Article
Agricultural Engineering
Barbara Alberghini, Federica Zanetti, Massimiliano Corso, Stephanie Boutet, Loic Lepiniec, Angela Vecchi, Andrea Monti
Summary: Camelina is an oilseed crop with agronomic and qualitative characteristics that make it suitable for multiple bio-based applications. This study compared six camelina cultivars in terms of their agronomic characteristics, oil composition, and specialized metabolites content and composition. The results showed that different cultivars have different characteristics and that growing conditions can influence the content of specialized metabolites.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Nutrition & Dietetics
Jeremy Bellien, Erwan Bozec, Frederic Bounoure, Hakim Khettab, Julie Malloizel-Delaunay, Mohamed Skiba, Michele Iacob, Nathalie Donnadieu, Aude Coquard, Beatrice Morio, Brigitte Laillet, Jean-Paul Rigaudiere, Jean-Michel Chardigny, Christelle Monteil, Cathy Vendeville, Alain Mercier, Anne-Francoise Cailleux, Anne Blanchard, Jacques Amar, Leopold K. Fezeu, Bruno Pannier, Alessandra Bura-Riviere, Pierre Boutouyrie, Robinson Joannides
Summary: This study assessed the cardiovascular and metabolic effects of camelina oil in hypertensive patients with metabolic syndrome. The results showed that camelina oil supplementation did not improve vascular function but adversely affected glucose metabolism.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Foteini Angelopoulou, Ioannis Roussis, Ioanna Kakabouki, Antonios Mavroeidis, Vassilios Triantafyllidis, Dimitrios Beslemes, Chariklia Kosma, Panteleimon Stavropoulos, Eleni Tsiplakou, Dimitrios Bilalis
Summary: Camelina seed cake cultivated with compost fertilization and conventional tillage is found to be an effective alternative to conventionally used protein feed ingredients, which meets the increasing demand for organic feed in the market.
APPLIED SCIENCES-BASEL
(2023)
Article
Nanoscience & Nanotechnology
Mei-Qi Xu, Yan-Li Hao, Jing-Ru Wang, Zhuo-Yue Li, Hui Li, Zhen-Han Feng, Hui Wang, Jing-Wen Wang, Xuan Zhang
Summary: The study developed ALA-PTX NPs with high drug loading, simple preparation, and better biocompatibility. Results showed that ALA-PTX NPs exhibited superior cellular uptake and antitumor activity in vitro and in vivo.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2021)
Article
Geriatrics & Gerontology
R. De Giuseppe, I. Di Napoli, C. E. Tomasinelli, Alessandra Vincenti, G. Biino, E. Sommella, L. Ferron, P. Campiglia, F. Ferrara, P. M. Casali, H. Cena
Summary: This study aimed to investigate the effects of Camelina oil-enriched crackers on serum omega-3 concentration, inflammatory markers, and serum lipid profile. The results showed that consuming Camelina oil-enriched crackers significantly increased the serum concentration of alpha-linolenic acid, but had no significant effects on inflammatory markers and lipid profile.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Medicine, Research & Experimental
Hongshuai Lv, Weiping Jia, Li Yang, Peng Dong, Jiaojiao Liu, Si Wang, Xiaohai Li, Jinghua Hu, Ling Zhao, Yikang Shi
Summary: This study developed three dual drug conjugates by connecting unsaturated fatty acids with Cabazitaxel on dextran. The conjugates showed enhanced water solubility and antitumor effects, with dextran-GLA-CTX exhibiting the strongest activity.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Biochemistry & Molecular Biology
Prasad Parchuri, Anjali Pappanoor, Abdulrahman Naeem, Timothy P. Durrett, Ruth Welti, R. V. Sreedhar
Summary: Buglossoides arvensis is a burgeoning oilseed crop with a unique combination of omega-3 and omega-6 poly-unsaturated fatty acids. During seed development, DGATs play a crucial role in enriching TAGs with PUFA compared to PDATs.
Article
Plant Sciences
Melisa E. Yonny, Maria L. Toscano Adamo, Ariel Rodriguez Torresi, Guillaume Reversat, Binqging Zhou, Camille Oger, Jean-Marie Galano, Thierry Durand, Claire Vigor, Monica A. Nazareno
Summary: Abiotic stress induces the formation of reactive oxygen species (ROS) in plants, leading to oxidative stress and damage. Natural antioxidant extract can mitigate the negative effects of oxidative stress on melon and sweet pepper plants.
PHYSIOLOGIA PLANTARUM
(2023)
Article
Biochemistry & Molecular Biology
Tianyu Zhang, Lei Chen, Xiaofei Guo, Shan Li, Xin He, Shengjie Pei, Duo Li
Summary: Peony seed oil and fish oil improve cognitive dysfunction caused by mitochondrial dysfunction by increasing brain levels of 5hmC.
Article
Chemistry, Physical
Walter F. Schmidt, Fu Chen, C. Leigh Broadhurst, Jianwei Qin, Michael A. Crawford, Moon S. Kim
Summary: Polyunsaturated fatty acids, such as DHA, DPA, and EPA, have similar structures but differ in their biological activities and utilization in mammalian tissues. Among them, DHA plays a unique role in certain tissues and cannot be substituted by other fatty acids. Research shows that the conformational changes in DHA may be affected by structural analogs.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Applied
M. T. Ngo Njembe, E. Dormal, C. Gardin, E. Mignolet, C. Debier, Y. Larondelle
Summary: This study showed that supplementing laying hens' feeds with flaxseeds combined with oil from Ricinodendron heudelotii or Punica granatum seeds can increase the egg content of beneficial fatty acids, without affecting the conversion rate of ALA to DHA. Both oils efficiently converted into RmA, with Punica granatum seed oil having a higher accumulation of PunA in eggs.
Article
Agriculture, Multidisciplinary
Kin Sum Leung, Jean-Marie Galano, Yu Fung Yau, Camille Oger, Thierry Durand, Jetty Chung-Yung Lee
Summary: Walnuts contain high levels of ALA, phytoprostanes, and phytofurans, which can increase ALA and eicosapentaenoic acid levels, as well as elevate phytoprostanes and phytofurans in liver and heart tissues when consumed. Additionally, a walnut diet can reduce certain oxidative products in the body, induce the generation of anti-inflammatory lipid mediators in the liver.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Zhan Li, Ying Wang, Lili Yu, Yongzhe Gu, Lijuan Zhang, Jun Wang, Lijuan Qiu
Summary: The increasing problem of soil salinization has a severe impact on soybean growth and development, leading to reduced yields and posing a serious threat to global crop production. In this study, the PfFAD3a gene was isolated from perilla and overexpressed in soybeans to assess the salt tolerance of transgenic plants. The results showed that overexpression of PfFAD3a increased the expression of PfFAD3a and the content of ff-linolenic acid in transgenic soybean plants, significantly enhancing their salt tolerance. Physiological and biochemical analysis revealed that overexpression of PfFAD3a increased the chlorophyll content and maximum photochemical efficiency of transgenic soybean plants under salt stress, while reducing the accumulation of MDA, H2O2, and O-circle(2), and increasing the activities of SOD, POD, CAT, and APX, as well as the production of proline and soluble sugar. In conclusion, the overexpression of PfFAD3a enhances salt tolerance in transgenic soybean plants through improved membrane fluidity and increased antioxidant capacity induced by C18:3.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Daqian Sun, Weizhu Quan, Di Wang, Jingyan Cui, Tianyi Wang, Mei Lin, Yijin Wang, Nan Wang, Yuanyuan Dong, Xiaowei Li, Weican Liu, Fawei Wang
Summary: Through the analysis of the CsFAD gene family in Camelina and the functional study of CsFAD2-2, we identified that CsFAD2-2 is involved in fatty acid synthesis in Camelina.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Pharmacology & Pharmacy
Arja T. Erkkila, Suvi Manninen, Linda Fredrikson, Monika Bhalke, Minna Holopainen, Maija Ruuth, Maria Lankinen, Reijo Kakela, Katariina Oorni, Ursula S. Schwab
Summary: This study investigated the effects of alpha-linolenic acid and n-3 long chain polyunsaturated fatty acids on the LDL lipidome and aggregation of LDL particles. The results showed that consumption of Camelina sativa oil and fatty fish can modify the LDL lipidome to contain more polyunsaturated and less saturated lipid species. The surface lipids of LDL are associated with LDL aggregation.
JOURNAL OF CLINICAL LIPIDOLOGY
(2021)
Article
Environmental Sciences
Iwona Puzio, Grzegorz Tymicki, Marta Pawlowska-Olszewska, Marek Bienko, Radoslaw Piotr Radzki
ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE
(2020)
Article
Veterinary Sciences
Aneta Nowakiewicz, Przemyslaw Zieba, Sebastian Gnat, Aleksandra Troscianczyk, Marcelina Osinska, Dominik Lagowski, Urszula Kosior-Korzecka, Iwona Puzio
RESEARCH IN VETERINARY SCIENCE
(2020)
Article
Environmental Sciences
Aneta Nowakiewicz, Przemyslaw Zieba, Sebastian Gnat, Aleksandra Troscianczyk, Marcelina Osinska, Dominik Lagowski, Urszula Kosior-Korzecka, Iwona Puzio
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Agriculture, Dairy & Animal Science
Ewa Tomaszewska, Piotr Dobrowolski, Malgorzata Swiatkiewicz, Janine Donaldson, Iwona Puzio, Siemowit Muszynski
Article
Environmental Sciences
Aneta Nowakiewicz, Przemyslaw Zieba, Sebastian Gnat, Marcelina Osinska, Dominik Lagowski, Urszula Kosior-Korzecka, Iwona Puzio, Jaroslaw Krol
Summary: This study aimed to investigate multidrug-resistant Enterococcus strains isolated from bats in Poland. The findings showed that a significant percentage of the isolates exhibited multi-drug resistance, with resistance to tetracycline, erythromycin, and rifampicin being the most common combination. Additionally, a high proportion of strains showed high-level aminoglycoside resistance. It was also observed that certain resistance genes were frequently detected together in the same strain, indicating potential common occurrence on mobile genetic elements.
ENVIRONMENTAL POLLUTION
(2021)
Article
Medicine, General & Internal
Iwona Puzio, Siemowit Muszynski, Piotr Dobrowolski, Malgorzata Kapica, Marta Pawlowska-Olszewska, Janine Donaldson, Ewa Tomaszewska
Summary: The study found that after gastrectomy, changes in small intestine morphology, enteric nervous system ganglia, hormones, and protein expression occurred, demonstrating intestinal enteroplasticity and neuroplasticity associated with changes in gastrointestinal tract condition.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Iwona Puzio, Dorota Grabos, Marek Bienko, Radoslaw P. Radzki, Aneta Nowakiewicz, Urszula Kosior-Korzecka
Summary: Supplementation of ovariectomized rats with Camelina sativa oil rich in PUFA can effectively improve bone health, increase bone density and strength, and inhibit adverse changes caused by estrogen deficiency.
Article
Food Science & Technology
Ewa Tomaszewska, Halyna Rudyk, Piotr Dobrowolski, Janine Donaldson, Izabela Swietlicka, Iwona Puzio, Daniel Kaminski, Dariusz Wiacek, Volodymyr Kushnir, Oksana Brezvyn, Viktor Muzyka, Renata Doraczynska, Siemowit Muszynski, Ihor Kotsyumbas
Summary: This experiment showed that pre-laying hens exposed to fumonisin B1 and fumonisin B2 experienced negative effects on their intestines and liver, including disruption of intestinal epithelial integrity, liver degeneration, and changes in bone tissue structure. Even at low doses, fumonisin administration can lead to intestinal barrier degradation and increased bone fracture risk in hens.
Article
Biochemistry & Molecular Biology
Ewa Tomaszewska, Halyna Rudyk, Izabela Swietlicka, Monika Hulas-Stasiak, Janine Donaldson, Marta Arczewska, Siemowit Muszynski, Piotr Dobrowolski, Iwona Puzio, Volodymyr Kushnir, Oksana Brezvyn, Viktor Muzyka, Ihor Kotsyumbas
Summary: The study revealed that exposure of pregnant dams to fumonisins can lead to negative effects on offspring bone metabolism and properties, with impacts depending on dose and sex. Effects were observed in body weight, bone length, and bone mechanical resistance, all linked to alterations in bone metabolism proteins.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Anna Skic, Iwona Puzio, Grzegorz Tymicki, Pawel Kolodziej, Marta Pawlowska-Olszewska, Kamil Skic, Karolina Beer-Lech, Marek Bienko, Krzysztof Golacki
Summary: Investigations on bone tissue response under different loading conditions are important. This study analyzed the influence of nesfatin-1 on the mechanical properties of rat humerus. Results showed that nesfatin-1 administration increased bone strength parameters. Ovariectomized rats had the most deformation and lowest fracture toughness. Impact tests were more sensitive than three-point bending tests. Maximum force values could be used to predict bone fracture toughness.
Article
Medicine, General & Internal
Ewa Tomaszewska, Siemowit Muszynski, Janine Donaldson, Piotr Dobrowolski, Deepesh K. P. Chand, Agnieszka Tomczyk-Warunek, Monika Hulas-Stasiak, Iwona Puzio, Krzysztof Lamorski, Cezary Slawinski, Miroslaw Jablonski, Tomasz Blicharski
Summary: The study investigated the effects of HMB supplementation during pregnancy on bone quality in spiny mice postpartum and post-lactation. Results suggest that HMB administration to pregnant females provides protection from bone loss, with a more positive impact on trabecular bone.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Grzegorz Tymicki, Iwona Puzio, Marta Pawlowska-Olszewska, Marek Bienko, Radoslaw Piotr Radzki
Summary: This study investigated the effects of nesfatin-1 administration on bone metabolism and properties in rats with established osteopenia. The results showed that treatment with nesfatin-1 limited bone loss, preserved bone architecture, and increased bone strength.
Article
Agriculture, Dairy & Animal Science
Ewa Tomaszewska, Halyna Rudyk, Dorota Wojtysiak, Janine Donaldson, Siemowit Muszynski, Marcin B. Arciszewski, Nataliia Lisova, Oksana Brezvyn, Iwona Puzio, Beata Abramowicz, Marta Pawlowska-Olszewska, Ihor Kotsyumbas, Piotr Dobrowolski
Summary: Cereal, a main component of animal feed, is often contaminated with mold and produces harmful metabolites, which can lead to disproportionate development in offspring and an increased risk of serious diseases like obesity and diabetes.
Article
Agriculture, Dairy & Animal Science
Malgorzata Kapica, Iwona Puzio, Beata Abramowicz, Barbara Badzian, Siemowit Muszynski, Ewa Tomaszewska
Summary: Adropin inhibits pancreatic exocrine secretion and this effect is related to the vagus nerve.
Article
Veterinary Sciences
S. Mozel, S. Szymanczyk, M. Krzysiak, I Puzio, A. Zacharko-Siembida, M. B. Arciszewski
POLISH JOURNAL OF VETERINARY SCIENCES
(2020)
Article
Agriculture, Dairy & Animal Science
Adrian Lopez-Catalina, Valentin Costes, Ramon Peiro-Pastor, Helene Kiefer, Oscar Gonzalez-Recio
Summary: Epigenetic marks can explain part of the phenotypic variance in animal breeding models. Nanopore sequencing shows high correlation with bisulphite sequencing in identifying DNA methylation marks. Different sequencing methods highlight differentially methylated genes and positions of economic interest in animal breeding.
