Genes and hepatitis C: susceptibility, fibrosis progression and response to treatment

Fibrogenic Polymorphisms (TGF-β, PAI-1, AT) in Mexican Patients With Established Liver Fibrosis. Potential Correlation With Pirfenidone Treatment

(2016) Juan Armendáriz-Borunda et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Impact of IL28B Genotype on the Early and Sustained Virologic Response in Treatment-Naïve Patients With Chronic Hepatitis C

(2010) Albert Friedrich Stättermayer et al.   Clinical Gastroenterology and Hepatology

An IL28B Polymorphism Determines Treatment Response of Hepatitis C Virus Genotype 2 or 3 Patients Who Do Not Achieve a Rapid Virologic Response

(2010) Alessandra Mangia et al.   GASTROENTEROLOGY

Interleukin-28B Polymorphism Improves Viral Kinetics and Is the Strongest Pretreatment Predictor of Sustained Virologic Response in Genotype 1 Hepatitis C Virus

(2010) Alexander J. Thompson et al.   GASTROENTEROLOGY

Replicated Association Between an IL28B Gene Variant and a Sustained Response to Pegylated Interferon and Ribavirin

(2010) Jeanette J. McCarthy et al.   GASTROENTEROLOGY

Interleukin-28B genetic variants and hepatitis virus infection by different viral genotypes

(2010) Marco Antonio Montes-Cano et al.   HEPATOLOGY

644 GENOME-WIDE ASSOCIATION AND HIGH THROUGHPUT GENOTYPE IMPUTATION STUDIES CONFIRM A SUSCEPTIBILITY LOCUS TO HCV INFECTION ON 6P22.1–P21.31

(2010) J.A. Del Campo et al.   JOURNAL OF HEPATOLOGY

1180 A CHROMOSOME 19 SNP (RS12979860) PREDICTS OUTCOME (EVR/SVR) IN HCV PATIENTS TREATED WITH INTERFERON, INDEPENDENT OF PEGYLATION OR RIBAVIRIN

(2010) T. Asselah et al.   JOURNAL OF HEPATOLOGY

Association of interferon regulatory factor -7 gene polymorphism with liver cirrhosis in chronic hepatitis C patients

(2010) Radsamee Sermasathanasawadi et al.   LIVER INTERNATIONAL

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Apolipoprotein E interacts with hepatitis C virus nonstructural protein 5A and determines assembly of infectious particles

(2009) Wagane J. A. Benga et al.   HEPATOLOGY

A seven-gene signature (cirrhosis risk score) predicts liver fibrosis progression in patients with initially mild chronic hepatitis C

(2009) Moira Marcolongo et al.   HEPATOLOGY

Specific human leukocyte antigen class I and II alleles associated with hepatitis C virus viremia

(2009) Mark H. Kuniholm et al.   HEPATOLOGY

Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus

(2009) Susanne Knapp et al.   HEPATOLOGY

Association of IL-18 promoter polymorphism with liver disease severity in HCV-infected patients

(2009) K. Manohar et al.   Hepatology International

Low-density lipoprotein receptor variants are associated with spontaneous and treatment-induced recovery from hepatitis C virus infection

(2009) Andreas Mas Marques et al.   INFECTION GENETICS AND EVOLUTION

Interferon-λ Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

(2009) Hans Henrik Gad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection

(2009) Yonghong Li et al.   JOURNAL OF HEPATOLOGY

Genetic variation inCLDN1and susceptibility to hepatitis C virus infection

(2009) V. Bekker et al.   JOURNAL OF VIRAL HEPATITIS

Polymorphism of OAS-1 determines liver fibrosis progression in hepatitis C by reduced ability to inhibit viral replication

(2009) Chang-Zheng Li et al.   LIVER INTERNATIONAL

Protective KIR–HLA interactions for HCV infection in intravenous drug users

(2009) Joaquín Zúñiga et al.   MOLECULAR IMMUNOLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

Genome-wide and fine-resolution association analysis of malaria in West Africa

(2009) Muminatou Jallow et al.   NATURE GENETICS

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians

(2009) Yoichiro Kamatani et al.   NATURE GENETICS

Genomewide Association Study of Leprosy

(2009) Fu-Ren Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor

(2009) David M. Owen et al.   VIROLOGY

Polymorphisms of some cytokines and chronic hepatitis Band C virus infection

(2009) Qiu-Ju Gao et al.   WORLD JOURNAL OF GASTROENTEROLOGY

In Egyptians, a mutation in the lymphotoxin-α gene may increase susceptibility to hepatitis C virus but not that to schistosomal infection

(2008) M. Y. Elsammak et al.   ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY

A globally occurring indel polymorphism in the promoter of the IFNA2 gene is not associated with severity of malaria but with the positivity rate of HCV

(2008) Cristina Tena-Tomás et al.   BMC GENETICS

Association of functional polymorphism of ApoB promoter with hepatitis C virus infection

(2008) Chengliang Zhu et al.   CLINICA CHIMICA ACTA

Host Genetic Factors and Antiviral Immune Responses to Hepatitis C Virus

(2008) Chloe L. Thio   Clinics in Liver Disease

Regulatory Polymorphisms in the Interleukin‐18 Promoter Are Associated with Hepatitis C Virus Clearance

(2008) Ping An et al.   JOURNAL OF INFECTIOUS DISEASES

Multiple Sclerosis and Hepatitis C Virus Infection Are Associated with Single Nucleotide Polymorphisms in Interferon Pathway Genes

(2008) Giuliana Fortunato et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Association of interleukin-18 polymorphisms and plasma level with the outcome of chronic HCV infection

(2008) N. Bouzgarrou et al.   JOURNAL OF MEDICAL VIROLOGY

Translational control of the innate immune response through IRF-7

(2008) Rodney Colina et al.   NATURE

Effect of a thrombin receptor (protease-activated receptor 1,PAR-1) gene polymorphism in chronic hepatitis C liver fibrosis

(2007) Ana Martinelli et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY