miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer

microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition

(2014) Aditya Parikh et al.   Nature Communications

Activin and TGFβ regulate expression of the microRNA-181 family to promote cell migration and invasion in breast cancer cells

(2013) Jean-Charles Neel et al.   CELLULAR SIGNALLING

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Polycyclic aromatic hydrocarbon (PAH)-mediated upregulation of hepatic microRNA-181 family promotes cancer cell migration by targeting MAPK phosphatase-5, regulating the activation of p38 MAPK

(2013) Mi-Kyung Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

(2012) Molly A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-181a promotes gastric cancer by negatively regulating tumor suppressor KLF6

(2012) Xiangyang Zhang et al.   TUMOR BIOLOGY

TGF-β in progression of liver disease

(2011) Steven Dooley et al.   CELL AND TISSUE RESEARCH

Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

(2011) Andrew S. Chu et al.   HEPATOLOGY

The Proapoptotic Bcl-2 Family Member Bim Plays a Central Role during the Development of Virus-Induced Hepatitis

(2011) C. Lauer et al.   JOURNAL OF IMMUNOLOGY

Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression

(2011) R. G. Rowe et al.   MOLECULAR AND CELLULAR BIOLOGY

An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

(2011) Philip A. Gregory et al.   MOLECULAR BIOLOGY OF THE CELL

miR-181a shows tumor suppressive effect against oral squamous cell carcinoma cells by downregulating K-ras

(2010) Ki-Hyuk Shin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis

(2010) Wen Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

Transforming growth factor-β and the hallmarks of cancer

(2010) Maozhen Tian et al.   CELLULAR SIGNALLING

Autocrine TGF-β protects breast cancer cells from apoptosis through reduction of BH3-only protein, Bim

(2010) Yukari Hoshino et al.   JOURNAL OF BIOCHEMISTRY

MiR-21 overexpression in human primary squamous cell lung carcinoma is associated with poor patient prognosis

(2010) Wen Gao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM

(2010) Y Wang et al.   ONCOGENE

Apoptosis and autophagy: BIM as a mediator of tumour cell death in response to oncogene-targeted therapeutics

(2009) Annette S. Gillings et al.   FEBS Journal

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

(2009) Junfang Ji et al.   HEPATOLOGY

Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice

(2009) Kojiro Taura et al.   HEPATOLOGY

TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

(2009) B Wang et al.   ONCOGENE

TGFβ-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2

(2008) Sneha Ramesh et al.   EMBO REPORTS

Hepatocyte-Specific Smad7 Expression Attenuates TGF-β–Mediated Fibrogenesis and Protects Against Liver Damage

(2008) Steven Dooley et al.   GASTROENTEROLOGY

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1

(2008) Tyler E. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY