-bonded organic framework (HOF) containing luminol and three active ligands, the ECL luminescence activity was improved. MOF-818 with biomimetic superoxide dismutase (SOD) and catalase (CAT) activities were then used as quenching agents for a sandwich immunoassay mode. The enzyme activity resulted in the decrease in luminol ECL signal responsiveness. The detection limit for carcinoembryonic antigen (CEA) was found to be 0.457 pg/mL within a range of 0.001-50 ng/mL. This novel sandwich sensing model based on enzyme activity provides a meaningful potential tool for precise detection, expanding the broader application of nanoenzymes in analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Engineering, Environmental
Yanghai Yu, Tiansheng Chen, Xiaohong Guan, Hongyu Dong, Junlian Qiao
Summary: This study introduces green polyaspartic acid as both reducing and chelating agents to improve the oxidation capacity and utilization efficiency of permanganate. The stabilized Mn(III) species generated in the Mn(VII)/PASP system dominates the degradation of bisphenol A and selectively oxidizes organic contaminants. This work identifies a new approach for high oxidation capacity and efficient utilization of Mn(VII) in oxidation processes.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Correction
Nanoscience & Nanotechnology
Souvik Kay, Saptarshi Banerjee, Amit Kumar Singh, Mamata Ojha, Arindam Mondal, N. D. Pradeep Singh
Summary: Combination therapy is an effective strategy to improve treatment outcomes and reduce side effects. Researchers developed a dual-arm acridine photocage capable of releasing two active molecules simultaneously, which demonstrated improved anticancer efficacy and real-time fluorescence monitoring in vitro.
ACS APPLIED NANO MATERIALS
(2022)
Article
Plant Sciences
Hesham Farouk Oraby
Summary: The current study shows the potential of using maize silk as a platform for the biosynthesis of cerium oxide nanoparticles, which exhibit strong scavenging potential and can be used to detect phenolic compounds with great sensitivity.
Article
Chemistry, Analytical
Maryam Naebi, Masoumeh Arabli Jamshidi, Mir Ali Farajzadeh, Jafar Abolhassni, Mohammad Reza Afshar Mogaddam
JOURNAL OF SEPARATION SCIENCE
(2020)
Article
Chemistry, Applied
Nafiseh Bagheri, Haider A. J. Al Lawati, Javad Hassanzadeh
Summary: A microfluidic device was developed for simultaneous analysis of total flavonoids and total phenolic acids, utilizing magnetic ZIF-4 for separation and sensitive detection. The method showed high accuracy and recovery rates, proving successful in analyzing tea and honey samples.
Article
Chemistry, Analytical
Iman Al Yahyai, Javad Hassanzadeh, Haider A. J. Al-Lawati
Summary: A paper-based analytical device combined with a chemiluminescence system was established for the determination of deltamethrin using polyphosphate on graphene quantum dots-KMnO4 CL reaction. The mechanism of the CL emission was proposed and the method showed effective detection of DM residue in food samples with a sensitive and reliable approach.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Maliheh Amirzehni, Javad Hassanzadeh, Behrouz Vahid
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Chemistry, Analytical
Nafiseh Bagheri, Haider A. J. Al Lawati, Nada A. Al Sharji, Javad Hassanzadeh
Summary: The 2D metal-organic framework (MOF) proved to be an efficient adsorbent for simultaneous extraction of fluoroquinolones (FQs). The use of acetic acid solution for elution showed high recovery without the need for toxic organic solvents. The method demonstrated great selectivity and sensitivity in detecting OF, NOR, and CIP in milk samples.
Article
Chemistry, Analytical
Mitra Azimi, Jamshid L. Manzoori, Mohammad Amjadi, Jafar Abolhasani
Summary: A sulfur and nitrogen co-doped carbon quantum dot-potassium permanganate chemiluminescence system was developed for the determination of trace amounts of deltamethrin, showing increased chemiluminescence in optimized conditions proportional to deltamethrin concentration. The method, with simple setup and high sensitivity, utilized characterization techniques to prepare the carbon quantum dots and successfully applied to water samples for deltamethrin determination.
JOURNAL OF ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Mitra Azimi, Jamshid L. Manzoori, Mohammad Amjadi, Jafar Abolhasani
Summary: A simple and novel method for the determination of acetamiprid in water samples is suggested, based on the reducing effect of acetamiprid on the chemiluminescence intensity of S, N-CQDs. The study found that acetamiprid diminishes the chemiluminescence intensity by competing with S, N-CQDs, providing a proportional reduction for acetamiprid determination.
ANALYTICAL SCIENCES
(2021)
Article
Chemistry, Analytical
Habibeh Eskandari, Maliheh Amirzehni, Esmaeil Safavi, Javad Hassanzadeh
Summary: In this study, a powerful method for determining cefixime was developed using ZnMOF@MGO for extraction and preconcentration, followed by HPLC for analysis. The combination of these techniques resulted in a sensitive and selective analytical detection method.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Haider A. J. Al Lawati, Javad Hassanzadeh, Nafiseh Bagheri, Iman Al Lawati
Summary: A novel paper-based chemiluminescence assay was developed with smartphone readout for on-site and reliable analytical applications. The system utilized the high-performance cobalt-imidazole metal-organic framework (CoMOF) to improve luminol-hydrogen peroxide (H2O2) CL emission, leading to intense emission and good reproducibility. Coupled with the stability enhancement of luminol, the device showed potential for commercialization and was made more accessible to the public by using a smartphone as a detector.
Article
Chemistry, Physical
Reyhaneh Kouchakinejad, Shahab Shariati, Jafar Abolhasani, Ebrahim Ghorbani Kalhor, Mohammad Taghi Vardini
Summary: A new type of magnetic nanoparticles was studied as an adsorbent for removing paraquat from water. The key factors affecting the adsorption efficiency were identified, and the optimal adsorption model and properties were determined through kinetic and thermodynamic studies.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Correction
Food Science & Technology
Ebrahim Ghorbani-Kalhor, Mohammad Behbahani, Jafar Abolhasani, Rahim Hosseinzadeh Khanmiri
FOOD ANALYTICAL METHODS
(2022)
Article
Chemistry, Analytical
Shiva Rashidi, Ebrahim Ghorbani-Kalhor, Bahaaldin Rashidzadeh, Jafar Abolhasani
Summary: This study describes the synthesis of a novel meso/magnetic adsorbent based on chitosan nanocomposite hydrogel to remove heavy metal ions from aqueous solutions. The adsorption process of Hg (II) ions was found to be highly selective and efficient. The maximum adsorption capacity of Hg (II) ions was 579.8 mg/g.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2022)
Correction
Chemistry, Applied
Mohammad Behbahani, Jafar Abolhasani, Mostafa M. Amini, Omid Sadeghi, Fariborz Omidi, Akbar Bagheri, Mani Salarian
Article
Chemistry, Analytical
Ali Hassanzadeh, Ebrahim Ghorbani-Kalhor, Khalil Farhadi, Jafar Abolhasani
Summary: This study evaluated the feasibility of using GO/Na2SiO3 nanocomposite as an efficient adsorbent for the removal of malachite green dye. The nanosorbent was characterized and optimized, and the adsorption process was found to follow pseudo-second order kinetic models and Freundlich isotherm. Thermodynamic analysis showed that the adsorption process was spontaneous and exothermic. The prepared adsorbent also showed good reusability without a significant decrease in removal efficiency.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY RESEARCH
(2022)
Article
Chemistry, Analytical
Iman Al Yahyai, Haider A. J. Al-Lawati, Javad Hassanzadeh
Summary: This study developed an environmentally friendly paper-based analytical device for accurate detection of bendiocarb pesticide. By enhancing the chemiluminescent reaction of sulfur, nitrogen-doped carbon quantum dots and potassium permanganate with sulfite ions, the chemiluminescence emission was intensively enhanced.
ANALYTICAL METHODS
(2021)
